Browsing by Author "Celebi, Ali Riza Cenk"

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Assessment of risk factors on eye dryness in young adults using visual display device in both contact lens wearers and non-wearers
(SPRINGER, 2022-01-01) Altinbas, Ekin; Elibol, Alperen; Firatli, Goktug; Ayhan, Cemre; Celebi, Ali Riza Cenk
Purpose Researchers are interested in examining the impact of visual display devices (VDDs) on the development of dry eye illness because their use is becoming more common among college students. The goal of this study was to see if there was a link between certain risk factors and the development of eye dryness in VDDs using young adults who wore contact lenses and those who did not. Methods The self-administrated survey was hosted in Google Forms, sent via e-mail to the participants. It consisted of two parts of assessing different risk factors (i.e., environmental conditions, angle of gaze, and years of VDD use) with contact lens use and Ocular Surface Disease Index (OSDI) questionnaire. The OSDI scores of the entire sample who suffer from dry eye and the subgroup using contact lenses were calculated. The relationship between different risk factors with the OSDI scores was also assessed. Results A total of 274 young adults from college students and academic staff (216 female, 58 male) were suffering from eye dryness. Eighty-eight of the 274 participants wore contact lenses. The mean OSDI scores of the 274 young adults were 32.92. Mean OSDI scores in contact lens wearers and non-wearers were 34.36 and 32.24, respectively (p < 0.01). There was a statistically significant relationship between OSDI score and indoor environmental conditions in computer using VDD group. Using a computer in a dark environment and above the line of sight resulted in a higher OSDI scores. Females who wore contact lenses while using a computer for more than three years had significantly higher OSDI scores than non-wearer females. Tablet type VDD use increased the mean ODSI scores of the contact lens wearers significantly. Conclusions Dry eye symptoms were shown to be increased in the contact lens wearer group with the increased duration of computer VDD use, decreased indoor environmental brightness conditions, and above the line of sight.
Comparison of success between external and endonasal dacryocystorhinostomy in primary acquired nasolacrimal duct obstruction in Turkish cohort
(KARE PUBL, 2020-01-01) Karasu, Bugra; Kiray, Gulunay; Eris, Erdem; Perente, Irfan; Celebi, Ali Riza Cenk
OBJECTIVE: To evaluate the results and recurrence rates of external and endonasal dacryocystorhinostomy (DCR) surgery in patients with primary acquired nasolacrimal duct obstruction (PANDO) in Turkish Cohort. METHODS: Medical records were reviewed in all patients who underwent surgery for PANDO between January 2010 and September 2014 in a tertiary university hospital retrospectively. The patients were followed up on the first day, first month, third month and sixth month postoperatively. Lacrimal drainage system and recurrence rates were recorded. RESULTS: This study was conducted in 81 patients, 27 of whom were men (33.3\%) and 54 were women (66.7\%). The mean follow-up time was 30.1316.42 months (range 6-62 months). The mean age was 50.51 +/- 12.47 years (range 16 to 77 years). External DCR was used in 44 (66.7\%) of the cases and endonasal DCR was used in 37 (45.7\%) of the cases. Surgical results of DCR were divided into three groups based on the integrity and openness of the lacrimal drainage pathway in all PANDO patients. Operation success rates of these data revealed that 45 (55.6\%) cases were recorded as successful, 20 (24.7\%) of the cases were accepted as partially successful and 16 (19.8\%) of the cases were deemed as unsuccessful. Based on these data, surgical success rates were found in 38 (86.4\%) patients in external DCR and 27 (73\%) patients in endonasal DCR. Surgical failure rates were six (13.6\%) in external DCR and 10 (27\%) in endonasal DCR. There was no statistically significant difference between success rates and recurrences in both groups (p>0.05). CONCLUSION: Endoscopic DCR produced simple, minimally invasive and preferable results compared to external DCR in the Turkish population. Although the success of external DCR is higher and the recurrence is lower than endoscopic DCR, with the outcomes of this study, endoscopic DCR can be tried as the first choice to protect the patient from major surgery and anesthesia in PANDO.
Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease
(HINDAWI LTD, 2016-01-01) Celebi, Ali Riza Cenk; Mirza, G. Ertugrul
Purpose. To compare central corneal thickness (CCT) values via Spectral Domain-Optical Coherence Tomography (SD-OCT) and ultrasonic pachymetry in patients with severe dry eye disease (DED) to determine the level of agreement between these 2 methods. Methods. The paired samples t-test was used to compare CCT values in severe DED patients. Matching analysis between methods was performed using intraclass correlation coefficient (ICC). Intrasession reliability of the measurement methods was calculated via the concordance correlation coefficient (CCC), variation equivalent, and Pearson's correlation coefficient. The Bland-Altman procedure was used to graphically represent the differences between CCT values. Results. The study included 56 eyes of 24 female and 4 male patients. Mean age of the patients was 50.9 +/- 11.3 years. Mean CCT via Cirrus SD-OCT was 523.82 +/- 30.98 mu m versus 530.050 +/- 31.85 mu m via ultrasonic pachymetry (paired samples t-test, P < 0.001). The Bland-Altman plot showed good agreement between the examiners. The ICC for repeatability was 0.974. The CCC between the 2 methods' CCT values was 0.973. The variation equivalent was 0.976 and Pearson's correlation coefficient was 99.3\%, which also indicated high correlation between the 2 methods' measurements. Conclusions. The present findings show that in patients with severe DED Cirrus SD-OCT provides reliable intraobserver CCT values.
Evaluation of the `Hedgehog' signaling pathways in squamous and basal cell carcinomas of the eyelids and conjunctiva
(SPANDIDOS PUBL LTD, 2016-01-01) Celebi, Ali Riza Cenk; Kiratli, Hayyam; Soylemezoglu, Figen
The purpose of the present study was to assess the role of hedgehog signaling pathway in the carcinogenesis of eyelid skin and conjunctival epithelial malignant tumors. The study was conducted on specimens from 41 patients with cutaneous eyelid basal cell carcinoma, 22 with bulbar conjunctival squamous cell carcinoma, 12 with bulbar conjunctival intraepithelial neoplasia. Major molecules of Hedgehog signaling pathway (Sonic Hedgehog {[}Shh] and Patched-1 {[}Ptch-1] and Glioma-associated oncogene {[}Gli-1]) were evaluated in paraffin-embedded tissue specimens using immunohistochemical staining. For each specimen, the percentage (<10\%, 10-50\%, > 50\%) and the intensity of the immunohistochemical staining (graded from 0 to 3) were calculated and the scores obtained by multiplication of two values were analyzed using the Kruskall-Wallis test. Shh and Ptch-1 expression levels were statistically significantly lower in the basal cell carcinoma group compared with the squamous cell carcinoma group (P= 0.043 for Shh
Hyperbaric Oxygen Therapy for Central Retinal Artery Occlusion: Patient Selection and Perspectives
(DOVE MEDICAL PRESS LTD, 2021-01-01) Celebi, Ali Riza Cenk
The central retinal artery occlusion (CRAO) is a rare ophthalmological emergency that can occur in the eye. CRAO can affect persons of any age, however it is most common in people over the age of 60. CRAO is associated with a number of risk factors, including giant cell arteritis, carotid artery atherosclerosis, cardiogenic emboli, hypertension, smoking, diabetes, and thromboembolic disease. The chance of each of these etiologies being present is assessed during the course of the investigation. Hyperbaric oxygen treatment (HBOT) is classified by the American Heart Association for CRAO at level IIb. In accordance with that, HBOT might be considered for the treatment of such a severe condition. HBOT can maintain retinal oxygenation during ischemic events by allowing oxygen to diffuse through choroidal capillaries that have been exposed to elevated partial pressures of oxygen. As a result, ischemia-related damage is reversed if applied within proper time frame. The amount of time that has passed prior to initiation of HBOT is considered to be the most critical factor in determining the best visual prognosis. According to the Undersea and Hyperbaric Medical Society, patients who are identified with CRAO after the onset of symptoms should be evaluated for HBOT within 24 hours. HBOT has the advantage of having a low risk profile, and it can be utilized to improve visual outcomes in proper patients.
