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Item The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study(WILEY, 2022-01-01) Adamina, Michel; Ademuyiwa, Adesoji; Adisa, Adewale; Bhangu, Aneel A.; Bravo, Ana Minaya; Cunha, Miguel F.; Emile, Sameh; Ghosh, Dhruva; Glasbey, James C.; Harris, Benjamin; Keller, Debby; Lawday, Samuel; Lederhuber, Hans; Leventoglu, Sezai; Li, Elizabeth; Modolo, Maria Marta; Mittal, Rohin; Mohan, Helen M.; Nepogodiev, Dmitri; Parreno-Sacdalan, Marie Dione; Pata, Francesco; Pockney, Peter; Rutegard, Martin; Simoes, Joana F. F.; Smart, Neil; Varghese, Chris; Siaw-Acheampong, Kwabena; Benson, Ruth A.; Bywater, Edward; Chaudhry, Daoud; Dawson, Brett E.; Evans, Jonathan P.; Gujjuri, Rohan R.; Heritage, Emily; Jones, Conor S.; Kamarajah, Sivesh K.; Khatri, Chetan; Khaw, Rachel A.; Keatley, James M.; Knight, Andrew; Smart, Neil J.; Minaya-Bravo, Ana; Gallo, Gaetano; Moug, Susan; Di Saverio, Salomone; Vallance, Abigail; Vimalchandra, Dale; Griffiths, Ewen A.; Evans, Richard P. T.; Townen, Philip; Roberts, Keith; McKay, Siobhan; Isaac, John; Satoi, Sohei; Edwards, John; Coonar, Aman S.; Marchbank, Adrian; Caruana, Edward J.; Layton, Georgia R.; Patel, Akshay; Brunelli, Alessandro; Ford, Samuel; Desai, Anant; Gronchi, Alessandro; Fiore, Marco; Almond, Max; Tirotta, Fabio; Dumitra, Sinziana; Kolias, Angelos; Price, Stephen J.; Fountain, Daniel M.; Jenkinson, Michael D.; Hutchinson, Peter; Marcus, Hani J.; Piper, Rory J.; Lippa, Laura; Servadei, Franco; Esene, Ignatius; Freyschlag, Christian; Neville, Iuri; Rosseau, Gail; Schaller, Karl; Demetriades, Andreas K.; Robertson, Faith; Alamri, Alex; Shaw, Richard; Schache, Andrew G.; Winter, Stuart C.; Ho, Michael; Nankivell, Paul; Biel, Juan Rey; Batstone, Martin; Ganly, Ian; Vidya, Raghavan; Wilkins, Alex; Singh, Jagdeep K.; Thekinkattil, Dinesh; Sundar, Sudha; Fotopoulou, Christina; Leung, Elaine Yl; Khan, Tabassum; Chiva, Luis; Sehouli, Jalid; Fagotti, Anna; Cohen, Paul; Gutelkin, Murat; Ghebre, Rahel; Konney, Thomas; Pareja, Rene; Bristow, Rob; Dowdy, Sean; Shylasree, T. S.; Seenivasagam, Rajkumar Kottayasamy; Ng, Joe; Fujiwar, Keiichi; Stewart, Grant D.; Lamb, Benjamin; Narahari, Krishna; McNeill, Alan; Colquhoun, Alexandra; McGrath, John S.; Bromage, Steve; Barod, Ravi; Kasivisvanathan, Veeru; Klatte, Tobias; Abbott, Tom E. F.; Abukhalaf, Sadi; Ademuyiwa, Adesoji O.; Agarwal, Arnav; Akkulak, Murat; Alameer, Ehab; Alderson, Derek; Alakaloko, Felix; Albertsmeier, Markus; Alser, Osaid; Alshaar, Muhammad; Alshryda, Sattar; Arnaud, Alexis P.; Augestad, Knut Magne; Ayasra, Faris; Azevedo, Jose; Bankhead-Kendall, Brittany K.; Barlow, Emma; Beard, David; Blanco-Colino, Ruth; Brar, Amanpreet; Breen, Kerry A.; Bretherton, Chris; Buarque, Igor Lima; Burke, Joshua; Chaar, Mohammad; Chakrabortee, Sohini; Christensen, Peter; Cox, Daniel; Cukier, Moises; Davidson, Giana H.; Drake, Thomas M.; Edwards, John G.; Elhadi, Muhammed; Farik, Shebani; Fitzgerald, J. Edward; Garmanova, Tatiana; Gomes, Gustavo Mendonca Ataide; Grecinos, Gustavo; Gruendl, Magdalena; Halkias, Constantine; Harrison, Ewen M.; Hisham, Intisar; Hutchinson, Peter J.; Hwang, Shelley; Isik, Arda; Jonker, Pascal; Kaafarani, Haytham M. A.; Kruijff, Schelto; Lawani, Ismail; Litvin, Andrey; Loehrer, Andrew; Loffler, Markus W.; Lorena, Maria Aguilera; Major, Piotr; Martin, Janet; Mashbari, Hassan N.; Mazingi, Dennis; Metallidis, Symeon; Moore, Rachel; Moszkowicz, David; Ng-Kamstra, Joshua S.; Maimbo, Mayaba; Negoi, Ionut; Niquen, Milagros; Ntirenganya, Faustin; Olivos, Maricarmen; Oussama, Kacimi; Outani, Oumaima; Rivera, Carlos Jose Perez; Pinkney, Thomas D.; van der Plas, Willemijn; Qureshi, Ahmad; Radenkovic, Dejan; Ramos-De La Medina, Antonio; Richards, Toby; Roslani, April C.; Segura-Sampedro, Juan Jose; Santos, Irene; Sayyed, Raza; Schache, Andrew; Schnitzbauer, Andreas A.; Seyi-Olajide, Justina O.; Sharma, Neil; Shaw, Catherine A.; Shu, Sebastian; Soreide, Kjetil; Spinelli, Antonino; Sund, Malin; Tabiri, Stephen; Townend, Philip; Tsoulfas, Georgios; van Ramshorst, Gabrielle H.; Vimalachandran, Dale; Warren, Oliver J.; Wedderburn, Duane; Wrigh, Naomi; Valenzuela I, J.; Alurralde, C.; Caram, E. L.; Eskinazi, D. G.; Badra, R.; Garcia, J. S.; Lucchini, S. M.; Vasey, C.; Watson, E.; Cecire, J.; Salindera, S.; Sutherland, A.; Ahn, J. H.; Chen, S.; Gauri, N.; Jang, S.; Jia, F.; Mulligan, C. S.; Yang, W.; Ye, G.; Zhang, H.; Moss, J.; Richards, T.; Thian, A.; Vo, U. G.; Bagraith, K.; Chan, E.; Ho, D.; Jeyarajan, E.; Jordan, S.; Nolan, G. J.; Von Papen, M.; Wullschleger, M.; Dawson, A. C.; Drane, A.; Egoroff, N.; Gani, J.; Lott, N.; Pockney, P.; Phan, D.; Townend, D.; Bong, C.; Gundara, J.; Bowman, S.; Guerra, G. R.; Gerns, N.; Riddell, A.; Dudi-Venkata, N. N.; Kroon, H. M.; Sammour, T.; Mitchell, D.; Swinson, B.; Waldron, A.; Walker, P.; Lun, E. W. Y.; Messner, F.; Ofner, D.; Emmanuel, K.; Grechenig, M.; Gruber, R.; Harald, M.; Jager, T.; Ohlberger, L.; Presl, J.; Wimmer, A.; Samadov, E.; Barker, D.; Boyce, R.; Doyle, A.; Eastmond, A.; Gill, R.; O'Shea, M.; Padmore, G.; Paquette, N.; Phillips, E.; St