Human papillomavirus prevalence and type in liquid-based cervical samples from Turkish women in a selected risk group
dc.contributor.author | Akyar, Ism | |
dc.contributor.author | Aydin, Ozlem | |
dc.contributor.author | Yakicier, Mustafa Cengiz | |
dc.contributor.author | Kocagoz, Zuhtu Taml | |
dc.contributor.author | Ince, Umit | |
dc.contributor.author | Unsal, Ibrahim | |
dc.date.accessioned | 2023-02-21T12:32:16Z | |
dc.date.available | 2023-02-21T12:32:16Z | |
dc.date.issued | 2013-01-01 | |
dc.description.abstract | Aim: To detect the prevalence and type distribution of human papillomavirus (HPV) in different cytological diagnostic categories. Materials and methods: Between 2007 and 2010, a total of 1014 liquid-based thin preparations of cervical smears were selected and classified according to cytology results. HPV DNA polymerase chain reaction (PCR) was also performed using these samples. HPV DNA-positive samples were genotyped by DNA sequencing. Results: Of those enrolled in the study, 45.3\% were negative cytologically, 36.4\% had atypical squamous cells of undetermined significance, 0.3\% had atypical squamous cells preventing the exclusion of a high-grade squamous intraepithelial lesion, 16.8\% showed a low-grade squamous intraepithelial lesion, and 1.3\% had an high-grade squamous intraepithelial lesion. Conclusion: PCR assays showed HPV positivity in 63.0\% of cytologically negative and 90.8\% of cytologically positive samples. The most common types of HPV detected were 16, 6, 18, 31, 66, 56, 53, 81, 45, and 62. Of HPV DNA-positive samples, 47.7\% were high, 4.7\% were intermediate, and 17.9\% were low risk. The high-risk types of HPV detected were 16, 18, 31, 56, 53, 45, 62, 58, 59, 67, 51, 35, 73, 52, 33, 39, 68, and 82. | |
dc.description.issue | 6 | |
dc.description.pages | 963-970 | |
dc.description.volume | 43 | |
dc.identifier.doi | 10.3906/sag-1211-67 | |
dc.identifier.uri | https://hdl.handle.net/11443/942 | |
dc.identifier.uri | http://dx.doi.org/10.3906/sag-1211-67 | |
dc.identifier.wos | WOS:000325156700015 | |
dc.publisher | TUBITAK SCIENTIFIC \& TECHNICAL RESEARCH COUNCIL TURKEY | |
dc.relation.ispartof | TURKISH JOURNAL OF MEDICAL SCIENCES | |
dc.subject | Cytology | |
dc.subject | human papillomavirus DNA | |
dc.subject | genotype | |
dc.subject | polymerase chain reaction | |
dc.title | Human papillomavirus prevalence and type in liquid-based cervical samples from Turkish women in a selected risk group | |
dc.type | Article |
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