Hyperbaric Oxygen Therapy in Branch Retinal Artery Occlusion in a 15-Year-Old Boy with Methylenetetrahydrofolate Reductase Mutation
(HINDAWI LTD, 2015-01-01) Celebi, Ali Riza Cenk; Kadayifcilar, Sibel; Eldem, Bora
Purpose. To report the efficacy of hyperbaric oxygen (HBO) therapy in a case of branch retinal artery occlusion (BRAO) in a 15-year-old boy. Methods. We report a 15-year-old boy with sudden loss of vision due to BRAO. Examination included laboratory evaluation for systemic risk factors. Follow-up exams included visual acuity, fundus examination, fundus fluorescein angiography, and visual field testing. HBO therapy was employed for treatment. Results. Medical history was positive for isolated glucocorticoid deficiency. Laboratory evaluation disclosed hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) mutation. The visual acuity 0.05 at presentation improved to 0.8 after 20 days of HBO therapy. There was no change on visual fields. Conclusion. In this pediatric case, HBO therapy was useful in the treatment of BRAO.
Incidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care units
(BMJ PUBLISHING GROUP, 2018-01-01) Bas, Ahmet Yagmur; Demirel, Nihal; Koc, Esin; Isik, Dilek Ulubas; Hirfanoglu, Ibrahim Murat; Tunc, Turan; Sari, Fatma Nur; Karatekin, Guner; Koklu, Esad; Altunhan, Huseyin; Turgut, Hatice; Narter, Fatma; Tarakci, Nuriye; Tekgunduz, Kadir Serafettin; Ozkiraz, Servet; Aydemir, Cumhur; Ozdemir, Ahmet; Cetinkaya, Bilin; Kazanci, Ebru; Tastekin, Ayhan; Calkavur, Sebnem; Ozyurt, Banu Mutlu; Demirelli, Yasar; Asker, Huseyin Selim; Mutlu, Birgul; Uygur, Ozgun; Ozkan, Hilal; Armangil, Didem; Ozlu, Ferda; Mert, Mustafa Kurthan; Ergin, Hacer; Ozcan, Beyza; Bas, Evrim Kiray; Okulu, Emel; Acunas, Betul; Celik, Ulker; Uslu, Sait Ilker; Mutlu, Mehmet; Demir, Nihat; Eroglu, Funda; Gokmen, Zeynel; Beken, Serdar; Bayraktar, Bilge Tanyeri; Hakan, Nilay; Kucuktasci, Kazim; Orman, Aysen; Comert, Serdar; Ertugrul, Sabahattin; Ustun, Nuran; Sahin, Ozlem; Terek, Demet; Kale, Yusuf; Konak, Murat; Yurttutan, Sadik; Aydemir, Ozge; Zenciroglu, Aysegul; Sarici, Dilek; Guzoglu, Nilufer; Hamilcikan, Sahin; Gursoy, Tugba; Tuzun, Funda; Ors, Rahmi; Arslan, Selda; Akdag, Arzu; Memisoglu, Asli; Yasa, Beril; Hekimoglu, Berna; Turan, Ozden; Aylanc, Hakan; Takci, Sahin; Celik, Tolga; Sahin, Suzan; Kilic, Ilknur; Kara, Caner; Tunay, Zuhal Ozen; Celik, Gokhan; Gozen, Ibrahim; Satirtav, Gunhal; Polat, Nihat; Oral, Ayse Yesim; Tokgoz, Mine; Keles, Sadullah; Bilgin, Burak; Ugurbas, Silay Canturk; Karaca, Cagatay; Keskek, Nedime Sahinoglu; Ekinci, Dilbade Yildiz; Balci, Ozlem; Altan, Emir Volkan; Bakbak, Sevda; Ceylan, Nihan Aksu; Kimyon, Sabit; Alyamac, Gunay; Ture, Gamze; Yildiz, Meral; Calis, Feyza; Sizmaz, Selcuk; Sukgen, Emine; Cetin, Ebru Nevin; Ozcimen, Muammer; Demir, Semra Tiryaki; Atila, Huban; Ozal, Altan; Tufaner, Gokhan; Yucel, Ozlem Eski; Kola, Mehmet; Seven, Erbil; Ozdek, Sengul; Durukan, Ali Hakan; Kal, Ali; Celebi, Ali Riza Cenk; Koytak, Ibrahim Arif; Alacamli, Goksu; Esme, Arif; Catak, Onur; Perente, Irfan; Sahin, Alparslan; Akcakaya, Aylin Ardagil; Kiray, Gulunay; Nalcaci, Serhat; Aksoy, Umit; Bakbak, Berker; Comez, Aysegul; Gursoy, Huseyin; Kabatas, Emrah Utku; Petricli, Ikbal Seza; Yumusak, Mehmet Erhan; Kirgiz, Ahmet; Uludag, Gunay; Yaman, Aylin; Dadaci, Zeynep; Karatas, Ali; Celiker, Hande; Cebeci, Zafer; Esenulku, Mahmut Cenap; Akkoyun, Imren; Ersan, Ismail; Demir, Selim; Kadayifcilar, Sibel; Unsal, Ayse Ipek Akyuz; Hocaoglu, Mumin; Grp, T. R.-R.O.P. Study