John, S.; Walkes, K.; Flamey, N.; Pattyn, P.; Ceelen, W.; Van de Putte, D.; Van Nieuwenhove, Y.; Van Ramshorst, G.; Willaert, W.; Oosterlinck, W.; Van den Eynde, J.; Van den Eynde, R.; Aguiar Jr., Junior S.; Marques, T.; Camara, P.; De Lima, R. K.; Della Giustina, E.; Hoffmann V, P.; Nacif, L.; Ferro, Carvalho C.; Gomes, G. M. A.; Buarque I, Lima; Leite, Lira dos Santos A.; Pol-Fachin, L.; Bezerra, Santos T.; Silva, A.; Silvestre, D.; Barros, Vieira A.; Laporte, G.; Salem, M.; Awada, Barakat J.; Ijichi, T. R.; Kim, N. J.; Marreiro, A.; Muller, B.; Nunes, R.; Bodanese, B.; Isoton, J. C.; de Sampaio, Regina L.; Vendrame, C.; Sokolov, M.; Gribnev, P.; Boutros, M.; Caminsky, N.; Ghitulescu, G.; Groot, G.; Persad, A.; Pham, H.; Wood, M.; Demyttenaere, S.; Garfinkle, R.; Brown, C.; Karimuddin, A.; Lee, N.; Liu, J.; Kia, Madani T.; Phang, P. T.; Raval, M.; Tom, K.; Martel, A.; Nessim, C.; Stevenson, J.; Al Riyami, S.; Bali, K.; Bigam, D.; Dajani, K.; Dell, A.; Bellolio, F.; Besser, N.; Grasset, E.; Inzunza, M.; Martinic, Quintana M.; Altamirano, Riquoir C.; Esquide, Ruiz M.; Arias-Amezquita, F.; Cetares, C.; Murgueitio, Cortes N.; Gomez-Mayorga, J. L.; Abadia, M.; Bonilla, A.; Facundo, H.; Guevara, O.; Mora, Herrera D. R.; Ramirez, Jimenez L. J.; Manrique, E.; Morales, Pinilla R. E.; Ferro, Rey M.; Cuasquen, Velasquez B. G.; Karlovic, D.; Krsul, D.; Zelic, M.; Dijan, E.; Katusic, Z.; Mihanovic, J.; Rakvin, I.; Almezghwi, H.; Arslan, K.; Ozant, A.; Ozcay, N.; Frantzeskou, K.; Gouvas, N.; Kokkinos, G.; Papatheodorou, P.; Pozotou, I.; Stavrinidou, O.; Yiallourou, A.; Martinek, L.; Skrovina, M.; Szubota, I.; Peteja, M.; Zatecky, J.; Avlund, T.; Christensen, P.; Harbjerg, J. L.; Iversen, L. H.; Kjaer, D. W.; Kristensen, H. O.; Mekhael, M.; Ebbehoj, A. L.; Krarup, P.; Schlesinger, N.; Smith, H.; Crespo, A.; Diaz, P.; Rivas, R.; Tactuk, N.; El Kassas, M.; Omar, W.; Tawheed, A.; Talaat, M.; Abdelsamed, A.; Azzam, A. Y.; Salem, H.; Seleim, A.; Al Sayed, M.; Ashoush, F.; Elazzazy, E.; Essam, E.; Ewedah, M.; Hassan, E.; Metwalli, M.; Mourad, M.; Qatora, M. S.; Sabry, A.; Samih, A.; Abdelaal, Samir A.; Shehata, S.; Shenit, K.; Attia, D.; Kamal, N.; Osman, N.; Alaa, S.; Hamza, H. M.; Elghazaly, M. S.; Mohammed, M. M.; Nageh, M. A.; Saad, M. M.; Yousof, E. A.; Eldaly, A.; Alrahawy, M.; Sakr, A.; Soliman, H.; Soltan, H.; Amira, G.; Sallam, I.; Sherief, M.; Sherif, A.; Ghaly, G.; Hamdy, R.; Morsi, A.; Sherif, G.; Abdeldayem, H.; Salama I, Abdelkader; Balabel, M.; Fayed, Y.; Sherif, Ahmed Elshawadfy; Elmorsi, R.; Refky, B.; Bekele, K.; Kauppila, J. H.; Sarjanoja, E.; Helminen, O.; Huhta, H.; Beyrne, C.; Jouffret, L.; Marie-Macron, L.; Fredon, F.; Roux, A.; Lakkis, Z.; Manfredelli, S.; Chebaro, A.; El Amrani, M.; Lecolle, K.; Piessen, G.; Eveno, C.; Noiret, B.; Pruvot, Veziant J.; Zerbib, P.; Ballouhey, Q.; Barrat, B.; Taibi, A.; Bergeat, D.; Merdrignac, A.; Le Roy, B.; Perotto, L. O.; Scalabre, A.; Aime, A.; Ezanno, A. C.; Malgras, B.; Bouche, P. A.; Tzedakis, S.; Cotte, E.; Glehen, O.; Bendjemar, L.; Braham, H.; Charre, L.; El Arbi, N.; Police, A.; Volpin, E.; D'Urso, A.; Mutter, D.; Seeliger, B.; Bonnet, S.; Denet, C.; Fuks, D.; Laforest, A.; Pourcher, G.; Seguin-givelet, A.; Tribillon, E.; Duchalais, E.; Bork, U.; Fritzmann, J.; Praetorius, C.; Weitz, J.; Welsch, T.; Beyer, K.; Kamphues, C.; Lauscher, J.; Loch, F. N.; Schineis, C.; Albertsmeier, M.; Kappenberger, A.; Schiergens, T.; Werner, J.; Becker, R.; Jonescheit, J.; Pergolini, I.; Reim, D.; Herzberg, J.; Honarpisheh, H.; Strate, T.; Boeker, C.; Hakami, I.; Jw, Mall; Nowak, K.; Reinhard, T.; Kleeff, J.; Michalski, C.; Ronellenfitsch, U.; Bertolani, E.; Konigsrainer, A.; Loffler, M. W.; Quante, M.; Steidle, C.; Yurttas, C.; Izbicki, J.; Nitschke, C.; Perez, D.; Uzunoglu, F. G.; Antonakis, P.; Contis, I.; Dellaportas, D.; Gklavas, A.; Konstadoulakis, M.; Memos, N.; Papaconstantinou, I.; Polydorou, A.; Theodosopoulos, T.; Vezakis, A.; Antonopoulou I, M.; Manatakis, D. K.; Tasis, N.; Arkadopoulos, N.; Danias, N.; Economopoulou, P.; Frountzas, M.; Kokoropoulos, P.; Larentzakis, A.; Michalopoulos, N.; Parasyris, S.; Selmani, J.; Sidiropoulos, T.; Vassiliu, P.; Bouchagier, K.; Klimopoulos, S.; Paspaliari, D.; Stylianidis, G.; Akrivou, D.; Baxevanidou, K.; Bouliaris, K.; Chatzikomnitsa, P.; Delinasios, G.; Doudakmanis, C.; Efthimiou, M.; Giaglaras, A.; Kalfountzos, C.; Kolla, C.; Koukoulis, G.; Zervas, K.; Zourntou, S.; Baloyiannis, I.; Diamantis, A.; Perivoliotis, K.; Tzovaras, G.; Christidis, P.; Ioannidis, O.; Loutzidou, L.; Karaitianos, I. G.; Geroukalis, A.; Baili, E.; Charalabopoulos, A.; Liakakos, T.; Schizas, D.; Spartalis, E.; Syllaios, A.; Zografos, C.; Christou, C.; Papadopoulos, V.; Tooulias, A.; Tsoulfas, G.; Athanasakis, E.; Chrysos, E.; Tsiaoussis, I.; Xenaki, S.; Xynos, E.; Futaba, K.; Ho, M. F.; Hon, S.; Mak, T. W. C.; Ng, S.; Foo, C. C.; Banky, B.; Susztak, N.; Misra, S.; Pareek, P.; Vishnoi, J. R.; Jain, A.; Mishra, S.; Mishra, T.; Mitra, J. K.; Muduly, D.; Agrawal, A.; Garg, P. K.; Seenivasagam, Kottayasamy