Tugan, Busra YilmazKarabas, LeventYenihayat, FatihSubasi, SevgiKesim, EnesOzkan, Berna2023-02-212023-02-212020-01-0110.4274/tjo.galenos.2020.21456https://hdl.handle.net/11443/2113http://dx.doi.org/10.4274/tjo.galenos.2020.21456Objectives: To assess changes in reflectivity of the retinal pigment epithelium (RPE), ellipsoid zone (EZ), and external limiting membrane (ELM) on spectral domain-optical coherence tomography (SD-OCT) images and the effects of reflectivity changes on visual acuity improvement after vitrectomy in macular hole patients. Materials and Methods: Twenty-four eyes of 24 patients with idiopathic full-thickness macular hole closed after vitrectomy were retrospectively reviewed. The ``plot profile{''} function of the medical imaging software was used by a single masked physician to analyze RPE, EZ, and ELM reflectivity on OCT images at postoperative 1 month and 12 months. Results: Absolute and relative EZ reflectivity showed highly significant increases at postoperative 12 months compared to 1 month (p<0.001 and p<0.001, respectively). Absolute and relative EZ reflectivity changes from postoperative month 1 to month 12 after macular hole surgery were significantly correlated with best corrected visual acuity improvement (p=0.012 and p=0.020, respectively). Conclusion: EZ reflectivity can be a predictor of functional and anatomical improvement after macular hole surgery.Absolute and relative reflectivityellipsoid zone reflectivitymacular holevitrectomyArticleWOS:000585785600007