Browsing by Author "Oz, Buge"

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Interobserver Agreement Among Histological Patterns and Diagnosis in Lung Adenocarcinomas
(DE GRUYTER OPEN LTD, 2014-01-01) Urer, Halide Nur; Ahiskali, Rengin; Arda, Naciye; Batur, Sebnem; Cinel, Leyla; Dekan, Gerhard; Fener, Neslihan; Firat, Pinar; Geleff, Silvana; Oz, Buge; Ozluk, Yasemin; Yildiz, Kursat; Yilmazbayhan, Emine Dilek; Zeren, Handan; Uysal, Atilla
Objective: The aim of this study was to investigate the interobserver agreement in determination of the dominant histological pattern and the final diagnosis in lung adenocarcinomas. Material and Method: A total of 12 patients with a diagnosis of primary lung adenocarcinoma were included in the study. Twelve pathologists from eight study centers were asked first to determine the dominant histological pattern in these cases and then to decide whether the final diagnosis was in situ, minimally invasive or invasive adenocarcinoma. Results: The kappa value for the agreement in determining the dominant pattern among the pathologists was 0.36 (p< 0.001), with the values for the lepidic, acinar, papillary, solid, micropapillary patterns and mucinous character of adenocarcinoma being 0.34, 0.28, 0.30, 0.80, 0.16 and 0.38 respectively (p< 0.001, p< 0.001, p< 0.001, p< 0.001, p< 0.001, p< 0.001). None of the cases was diagnosed as in situ adenocarcinoma. On the other hand, the kappa value for the agreement in differentiating minimally invasive from invasive adenocarcinoma among reviewers was 0.17 (p< 0.001). Conclusion: The agreement among pathologists in determining the subtype of lung adenocarcinomas that depends on the identification of the dominant pattern was at intermediate level. In addition, the agreement in deciding whether the case is minimally invasive or invasive, was at low level. The criteria defining the histological patterns should be clarified and described in more detail. Educational activities and larger multicenter studies might be helpful in improving the agreement and standardization.
The Approaches of Physicians Working in the Field of Pathology Regarding Forensic Pathology Practice and the Training Process
(DE GRUYTER OPEN LTD, 2013-01-01) Ersoy, Gokhan; Ozoran, Yavuz; Akcay, Arzu; Kolusayin, Melek Ozlem; Pakis, Isil; Urer, Halide Nur; Gulmen, Mete Korkut; Oz, Buge
Objective: Forensic autopsies are performed by the forensic medicine department and the microscopic examination processes by pathology specialists within the forensic medicine practice in Turkey. This disconnection in the process raises problems in the training of both branches. The aim of this study was to determine the awareness of pathology staff on forensic medicine practices and responsibilities and their opinion on the pathology training model in the forensic medicine specialty and to discuss the matter within the framework of the present situation and global applications. Material and Method: A 15-item questionnaire form distributed to the participant physicians during registration at the 21st National Pathology Congress held in 2011 was evaluated. Results: 94 participants responded. A negative opinion was expressed by 72\% about the interest in the general post-mortem process. The view that pathology specialists should undergo a separate training to perform autopsies was predominant and there was a general lack of interest in all kinds of autopsy processes. The percentage who said they knew the legal responsibility of a pathology specialist regarding forensic autopsies correctly was 37\%. The questions ``what are the necessary factors to contribute to the pathology training in forensic medicine{''} and ``if anything is required, which of them would take priority{''} were respectively answered as ``for me to be interested (46\%){''} and ``a system guaranteeing that training will always be given by pathology specialists (67\%){''}. Despite the possibility of becoming a forensic medicine specialist in two years, the mean answer score of the participants to the phrase `` I do not consider becoming a forensic medicine specialist{''} was 4.1 (out of 5). Conclusion: A reluctance among the pathologists in our country was seen regarding forensic medicine specialists being able to perform post-mortem microscopic examination. However, despite their legal responsibilities, their interest in forensic pathology practice was low. There seems to be rational factor that would increase this interest in the near future. Cooperation is necessary to enable forensic medicine specialists to perform post-mortem pathology procedures. This cooperation should be based on improving the training of pathology research assistants.
Towards Development of a Standard Terminology of the World Health Organization Classification of Tumors of the Central Nervous System in the Turkish Language, and a Perspective on the Practical Implications of the WHO Classification for Low and Middle Income Countries
(FEDERATION TURKISH PATHOLOGY SOC, 2022-01-01) Soylemezoglu, Figen; Oz, Buge; Egilmez, Reyhan; Pekmezci, Melike; Bozkurt, Suheyla; Danyeli, Ayca Ersen; Onguru, Onder; Kulac, Ibrahim; Tihan, Tarik
In our manuscript, we propose a common terminology in the Turkish language for the newly adopted WHO classification of the CNS tumors, also known as the WHO CNS 5th edition. We also comment on the applicability of this new scheme in low and middle income countries, and warn about further deepening disparities between the global north and the global south. This division, augmented by the recent COVID-19 pandemic, threatens our ability to coordinate efforts worldwide and may create significant disparities in the diagnosis and treatment of cancers between the ``haves{''} and the ``have nots{''}.