R.; Majumdar, K. S.; Mishra, N.; Singh, M. P.; Patnaik, Chyau S.; Rao, S.; Reddy, P.; Saksena, A. R.; Seshadri, Ayloor R.; Haque, P. D.; Jeyaraj, P.; Veetil, Kannummal S.; Mahajan, A.; Devarakonda, S.; Jesudason, M. R.; Mittal, R.; Moorthy, M.; Yezzaji, H.; Aggarwal, M.; Dhamija, P.; Kumar, A.; Chisthi, M.; George, G.; Kollengode, V. V.; Kuttanchettiyar, K. G.; Yadev, I.; Dharanipragada, K.; Kalayarasan, R.; Penumadu, P.; Mathew, S.; Akhtar, N.; Chaturvedi, A.; Gupta, S.; Kumar, V.; Rajan, S.; Agrawal, N.; Arora, A.; Chaturvedi, H.; Jain, M.; Kumar, S.; Singh, S.; Bhat, G. A.; Chowdri, N.; Mehraj, A.; Parray, F. Q.; Shah, Z. A.; Wani, R.; Ahmed, Z.; Bhat, M. A.; Laharwal, A.; Mahmood, M.; Mir, I.; Mohammad, Z.; Muzamil, J.; Rashid, A.; Singh, R.; Ahmed, A.; Jain, D.; Pipara, A.; Desoouza, A.; Pandey, D.; Pramesh, C. S.; Saklani, A.; Islam, A. A.; Kembuan, G.; Pajan, H.; Aremu, M.; Canas-Martinez, A.; Cullivan, O.; Murphy, C.; Owens, P.; Pickett, L.; Corrigan, M.; Daly, A.; Fleming, C. A.; Jordan, P.; Kayyal, M. Y.; Killeen, S.; Lynch, N.; O'Brien, S.; Syed, W. A. S.; Vernon, L.; Hanly, A.; Heneghan, H.; Kennelly, R.; Martin, S. T.; Winter, D.; Fahey, B. A.; Larkin, J.; Mccormick, P.; Mehigan, B. J.; Mohan, H.; Shokuhi, P.; Smith, J.; Bashir, Y.; Bass, G.; Connelly, T.; Creavin, B.; Earley, H.; Elliott, J. A.; Gillis, A. E.; Kavanagh, D.; Neary, P.; O'Riordan, J.; Reynolds, I. S.; Rice, D.; Ridgway, P. F.; Umair, M.; Whelan, M.; Corless, K.; Finnegan, L.; Fowler, A.; Hogan, A.; Lowery, A.; McKevitt, K.; Nugent, E.; Ryan, E. J.; Coffey, J. C.; Cunningham, R. M.; Devine, M.; Nally, D.; Peirce, C.; Hardy, N. P.; Neary, P. M.; O'Malley, S.; Ryan, M.; Gaziants, V.; Gold-Deutch, R.; Lavy, R.; Zmora, O.; Macina, S.; Mariani, N. M.; Opocher, E.; Ceretti, Pisani A.; Bianco, F.; Marino, M.; Marino V, M.; Mirabella, A.; Vaccarella, G.; Sena, G.; Agostini, C.; Alemanno, G.; Bartolini, I.; Bergamini, C.; Bruscino, A.; De Vincenti, R.; Di Bella, A.; Fortuna, L.; Maltinti, G.; Muiesan, P.; Prosperi, P.; Ringressi, M. N.; Risaliti, M.; Taddei, A.; Tucci, R.; Campagnaro, T.; Guglielmi, A.; Pedrazzani, C.; Rattizzato, S.; Ruzzenente, A.; Turri, G.; Altomare, D. F.; Papagni, V.; Picciariello, A.; Bellora, P.; D'Aloisio, G.; Ferrari, M.; Francone, E.; Gentilli, S.; Nikaj, H.; Bianchini, M.; Chiarugi, M.; Coccolini, F.; Cremonini, C.; Di Franco, G.; Furbetta, N.; Gianardi, D.; Guadagni, S.; Morelli, L.; Musetti, S.; Palmeri, M.; Tartaglia, D.; Anania, G.; Carcoforo, P.; Chiozza, M.; De Troia, A.; Radica, Koleva M.; Portinari, M.; Sibilla, M. G.; Urbani, A.; Fabbri, N.; Feo V, C.; Gennari, S.; Parini, S.; Righini, E.; Annessi, V.; Ruiz, Castro C.; Giunta, A.; Montella, M. T.; Zizzo, M.; Grossi, U.; Novello, S.; Romano, M.; Rossi, S.; Zanus, G.; Esposito, G.; Frongia, F.; Pisanu, A.; Podda, M.; Belluco, C.; Lauretta, A.; Montori, G.; Moras, L.; Olivieri, M.; Feo, C. F.; Perra, T.; Porcu, A.; Scanu, A. M.; Aversano, A.; Carbone, F.; Delrio, P.; Di Lauro, K.; Bucci, Fares A.; Rega, D.; Spiezio, G.; Pirozzolo, G.; Recordare, A.; Vignotto, C.; Calabro, M.; Farnesi, F.; Lunghi, E. G.; Muratore, A.; Federico, Pipitone N. S.; De Palma, G.; Luglio, G.; Pagano, G.; Tropeano, F. P.; Baldari, L.; Boni, L.; Cassinotti, E.; Cosimelli, M.; Fiore, M.; Guaglio, M.; Sorrentino, L.; Agnes, A.; Alfieri, S.; Belia, F.; Biondi, A.; Cozza, V.; D'Ugo, D.; De Simone, V.; Litta, F.; Lorenzon, L.; Marra, A. A.; Marzi, F.; Parello, A.; Persiani, R.; Ratto, C.; Rosa, F.; Scrima, O.; Sganga, G.; Belli, A.; Izzo, F.; Patrone, R.; Foppa, C.; Carvello, M. M.; De Lucia, F.; Spinelli, A.; Aprile, A.; Batistotti, P.; Massobrio, A.; Pertile, D.; Scabini, S.; Soriero, D.; Garberini, De Manzoni A.; Mazzotti, F.; Pasini, F.; Ugolini, G.; Barone, R.; Birolo, S. L.; Caccetta, M.; Deirino, A.; Garino, M.; Grasso, M.; Marafante, C.; Masciandaro, A.; Moggia, E.; Mungo, S.; Murgese, A.; Raggio, E.; Federico, P.; Maida, P.; Marra, E.; Marte, G.; Petrillo, A.; Tammaro, P.; Tufo, A.; Berselli, M.; Borroni, G.; Cocozza, E.; Conti, L.; Desio, M.; Rizzi, A.; Baldi, C.; Corbellini, C.; Sampietro, G. M.; Bordoni, P.; Clarizia, G.; Fleres, F.; Franzini, M.; Grechi, A.; Longhini, A.; Spolini, A.; Baldini, E.; Capelli, P.; Isolani, S. M.; Ribolla, M.; Bondurri, A.; Colombo, F.; Ferrario, L.; Guerci, C.; Maffioli, A.; Armao, T.; Ballabio, M.; Bisagni, P.; Longhi, M.; Madonini, M.; Impellizzeri, H.; Inama, M.; Moretto, G.; Mochet, S.; Usai, A.; Incollingo, P.; Giacometti, M.; Zonta, S.; Cosentino, Marino L.; Sagnotta, A.; Lc, Nespoli; Tamini, N.; Anastasi, A.; Bartalucci, B.; Bellacci, A.; Canonico, G.; Capezzuoli, L.; Di Martino, C.; Ipponi, P.; Linari, C.; Montelatici, M.; Nelli, T.; Spagni, G.; Tirloni, L.; Vitali, A.; Abate, E.; Casati, M.; Laface, L.; Schiavo, M.; Arminio, A.; Cotoia, A.; Lizzi, V.; Vovola, F.; Vergari, R.; D'Ugo, S.; Depalma, N.; Spampinato, M. G.; Annicchiarico, A.; Catena, F.; Giuffrida, M.; Perrone, G.; Baronio, G.; Carissimi, F.; Montuori, M.; Pinotti, E.; Brachini, G.; Chiappini, A.; Cicerchia, P. M.; Cirillo, B.; De