Celebi, IrfanBozkurt, GulpembePolat, Nedim2023-02-212023-02-212018-01-0110.1186/s12880-018-0261-9https://hdl.handle.net/11443/1907http://dx.doi.org/10.1186/s12880-018-0261-9Background: Malignant plasma cell proliferation may present as a disseminated disease (multiple myeloma), a solitary plasmacytoma of bone, or an extramedullary plasmacytoma of soft tissue. The latter plasmacytomas represent approximately 3\% of all plasma cell proliferations, and 80\% develop in the head-and-neck region. The unexpected clinical presentation of such masses may be present. Case presentation: Here, we report a rare case of primary tonsillar plasmacytoma in a 42-year-old female. The patient presented with asymmetric tonsillar hypertrophy that was resistant to antibiotherapy. Upon further workup, we found no evidence of multiple myeloma or light-chain disease. The patient underwent surgery and, at the last follow-up, exhibited no evidence of such disease. Conclusions: In adults presenting with asymptomatic tonsillar enlargement, the possibility of submucosal masses should be considered, thus encouraging the radiologist to evaluate crypts within the palatine tonsil on a postcontrast MRI, besides enlargement and signal change.PlasmacytomaMultiple myelomaMagnetic resonance imagingAsymmetric tonsillar enlargementArticleWOS:000435881000001