Background To evaluate the prevalence, risk factors and treatment of retinopathy of prematurity (ROP) in Turkey and to establish screening criteria for this condition. Methods A prospective cohort study (TR-ROP) was performed between 1 April 2016 and 30 April 2017 in 69 neonatal intensive care units (NICUs). Infants with a birth weight (BW)=1500 g or gestational age (GA)<= 32 weeks and those with a BW> 1500 g or GA> 32 weeks with an unstable clinical course were included in the study. Predictors for the development of ROP were determined by logistic regression analyses. Results The TR-ROP study included 6115 infants: 4964 (81\%) with a GA <= 32 weeks and 1151 (19\%) with a GA>32 weeks. Overall, 27\% had any stage of ROP and 6.7\% had severe ROP. A lower BW, smaller GA, total days on oxygen, late-onset sepsis, frequency of red blood cell transfusions and relative weight gain were identified as independent risk factors for severe ROP in infants with a BW=1500 g. Of all infants, 414 needed treatment and 395 (95.4\%) of the treated infants had a BW <= 1500 g. Sixty-six (16\%) of the treated infants did not fulfil the Early Treatment for Retinopathy of Prematurity requirements for treatment. Conclusions Screening of infants with a GA <= 34 weeks or a BW<1700 g appears to be appropriate in Turkey. Monitoring standards of neonatal care and conducting quality improvement projects across the country are recommended to improve neonatal outcomes in Turkish NICUs.
Iris metastasis of gastric adenocarcinoma
(BMC, 2016-01-01) Celebi, Ali Riza Cenk; Kilavuzoglu, Ayse Ebru; Altiparmak, U. Emrah; Cosar, C. Banu; Ozkiris, Abdullah
Background: Iris metastasis in patients with gastric cancer is extremely rare. Herein, it is aimed to report on a patient with gastric adenocarcinoma and iris metastasis. Case presentation: A 65-year-old patient with the history of gastric cancer was admitted for eye pain and eye redness on his left eye. There was ciliary injection, severe +4 cells with hypopyon in the anterior chamber and a solitary, friable, yellow-white, fleshy-creamy vascularized 2 mm x 4 mm mass on the upper nasal part of the iris within the left eye. The presented patient's mass lesion in the iris fulfilled the criteria of the metastatic iris lesion's appearance. The ocular metastasis occurred during chemotherapy. Conclusions: Iris metastasis can masquerade as iridocyclitis with pseudohypopyon or glaucoma. In patients with a history of gastric cancer that present with an iris mass, uveitis, and high intraocular pressure, ocular metastasis of gastric cancer should be a consideration.