Toma, G.; Fiori, E.; Fonsi, G. B.; Iannone, I.; La Torre, F.; Lapolla, P.; Meneghini, S.; Mingoli, A.; Sapienza, P.; Zambon, M.; Capolupo, G. T.; Carannante, F.; Mazzotta, E.; Gattolin, A.; Migliore, M.; Rimonda, R.; Sasia, D.; Travaglio, E.; Chessa, A.; Fiorini, A.; Norcini, C.; Colletti, G.; Confalonieri, M.; Costanzi, A.; Frattaruolo, C.; Mari, G.; Monteleone, M.; Locatelli, A.; Riva, C.; Balconi, A.; De Nardi, P.; Parise, P.; Vignali, A.; Belvedere, A.; Bernante, P.; Droghetti, M.; Jovine, E.; Neri, J.; Parlanti, D.; Pezzuto, A. P.; Poggioli, G.; Rottoli, M.; Russo, I. S.; Tanzanu, M.; Violante, T.; Borghi, F.; Cianflocca, D.; Grimaldi, Di Maria S.; Donati, D.; Gelarda, E.; Giraudo, G.; Giuffrida, M. C.; Marano, A.; Palagi, S.; Pellegrino, L.; Peluso, C.; Testa, V.; Agresta, F.; Prando, D.; Zese, M.; Armatura, G.; Frena, A.; Bertelli, G.; Marinello, P.; Notte, F.; Scotton, G.; Cervellera, M.; Gori, A.; Sartarelli, L.; Tonini, V.; Gallo, G.; Sammarco, G.; Vescio, G.; Di Marzo, F.; Kanemitsu, Y.; Moritani, K.; Al Abdallah, M.; Ayasra, F.; Ayasra, Y.; Qasem, A.; Fahmawee, T.; Hmedat, A.; Obeidat, K.; Abou Chaar, M. K.; Al-Masri, M.; Al-Najjar, H.; Alawneh, F.; Aldokali, N.; Senossi, O.; Subhi, M. T.; Algallai, M.; Alwarfly, S.; AlZAEDE, S.; Gahwagi, M.; Moftah, M.; Burgan, D.; Kamoka, E.; Kilani I, A.; Abdelkabir, M.; Altomi, I.; Abdulwahed, E.; Alshareea, E.; Aribi, N.; Aribi, S.; Biala, M.; Ghamgh, R.; Alsoufi, A.; Ellojli, I.; Kredan, A.; Msherghi, A.; Alshareef, K.; Alkadiki, Ghadah Z.; Almaadany, Faraj S.; Bradulskis, S.; Dainius, E.; Kubiliute, E.; Parseliunas, A.; Subocius, A.; Venskutonis, D.; Rasoaherinomenjanahary, F.; Razafindrahita, J. B.; Samison, L. H.; Ngo, C. W.; Ramasamy, S.; Hamdan, K. H.; Razali I, Md; Tan, J. A.; Thanapal, M. R.; Choong, E.; Lim, R. Z. M.; Sahid, Nik Amin; Hayati, F.; Jayasilan, J.; Rk, Sriram; Subramaniam, S.; Ibrahim, A. F.; Jusoh, Che A.; Hussain, A. H.; Sidek, Mohamed A. S.; Yunus, Mohd M. F.; Soh, J. Y.; Wong, M. P.; Zakaria, A. D.; Zakaria, Z.; Azman, Mohd Z. A.; Fathi, N. Q.; Roslani, A. C.; Xavier, R.; Alvarez, M. R.; Cordera, F.; Hernandez, R.; Martinez, Soule C. E.; Hasan, Aboharp Z.; Otoniel, L. R.; Duran, Sosa E. E.; Melchor-Ruan, J.; Banuelos, Romero E.; Vilar-Compte, D.; Buerba, G. A.; Mercado, M. A.; Posadas-Trujillo, O. E.; Salgado-Nesme, N.; Sarre, C.; Amrani, L.; Benkabbou, A.; El Ahmadi, B.; El Bouazizi, Y.; Belkhadir, Z. H.; Ghannam, A.; Majbar, A. M.; Mohsine, R.; Souadka, A.; Hompes, R.; Meima-van Praag, E. M.; Pronk, A. J. M.; Sharabiany, S.; Grotenhuis, B. A.; Hartveld, L.; Ebben, L.; Kuiper, S.; Melenhorst, J.; Poeze, M.; Posma-Bouman, L.; Derksen, T.; Franken, J.; Oosterling, S.; Konsten, J.; Van Heinsbergen, M.; Adeyeye, A.; Enoch, E.; Nwabuoku, S. E.; Sholadoye, T. T.; Tolani, M. A.; Olaogun, J.; Abiyere, H.; Babalola, O.; Okunlola, A.; Sani, Ali S.; Chinda, J.; Garba, S.; Mshelbwala, P.; Olori, S.; Olute, A.; Osagie, O.; Ogolekwu I, Pius; Umar, A.; Lo, Abdur-Rahman; Jo, Bello; Olasehinde, O.; Popoola, A. 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K.; Yanishev, A.; Litvin, A.; Litvina, Y.; Provozina, A.; Agapov, M.; Garmanova, T.; Kazachenko, E.; Markaryan, D.; Galliamov, E.; Kakotkin, V.; Kubyshkin, V.; Semina, E.; Kamalov, A.; Novikova, A.; Zakharenko, A.; Alshahrani, M.; Alsharif, F.; Eskander, M.; Majrashi, S.; Mashat, A.; Alharthi, M.; Aljiffry, M.; Basendowah, M.; Malibary, N.; Nassif, M.; Samkari, A.; Trabulsi, N.; Azab, A. M.; Alqahtani, D.; Jaloun, H.; Mudawi, I.; Al Awwad, S.; Alghamdi, M.; Alnumani, T.; Awad, S.; Sharara, I. 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A.; Kara, H.; Karahasanoglu, T.; Uras, C.; Akbas, A.; Altinel, Y.; Calikoglu, F.; Ercan, G.; Ercetin, C.; Meric, S.; Tokocin, M.; Vartanoglu, T.; Yigitbas, H.; Dogangun, M.; Iflazoglu, N.; Cennet, O.; Ha, Dincer; Erol, T.; Alhamed, A.; Ergun, S.; Sanli, A. N.; Uludag, S. S.; Velidedeoglu, M.; Zengin, A. K.; Kara, Y.; Bozkurt, M. A.; Kocatas, A.; Eyuboglu, K.; Guner, A.; Usta, M. A.; Balik, E.; Bugra, D.; Kulle, C. B.; Guler, S. A.; Tatar, O. C.; Utkan, N. Z.; Yildirim, A.; Yuksel, E.; Abbasov, A.; Yanar, H.; Akin, E.; Altintoprak, F.; Cakmak, G.; Demir, H.; Dikicier, E.; Firat, N.; Gonullu, E.; Kamburoglu, M. B.; Kucuk, I. F.; Mantoglu, B.; Kucuk, G. O.; Uyanik, M. S.; Goksoy, B.; Bozkurt, E.; Capkinoglu, E.; Guven, O.; Mihmanli, M.; Omeroglu, S.; Tanal, M.; Yetkin, G.; Akalin, M.; Arican, C.; Avci, E. 