Yapali, Suna2023-02-212023-02-212018-01-0110.4274/vhd.2018.0012https://hdl.handle.net/11443/951http://dx.doi.org/10.4274/vhd.2018.0012Recent advances have been made to develop and improve the serologic and molecular virologic tools for the diagnosis and optimal management of chronic hepatitis B (CHB) infection. Several biomarkers associated with the natural course of chronic hepatitis B infection virus (HBV) and the efficacy of antiviral treatment have been defined. This article reviews the impact of hepatitis B surface antigen, hepatitis B core-related antigen and HBV RNA on the natural history, treatment response and outcomes of CHB infection.Hepatitis B surface antigenhepatitis B core-related antigenhepatitis B virus RNAArticleWOS:000441968900006