Lack of Sunlight Exposure Influence on Primary Glioblastoma Survival

dc.contributor.authorMutlu, Hasan
dc.contributor.authorAkca, Zeki
dc.contributor.authorErden, Abdulsamet
dc.contributor.authorAslan, Tuncay
dc.contributor.authorUcar, Kadir
dc.contributor.authorKaplan, Bunyamin
dc.contributor.authorBuyukcelik, Abdullah
dc.date.accessioned2023-02-21T12:38:23Z
dc.date.available2023-02-21T12:38:23Z
dc.date.issued2014-01-01
dc.description.abstractBackground: The prognosis of primary glioblastoma (GBM) is poor. Approximately 2/3 of primary brain tumor diagnoses are GBM, of which 95\% are primary lesions. In this study, we aimed to evaluate whether more sunlight exposure has an effect on survival of patients with primary GBM. Materials and Methods: A total of 111 patients with primary GBM were enrolled from Kayseri in inner Anatolia which has a cold climate (n: 40) and Mersin in Mediterranean region with a warm climate and more sunlight exposure (n: 71). The patients with primary GBM were divided into two groups as Kayseri and Mersin and compared for progression free survival (PFS) and overall survival (OS). Results: The PFS values were 7.0 and 4.7 months for Kayseri and Mersin groups, respectively (p=0.10) and the repsective OS values were 13.3 and 9.4 months (p=0.13). We did not found any significant difference regarding age, sex, comorbidity, smoking, surgery, resurgery, adjuvant chemoradiotherapy and palliative chemotherapy between the groups. Conclusions: We found that more sunlight exposure had no impact on prognosis of patients with primary GBM, adding inconsistency to the literature about the relationship between sunlight and GBM.
dc.description.issue10
dc.description.pages4165-4168
dc.description.volume15
dc.identifier.doi10.7314/APJCP.2014.15.10.4165
dc.identifier.urihttps://hdl.handle.net/11443/2377
dc.identifier.urihttp://dx.doi.org/10.7314/APJCP.2014.15.10.4165
dc.identifier.wosWOS:000338634400009
dc.publisherASIAN PACIFIC ORGANIZATION CANCER PREVENTION
dc.relation.ispartofASIAN PACIFIC JOURNAL OF CANCER PREVENTION
dc.subjectGlioblastoma
dc.subjectsunlight
dc.subjectvitamin D
dc.subjectsurvival
dc.subjectbrain tumor
dc.titleLack of Sunlight Exposure Influence on Primary Glioblastoma Survival
dc.typeArticle

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