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L.; Smith, C.; Vimalachandran, D.; Emslie, K.; Pl, Labib; Minto, G.; Natale, J.; Panahi, P.; Rogers, L. J.; Abubakar, A.; Rahman, Akhter M. M.; O'Brien, H.; Sasapu, K.; Ng, H. J.; Day, A.; Hunt, A.; Laskar, N.; Gupta, A.; Steinke, J.; Thrumurthy, S.; Massie, E.; McGivern, K.; Rutherford, D.; Wilson, M.; Bacarese-Hamilton, T.; Ip, M.; James, A.; Salerno, G.; Stockdale, T.; Handa, S.; Kaushal, M.; Kler, A.; Patel, P.; Redfern, J.; Tezas, S.; Aawsaj, Y.; Barry, C.; Blackwell, L.; Emerson, H.; Fisher, A.; Katory, M.; Mustafa, A.; Kretzmer, L.; Lalou, L.; Manku, B.; Parwaiz, I.; Stafford, J.; Abdelkarim, M.; Asqalan, A.; Gala, T.; Ibrahim, S.; Maw, A.; Mithany, R.; Morgan, R.; Venkatesan, Sundaram G.; Banfield, D.; Boal, M.; Brown, O.; Dean, H.; Boulton, A. J.; Hardie, C. M.; McNaught, C.; Karandikar, S.; Naumann, D.; Chen, F.; Cheung, J.; Ayorinde, J.; Chase, T.; Cuming, T.; Ghanbari, A.; Humphreys, L.; Tayeh, S.; Ibrahim, Aboelkassem A.; Evans, C.; Ikram, H.; Loubani, M.; Nazir, S.; Robinson, A.; Sehgal, T.; Wilkins, A.; Dixon, J.; Jha, M.; Thulasiraman V, S.; Viswanath, Y.; Curl-Roper, T.; Delimpalta, C.; Liao, C. C. L.; Velchuru, V.; Westwood, E.; Bond-Smith, G.; Mastoridis, S.; Tebala, G. D.; Verberne, C.; Anscomb, N.; Baldwin-Smith, R.; Davies, M.; Grainger, C.; Haji, A.; Haq, A.; Nunoo-Mensah, J. W.; Rizk, M.; Bhatti I, M.; Boyd-Carson, H.; Elsey, E.; Gemmill, E.; Herrod, P.; MohammedJibreel, M.; Lenzi, E.; Saafan, T.; Sapre, D.; Sian, T.; Watson, N.; Athanasiou, A.; Burke, J.; Costigan, F.; Elkadi, H.; Johnstone, J.; Nahm, C.; Annamalai, S.; Ashmore, C.; Kourdouli, A.; Chean, C. S.; Dharamavaram, S.; Kulkarni, N.; Pereira, I.; Shanthakunalan, K.; Srikumar, B.; Askari, A.; Cirocchi, N.; Kudchadkar, S.; Patel, K.; Sagar, J.; Talwar, R.; Abdalla, M.; Ismail, O.; Newton, K.; Stylianides, N.; Aderombi, A.; Bajomo, O.; Beatson, K.; Garrett V, W.; Ng, V.; Al-Habsi, R.; Divya, G. S.; Dixon, F.; Keeler, B. D.; Egan, R. J.; Fabre, I.; Harries, R.; Li, Z.; Parkins, K.; Spencer, N.; Thompson, D.; Gemmell, C.; Grieco, C.; Hunt, L.; Ali, Mahmoud F.; Seebah, K.; Shaikh, I.; Sreedharan, L.; Youssef, M.; Shah, J.; Baguley, M.; Heer, B.; Rogers, M.; Woods, R.; Mills, S. J.; Sahnan, K.; Ahmed, M. E.; Si, Bukhari; Illingworth, B.; Kanthasamy, S.; Knights, E.; Sl, Ong; Pujari, R.; Tan, K. H. M.; Vanker, R.; Michel, M.; Patil, S.; Ravindran, S.; Sarveswaran, J.; Scott, L.; Khan, J.; Bhangu, A.; Ld, Cato; Kamal, M.; Kulkarni, R.; Parente, A.; Saeed, S.; Vijayan, D.; English, C.; Evans, J.; Fell, A.; Halkias, C.; Merh, R.; Nikolaou, S.; Kaul, S.; Khan, A. H.; Khan, F.; Mukherjee, S.; Patel, M.; Sarigul, M.; Adiamah, A.; Brewer, H.; Chowdhury, A.; Humes, D.; Jackman, J.; Koh, A.; Lewis-Lloyd, C.; Oyende, O.; Reilly, J.; Worku, D.; Bisset, C.; Moug, S.; Chadha, R.; Math, S.; Sarantitis, I.; Timbrell, S.; Vitone, L.; Faulkner, G.; Brixton, G.; Findlay, L.; Majkowska, A.; Manson, J.; Potter, R.; Bhalla, A.; Chia, Z.; Daliya, P.; Grimley, E.; Malcolm, F. L.; Theophilidou, E.; Daniels, I. R.; Fowler, G. E.; Massey, L. H.; McDermott, F. D.; Rajaretnam, N.; Angamuthu, N.; Chowdhury, S.; Gilliland, J.; Hart, C.; Knowles, J.; Mirnezami, R.; Varcada, M.; Beamish, A. J.; Magowan, D.; Nassa, H.; Price, C.; Smith, L.; Solari, F.; Tang, A. M.; Williams, G.; Davies, E.; Hawkin, P.; Raymond, T.; Ryska, O.; Baron, R.; Gahunia, S.; McNicol, F.; Russ, J.; Szatmary, P.; Thomas, A.; Jayasinghe, J. D.; Knowles, C.; Ledesma, F. S.; Minicozzi, A.; Navaratne, L.; Ramamoorthy, R.; Sohrabi, C.; Thaha, M. A.; Venn, M.; Atherton, R.; Brocklehurst, M.; McAleer, J.; Parkin, E.; Aladeojebi, A.; Ali, M.; Gaunt, A.; Hammer, C.; Stebbing, J.; Coomber, E.; Williams, O.; Bunni, J.; Fairhurst, K.; Mitchell, S.; Richards, S.; Hraishawi, I.; McIlmunn, C.; McIntosh, S.; Bhasin, S.; Bodla, A. S.; Burahee, A.; Crichton, A.; Fossett, R.; Yassin, N.; Barlow, C.; Ding, D.; Foster, J.; Longstaff, L.; Brown, S. R.; Lee, M.; Newman, T.; Steele, C.; Baker, A.; Konstantinou, C.; Ramcharan, S.; Wilkin, R. J. W.; Colvin V, H.; Shakoor, Z.; Lawday, S.; Lyons, A.; Newman, S.; Chung, E.; Hagger, R.; Hainsworth, A.; Karim, A.; Owen, H.; Ramwell, A.; Williams, K.; Hall, J.; Harris, G.; Royle, T.; Lj, Watson; Asaad, P.; Brown, B.; Duff, S.; Khan, A.; Moura, F.; Wadham, B.; Mccluney, S.; Parmar, C.; Shah, S.; Babar, M. S.; Goodrum, S.; Whitmore, H.; Balasubramaniam, D.; Jayasankar, B.; Kapoor, S.; Ramachandran, A.; Beech, N.; Chand, M.; Green, L.; Kiconco, H.; McEwen, R.; Pereca, J.; Arumugam, S.; Ibrahim, B.; Khan, K.; Gash, K.; Gourbault, L.; Maccabe, T. A.; Newton, C.; Baig, M.; Bates, H.; Dunne, N.; Khajuria, A.; Dr, Sarma; Shortland, T.; Tewari, N.; Akhtar, M. A.; Brunt, A.; McIntyre, J.; Milne, K.; Rashid, M. M.; Sgro, A.; Stewart, K. E.; Turnbull, A.; Gossedge, G.; O'Donnell, S.; Oldfield, F.; Gonzalez, Aguilar M.; Talukder, S.; Eskander, P.; Hanna, M.; Olivier, J.; Basnyat, P.; Davis, H.; Montauban, P.; Shrestha, A.; Magee, C.; Powell, S.; Flindall, I.; Hanson, A.; Mahendran, V.; Green, S.; Lim, M.; MacDonald, L.; Miu, V.; Onos, L.; Sheridan, K.; Young, R.; Alam, F.; Griffiths, O.; Houlden, C.; Kolli, V. S.; Lala, A. K.; Seymour, Z.; Consorti, E.; Gonzalez, R.; Kwan-Feinberg, R.; Liu, T.; Cooper, Z.; Hirji, S.; Mahvi, D.; Okafor, B.; Roxo, V.; Salim, A.; Loehrer, A.; Telma, K.; Bokenkamp, M.; Haynes, A. B.; Hill, C.; Leede, E.; McElhinney, K.; Olson, K. A.; Riley, C.; Bigelow, B.; Etchill, E. W.; Gabre-Kidan, A.; Jenny, H. E.; Kent, A.; Ladd, M. R.; Long, C.; Malapati, H.; Margalit, A.; Rapaport, S.; Rose, J.; Stevens, K.; Tsai, L.; Vervoort, D.; Yesantharao, P.; Klaristenfeld, D.; Huynh, K. T.; Kaafarani, H.; Naar, L.; Qadan, M.; Cha, D. E.; Gleeson, E.; Horn, C.; Sarpel, U.; Bhama, A.; Colling, K.; Najarian, M.; Azam, M.; Choudhry, A.; Marx, W.; Chokshi, R.; Glass, N.; Tsui, G.; Abel, M. K.; Boeck, M.; Chern, H.; Kornblith, L. Z.; Nunez-Garcia, B.; Ozgediz, D.; Sarin, A.; Varma, M. G.; Abbott, D.; Acher, A.; Aiken, T.; Barrett, J.; Foley, E.; Schwartz, P. B.; Zafar, S. N.; Hawkins, A. T.; Maiga, A.; Ruzgar, N. M.; Sion, M.; Ullrich, S.; Al-Naggar, H.; Al-Shehari, M.; Almassaudi, A.; Alsayadi, M.; Alsayadi, R.; Shream, S.; Uberruck, L.; Angelo, M.; Alga, A.; Celebi, F.; Colak, E.; Ogucu, H.; Arulanantham, A.; Bandara, G. B. K. D.; Jayarajah, U.; Ravindrakumar, S.; Rodrigo, V. S. D.; Collaborative, COVIDSurg; EuroSurg; European