Predictive value of ectopic inner foveal layer without internal limiting membrane peeling for idiopathic epiretinal membrane surgery
(SPRINGER, 2022-01-01) Karasu, Bugra; Celebi, Ali Riza Cenk
Purpose To investigate the clinical importance of ectopic inner foveal layer (EIFL) grading (mild to severe) in patients diagnosed with idiopathic epiretinal membrane (iERM) and had pars plana vitrectomy (PPV) with solely ERM peeling. Materials and methods Patients diagnosed with iERMs who had undergone PPV including only ERM peeling were enrolled in the study, and follow-up findings were recorded at baseline, and at 3, 6, 12 months and final examinations. EIFL was categorized into four grades, from mild to severe. Pre- and postoperative anatomical changes were measured using spectral domain optical coherence tomography (SD-OCT) imaging. The association between EIFL and other SD-OCT parameters with best-corrected visual acuity (BCVA) was assessed before and after PPV surgery. Results One-hundred thirty-eight eyes of 106 patients with mild to severe EIFL were included in the study. Higher EIFL thickness was significantly correlated with lower baseline (r = 0.575, p = 0.020) and final BCVA (r = 0.748, p = 0.001). Although EIFLs continued in advanced-stage cases (stage 3 and 4) (64 eyes {[}82\%]) at the final visit, it was observed in 8 eyes (23\%) in the early stage (stage 2) of iERMs. A strong positive correlation was found between EIFL thickness and recurrence rate of ERM (r = 0.876, p < 0.001). Recurrence of ERM was detected in 27 eyes
Retinal tear: an unusual complication of ocular toxoplasmosis
(DE GRUYTER OPEN LTD, 2015-01-01) Celebi, Ali Riza Cenk; Kilavuzoglu, Ayse Ebru; Altiparmak, Ugur Emrah; Cosar, Cemile Banu; Ozkiris, Abdullah
Purpose: It is aimed to report on a 16-year-old patient with acquired ocular toxoplasmosis complicated by a retinal tear. Methods: Retrospective medical chart review Results: A 16-year-old Caucasian female presented with vision loss in her right eye. In addition to a white active lesion between the fovea and the optic nerve head, marked vitreous opacification was noted. She was diagnosed with ocular toxoplasmosis. The patient was treated with oral azithromycin, clindamycin, and trimethoprim-sulfamethoxazole. One month later, retinochoroiditis resolved and vitreous cleared. Three months after onset, patient presented with floaters in the right eye and a retinal tear was located at the temporal region of the retina. Prophylactic argon laser treatment that encircled the retinal tear was performed. No other abnormalities were noted during 6 months of follow-up. Conclusions: Retinal tear associated with ocular toxoplasmosis is rare
Structure-Function Mapping Using a Three-Dimensional Neuroretinal Rim Parameter Derived From Spectral Domain Optical Coherence Tomography Volume Scans
(ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2021-01-01) Celebi, Ali Riza Cenk; Park, Elli A.; Vercellin, Alice Chandra Verticchio; Tsikata, Edem; Lee, Ramon; Shieh, Eric; Antar, Hussein; Freeman, Madeline; Zhang, Jing; Que, Christian; Simavli, Huseyin; McClurkin, Michael; Guo, Rong; Elze, Tobias; de Boer, Johannes F.; Chen, Teresa C.
Purpose: To assess the structure-function relationship in glaucoma using Humphrey visual field (HVF) perinnetry and a three-dimensional neuroretinal rim parameter derived from spectral domain optical coherence tomography (SD-OCT) volume scans. Methods: Structure-function correlation was analyzed globally and regionally (four quadrants and four sectors). Structural data included peripapillary retinal nerve fiber layer (RNFL) thickness and minimum distance band (MDB) neuroretinal rim thickness, defined as the shortest distance between the inner cup surface and the outer retinal pigment epithelium/Bruch's membrane complex. Logarithmic regression analyses were performed and Pearson correlation coefficients determined to assess relationship strength. Results: The study consisted of 102 open-angle glaucoma patients and 58 healthy subjects. The Pearson correlation coefficient for global MDB thickness (R = 0.585) was higher than for global RNFL thickness (R = 0.492), but the difference was not statistically significant (P = 0.18). The correlation coefficients for regional MDB thicknesses and corresponding HVF sensitivities were higher than those for regional RNFL thicknesses and HVF in six out of eight regions (P = 0.08 to 0.47). In the remaining two out of eight regions, the correlation coefficients were higher for RNFL thickness than for MDB thickness (P = 0.15 to 0.20). Conclusions: Three-dimensional MDB neuroretinal rim thickness relates to visual function as strongly as the most commonly used SD-OCT parameter for glaucoma, two-dimensional peripapillary RNFL thickness. Translational Relevance: This paper illustrates the potential for 3D OCT algorithms to improve in vivo imaging in glaucoma.
