The Role of New Viral Biomarkers in Chronic Hepatitis B: Ready to Use in the Clinical Practice?
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Date
Authors
Journal Title
Journal ISSN
Volume Title
dc.identifier.issn
dc.identifier.doi
10.4274/vhd.2018.0012
dc.identifier.other
dc.description.volume
24
dc.description.issue
2
AUG
AUG
Publisher
GALENOS YAYINCILIK
DOI
10.4274/vhd.2018.0012
Abstract
Recent advances have been made to develop and improve the serologic and molecular virologic tools for the diagnosis and optimal management of chronic hepatitis B (CHB) infection. Several biomarkers associated with the natural course of chronic hepatitis B infection virus (HBV) and the efficacy of antiviral treatment have been defined. This article reviews the impact of hepatitis B surface antigen, hepatitis B core-related antigen and HBV RNA on the natural history, treatment response and outcomes of CHB infection.