Soc Coloproctology, E. S. C. P.; Surg, Global Initiative Children's; GlobalSurg; GlobalPaedSurg; ItSURG; PTSurg; SpainSurg; SICCR, Italian Soc Colorectal Surg; ASiT, Assoc Surg Training; Irish Surg Res Collaborative, I. S. R. C.; Retrope, Transatlantic Australasian; Italian Soc Surg Oncology, S. I. C. O.Aim The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. Methods This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. Results Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6\% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5\% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7\% vs. 91.9\%, P = 0.032) and lower rates of emergency surgery (4.5\% vs. 22.5\%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95\% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95\% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. Conclusion One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease.Item Current treatment strategies in malignant pleural mesothelioma with a treatment algorithm(VIA MEDICA, 2019-01-01) Sayan, Mutlay; Eren, Mehmet Fuat; Gupta, Apar; Ohri, Nisha; Kotek, Ayse; Babalioglu, Ibrahim; Kaplan, Sedenay Oskeroglu; Duran, Ozge; Or, Ozlem Derinalp; Cukurcayie, Funda; Kurtul, Neslihan; Bicakci, Beyhan Ceylaner; Kutuk, Tugce; Senyurek, Sukran; Turk, Ali; Jabbour, Salma K.; Atalar, BanuMalignant pleural mesothelioma (MPM) is a rare disease with a poor prognosis. The main therapeutic options for MPM include surgery, chemotherapy, and radiation therapy (RT). Although multimodality therapy has been reported to improve survival, not every medically operable patient is able to undergo all recommended therapy. With improvements in surgical techniques and systemic therapies, as well as advancements in RT, there has been a potential new paradigm in the management of this disease. In this review, we discuss the current literature on MPM management and propose a functional treatment algorithm.Item Adult Spinal Deformity Over 70 Years of Age: A 2-Year Follow-Up Study(INT SOC ADVANCEMENT SPINE SURGERY-ISASS, 2019-01-01) Karabulut, Cem; Ayhan, Selim; Yuksel, Selcen; Nabiyev, Vugar; Vila-Casademunt, Alba; Pellise, Ferran; Alanay, Ahmet; Sanchez Perez-Grueso, Francisco Javier; Kleinstuck, Frank; Obeid, Ibrahim; Acaroglu, Emre; Grp, European Spine StudyBackground: Treatment of adult spinal deformity (ASD) in elderly patients remains controversial. The aim of this study was to identify the factors leading to the surgical treatment by comparing the baseline characteristics of operative versus nonoperative patients, to evaluate the safety and efficacy of surgery, and to compare operative and nonoperative management of elderly ASD patients at the end of the 2-year follow-up period. Methods: Retrospective review of a multicenter, prospective ASD database was performed. Patients over 70 years of age with ASD who were scheduled to undergo surgical treatment and who were treated and/or followed without surgical intervention participated in the study. Demographic, clinical, surgical, and radiological characteristics and health-related quality-of-life (HRQOL) (Core Outcome Measures Index {[}COMI], Oswestry Disability Index {[}ODI], Short-Form-36 Mental Component Summary {[}SF-36 MCS], Short-Form-36 Physical Component Summary {[}SF36-PCS], and Scoliosis Research Society-22 {[}SRS-22]) parameters of such group of patients were evaluated pre-and posttreatment. Results: A total 90 patients (females: 71, males: 29Item The Influence of Diagnosis, Age, and Gender on Surgical Outcomes in Patients With Adult Spinal Deformity(SAGE PUBLICATIONS LTD, 2018-01-01) Ayhan, Selim; Yuksel, Selcen; Nabiyev, Vugar; Adhikari, Prashant; Villa-Casademunt, Alba; Pellise, Ferran; Sanchez Perez-Grueso, Francisco; Alanay, Ahmet; Obeid, Ibrahim; Kleinstueck, Frank; Acaroglu, Emre; Grp, European Spine StudyStudy Design: Retrospective review of prospectively collected data from a multicentric database. Objectives: To determine the clinical impact of diagnosis, age, and gender on treatment outcomes in surgically treated adult spinal deformity (ASD) patients. Methods: A total of 199 surgical patients with a minimum follow-up of 1 year were included and analyzed for baseline characteristics. Patients were separated into 2 groups based on improvement in