Lack of Sunlight Exposure Influence on Primary Glioblastoma Survival
dc.contributor.author | Mutlu, Hasan | |
dc.contributor.author | Akca, Zeki | |
dc.contributor.author | Erden, Abdulsamet | |
dc.contributor.author | Aslan, Tuncay | |
dc.contributor.author | Ucar, Kadir | |
dc.contributor.author | Kaplan, Bunyamin | |
dc.contributor.author | Buyukcelik, Abdullah | |
dc.date.accessioned | 2023-02-21T12:38:23Z | |
dc.date.available | 2023-02-21T12:38:23Z | |
dc.date.issued | 2014-01-01 | |
dc.description.abstract | Background: The prognosis of primary glioblastoma (GBM) is poor. Approximately 2/3 of primary brain tumor diagnoses are GBM, of which 95\% are primary lesions. In this study, we aimed to evaluate whether more sunlight exposure has an effect on survival of patients with primary GBM. Materials and Methods: A total of 111 patients with primary GBM were enrolled from Kayseri in inner Anatolia which has a cold climate (n: 40) and Mersin in Mediterranean region with a warm climate and more sunlight exposure (n: 71). The patients with primary GBM were divided into two groups as Kayseri and Mersin and compared for progression free survival (PFS) and overall survival (OS). Results: The PFS values were 7.0 and 4.7 months for Kayseri and Mersin groups, respectively (p=0.10) and the repsective OS values were 13.3 and 9.4 months (p=0.13). We did not found any significant difference regarding age, sex, comorbidity, smoking, surgery, resurgery, adjuvant chemoradiotherapy and palliative chemotherapy between the groups. Conclusions: We found that more sunlight exposure had no impact on prognosis of patients with primary GBM, adding inconsistency to the literature about the relationship between sunlight and GBM. | |
dc.description.issue | 10 | |
dc.description.pages | 4165-4168 | |
dc.description.volume | 15 | |
dc.identifier.doi | 10.7314/APJCP.2014.15.10.4165 | |
dc.identifier.uri | https://hdl.handle.net/11443/2377 | |
dc.identifier.uri | http://dx.doi.org/10.7314/APJCP.2014.15.10.4165 | |
dc.identifier.wos | WOS:000338634400009 | |
dc.publisher | ASIAN PACIFIC ORGANIZATION CANCER PREVENTION | |
dc.relation.ispartof | ASIAN PACIFIC JOURNAL OF CANCER PREVENTION | |
dc.subject | Glioblastoma | |
dc.subject | sunlight | |
dc.subject | vitamin D | |
dc.subject | survival | |
dc.subject | brain tumor | |
dc.title | Lack of Sunlight Exposure Influence on Primary Glioblastoma Survival | |
dc.type | Article |