Electron Microscopic Comparison of Radial Artery Grafts in Non-Diabetic and Diabetic Coronary Bypass Patients
Electron Microscopic Comparison of Radial Artery Grafts in Non-Diabetic and Diabetic Coronary Bypass Patients
Tarih
2016-01-01
Yazarlar
Gursoy, Mete
Guzel, Elif
Erturkuner, Pelin
Cakir, Idil
Duygu, Egemen
Gulcan, Fusun
Hokenek, A. Faruk
Süreli Yayın başlığı
Süreli Yayın ISSN
Cilt Başlığı
Yayınevi
WILEY
Dergi Adı
JOURNAL OF CARDIAC SURGERY
Özet
Objective: We compared electron microscopic histologic changes of the radial artery grafts in non-diabetic and diabetic patients. Methods: Thirty-six patients were divided into three groups according to their diabetic status (Group I had no diabetes mellitus {[}DM], Group II had type two DM and HbA1c levels were <7.5\%, and Group III had type 2 DM but HbA1c levels were >7.5\%). Distal parts of radial artery grafts were evaluated with scanning electron microscopy in a blind fashion by two histologists. Electron microscopic scores were compared among the groups. Results: Radial artery electron microscopic scores were significantly different between group 1, 2 and 1, 3 and 2, 3 (p = 0.028, p<0.001, and p<0.001). In linear regression analysis, duration of DM (p = 0.027) and fasting plasma glucose (p = 0.001) were found as independent risk factors for histologic changes of radial artery grafts. Conclusion: Duration of DM and poor glycemic control were found to be associated with radial artery electron microscopic changes.