health-related quality of life (HRQOL) parameters by minimum clinically important difference. Statistics were used to analyze the effect of diagnosis, age, and gender on outcome measurements followed by a multivariate binary logistic regression model for these results with statistical significance. Results: Age was found to affect SF-36 PCS (Short From-36 Physical Component Summary) score significantly, with an odds ratio of 1.017 (unit by unit) of improving SF-36 PCS score on multivariate analysis (P < .05). The breaking point in age for this effect was 37.5 years (AUC = 58.0, P = .05). A diagnosis of idiopathic deformity would increase the probability of improvement in Oswestry Disability Index (ODI) by a factor of 0.219 and in SF-36 PCS by 0.581 times (P < .05). Gender was found not to have a significant effect on any of the HRQOL scores. Conclusions: Age, along with a diagnosis of degenerative deformity, may have positive effects on the likelihood of improvement in SF-36 PCS (for age) and ODI (for diagnosis) in surgically treated patients with ASD and the breaking point of this effect may be earlier than generally anticipated. Gender does not seem to affect results. These may be important in patient counseling for the anticipated outcomes of surgery.Item Purely extradural spinal nerve root hemangioblastomas(MEDKNOW PUBLICATIONS \& MEDIA PVT LTD, 2016-01-01) Aytar, Murat Hamit; Yener, Ulas; Eksi, Murat Sakir; Kaya, Behram; Ozgen, Serdar; Sav, Aydin; Alanay, AhmetSpinal nerve root hemangioblastomas present mostly as intradural-extradurally. Purely extradural spinal nerve root hemangioblastoma is a very rare entity. In this study, we aimed to analyze epidemiological perspectives of purely extradural spinal nerve root hemangioblastomas presented in English medical literature in addition to our own exemplary case. PubMed/MEDLINE was searched using the terms ``hemangioblastoma,{''} ``extradural,{''} ``spinal,{''} and ``nerve root.{''} Demographical variables of age, gender, concomitant presence of von Hippel-Lindau (VHL) diseaseItem Comparison of effects of energy based devices on quality of life after sutureless thyroidectomy(LIPPINCOTT WILLIAMS \& WILKINS, 2022-01-01) Arikan, Akif Enes; Ozyegin, Mustafa AtesObjective: In current literature, no studies evaluated effect of energy-based vessel-sealing-devices on quality of life after sutureless total thyroidectomies. This study aimed to identify any potential differences between two energy-based vessel-sealing-devices (Harmonic Focus, Ligasure LF1212) in patients with benign thyroid disorders who underwent sutureless total thyroidectomy. Materials and methods: Differences in quality of life of patients were evaluated using data obtained by Thy-PRO-39-Tr questionnaire prior to and four-week after surgery. Total and domain-based alterations in quality of life were compared between groups according to energy-based vessel-sealing-devices type (Group L, Group H). Additionally, data including demographics, height, weight, body mass index, neck circumference, sternomental distance were collected. Results: Of 1032 patients, 200 were eligible for study, at the end 193 were analysed. There were no differences between groups in terms of age, sex, body mass index, tobacco use. Analysis did not reveal any differences in overall quality of life between groups (P = .42). However, in ``eye symptoms{''} (P < .001) and ``cognitive functions{''} (P = .002) domains, Harmonic provided statistically improved quality of life. Effect on cognitive function was greater in patients of advanced age. Conclusions: Especially in elderly patients with worsening eye conditions and cognitive functions, use of Harmonic may enhance patients' outcome by increasing quality of life in addition to optimizing surgical outcome when compared to Ligasure.Item Are surgical and non-operating room intervention safe in the COVID-19 pandemic? A retrospective study(CAMBRIDGE UNIV PRESS, 2021-01-01) Yildirim, Serap Aktas; Sarikaya, Zeynep Tugce; Ulugol, Halim; Ozata, Sanem; Aksu, Ugur; Toraman, Fevzi; Grp, C. O. V. I. D.-19 StudyLittle is known about the impact of COVID-19 on the outcomes of patients undergoing surgery and intervention. This study was conducted between 20 March and 20 May 2020 in six hospitals in Istanbul, and aimed to investigate the effects of surgery and intervention on COVID-19 disease progression, intensive care (ICU) need, mortality and virus transmission to patients and healthcare workers. Patients were examined in three groups: group I underwent emergency surgery, group II had an emergency non-operating room intervention, and group III received inpatient COVID-19 treatment but did not have surgery or undergo intervention. Mortality rates, mechanical ventilation needs and rates of admission to the ICU were compared between the three groups. During this period, patient and healthcare worker transmissions were recorded. In total, 1273 surgical, 476 non-operating room intervention patients and 1884 COVID-19 inpatients were examined. The rate of ICU requirement among patients who had surgery was nearly twice that for inpatients and intervention patients, but there was no difference in mortality between the groups. The overall mortality rates were 2.3\% in surgical patients, 3.3\% in intervention patients and 3\% in inpatients. COVID-19 polymerase chain reaction positivity among hospital workers was 2.4\%. Only 3.3\% of infected frontline healthcare workers were anaesthesiologists. No deaths occurred among infected healthcare workers. We conclude that emergency surgery and non-operating room interventions during the pandemic period do not increase postoperative mortality and can be performed with low transmission rates.Item Predictive parameters of early postoperative complications in Crohn's disease: Single team experience(AVES, 2018-01-01) Atasoy, Deniz; Aghayeva, Afag; Bilgin, Ismail Ahmet; Erzin, Yusuf; Bayraktar, Ilknur Erenler; Baca, Bilgi; Karahasanoglu, Tayfun; Hamzaoglu, IsmailBackground/Aims: Most of the patients with Crohn's disease (CD) may require at least one surgical procedure over their lifetime. However, these patients tend to have a high incidence of postoperative complications. The aim of this retrospective study was to investigate the predictive parameters of postoperative complications in CD. Materials and Methods: All consecutive patients with CD between March 2001 and March 2016 who underwent bowel resection were included to this study. Postoperative complications were divided asItem Cytoreductive Surgery Followed by Hyperthermic Intraperitoneal Chemotherapy: Morbidity and Mortality Analysis of Our Patients(ORTADOGU AD PRES \& PUBL CO, 2012-01-01) Karadayi, Kursat; Turan, Mustafa; Karadayi, Sule; Alagozlu, Hakan; Kilickap, Saadettin; Buyukcelik, Abdullah; Sarkis, Cihat; Yucel, Birsen; Boztosun, Abdullah; Cetin, Meral; Yilmaz, Abdulkerim; Yanik, Ali; Sen, MetinObjective: The purpose of this study was to analyze the morbidity and mortality of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and early postoperative intraperitoneal chemotherapy (EPIC) with closed abdomen technique in the treatment of peritoneal surface malignancies. Material and Methods: Twenty-six patients (8 with ovarian cancer, 7 peritoneal mesothelioma, 6 colorectal cancer, 3 uterine sarcoma, 1 peritoneal carcinoma and 1 with gastric cancer) underwent 27 procedures. Peritonectomy was performed with complete removal of all the involved visceral and parietal peritoneum. HIPEC was performed with the closed abdominal technique using preheated (42.5 degrees C) perfusate for 60 minutes. EPIC was continued for postoperative 5 days. Results: All patients underwent resection of the lesions. Total pentonectomy was performed in 12 patients, while subtotal or partial peritonectomy was carried out in 14 according to the spread of carcinomatosis. Completeness of cytoreduction score of our patients was 0 in 18 patients, 1 in 6 patients and 2 in 2 patients. Major morbidity developed in 7 patients (27\%). CRS+HIPEC+EPIC yielded acceptable morbidity and mortality rates. Of the 26 patients, 20 (77\%) were alive without evidence of disease with a mean follow-up period of 13 6 months. Overall 1 year survival was 60\%. Conclusion: Cytoreductive approach combined with intraperitoneal chemotherapy prolongs survival in selected patients with peritoneal carcinomatosis (PC) with acceptable morbidity and mortality.Item Epilepsy Surgery in Pediatric Patients: A Single-Center Experience(KARE PUBL, 2019-01-01) Tanrikulu, Bahattin; Isik, Ugur; Ozek, Memet MetinObjectives: Epilepsy surgery is one of the treatment options in pediatric patients with drug-resistant epilepsy. Our aim is to share demographic data, surgical outcome, possible surgical complications, and factors that affect surgical outcome in pediatric patients with drug-resistant epilepsy who were operated in our clinic. Methods: In this retrospective study, 85 patients who were operated in Acibadem Hospital Pediatric Epilepsy Surgery Clinic between years 2005 and 2017 were included. We investigated the influence of sex, age at seizure onset, side and frequency of seizures, time to surgery, type of epilepsy surgery, and histopathology on pediatric epilepsy surgery outcome. Surgical outcome was assessed by Engel classification system. Statistical analysis was performed with SPSS 20.0 software. Results: There were 56 male (66\%) and 29 female (34\%) participants. Median of the age of seizure onset is 2 years (1 day-15 years). Median of age at operation is 6.2 years (3 months-16 years). Median of the duration of seizure until surgery is 3.2 years (3 months-15.5 years). Median follow-up is 5.6 years (3 months-13.5 years). There were permanent motor neurological deficits in 3 patients (3.5\%). The best surgical outcome was achieved in patients with resective surgeries (p<0.01). Age at seizure onset was the most important factor that influences surgical outcome in our patients (p<0.05). Conclusion: Epilepsy surgery is one of the safe and effective treatment options in pediatric patients with drug-resistant epilepsy.