The effect of hemodialysis on intraocular pressure
(WROCLAW MEDICAL UNIV, 2018-01-01) Kilavuzoglu, Ayse Ebru Bahadir; Yurteri, Gurkan; Guven, Nurgul; Marsap, Savas; Celebi, Ali Riza Cenk; Cosar, Cemile Banu
Background. The effect of hemodialysis (HD) on intraocular pressure (IOP) has been investigated before, but there is a lack of consensus. Clinicians dealing with renal failure patients are interested in the potential negative effects of HD on IOP and the course of glaucoma. Objectives. The aim of this study was to investigate the effects of HD on IOP in patients with end-stage renal disease. Material and methods. This prospective study included 106 patients who were receiving outpatient hemodialysis. Patient history of systemic and ophthalmologic conditions was recorded. Serum osmolality (mOsm), blood urea nitrogen (BUN), blood glucose (BG), bicarbonate (BC), and hematocrit (Hct) levels at the start of HD (pre-HD), at the end of HD (end-HD), and 30 min after HD (post-HD) were measured. Systolic and diastolic blood pressures (SBP and DBP) and IOP were measured at pre-HD, 1-hour intervals during HD, end-HD, and post-HD. Results. A significant decrease in mOsm and BUN and a significant increase in BG, BC, and Hct levels were observed at end-HD (p < 0.05). Mean IOP was 16.71 +/- 2.51 mm Hg at pre-HD, 15.52 +/- 3.18 mm Hg at end-HD, and 15.23 +/- 2.73 mm Hg at post-HD (p = 0.001
The Effect of Topical Ocular Anesthetic Proparacaine on Conjunctival and Nasal Mucosal Flora in Dry Eye Disease Patients
(MDPI, 2018-01-01) Celebi, Ozlem Onerci; Celebi, Ali Riza Cenk
The aim of this study was to investigate the effect of topically applied ocular anesthetic proparacaine on conjunctival and nasal bacterial mucosal flora in patients with dry eye disease. A Schirmer test was done with (group 1) and without (group 2) topical anesthetic proparacaine to 40 patients in each group. Conjunctival and nasal cultures were obtained before and 10 min after performing the Schirmer test. The bacterial culture results and the isolated bacteria were recorded in two groups. Patients' mean age was 62 years (70 female, 10 male). Before the application of topical anesthetic, 50 (62.5\%) and 62 (77.5\%) had positive conjunctival and nasal culture, respectively, with the most commonly isolated organism being coagulase-negative Staphylococcus in each group. In group 1 the conjunctival bacterial culture positivity rate decreased from 26 (65\%) to six (15\%) eyes (p < 0.001)
The effect of topical ocular moxifloxacin on conjunctival and nasal mucosal flora
(NATURE RESEARCH, 2021-01-01) Celebi, Ali Riza Cenk; Celebi, Ozlem Onerci
To determine the short-term effect of topically administered ocular moxifloxacin on conjunctival and nasal bacterial mucosal flora. The study included 20 patients with newly diagnosed age-related macular degeneration. Each patient's diseased eye was selected as the treatment eye and the fellow eye was selected as the control eye. All treatment eyes constituted the treatment group and all controls eyes constituted the control group. All patients received intravitreal injection of ranibizumab. Cultures were obtained from the inferior conjunctival fornix and the nostrils in all patients. Patients were instructed to administer moxifloxacin eye drops to the treatment eye 4 times daily for 1 week. The patients were instructed to come for a follow-up exam 1 week post intravitreal injection. The bacterial culture positivity rate and the bacteria isolated from the conjunctiva and nostrils were recorded in the 2 groups before and after use of topical ocular moxifloxacin. Mean age of the patients (12 female and 8 male) was 64.9 years. Before use of topical ocular moxifloxacin the conjunctival and nasal culture positivity rates in the treatment group were both 100\%, versus 90\% and 95\%, respectively, in the control group. At the follow-up exam the conjunctival and nasal mucosa culture positivity rates in the treatment group decreased to 20\% (4/20) and 30\% (6/20), respectively (P<0.001), versus 85\% (17/20) and 80\% (16/20), respectively, in the control group (P=0.68 and P=0.72 for conjunctival and nasal). This is the first study to show that moxifloxacin applied to the ocular surface topically has a significant effect on nasal flora. Daily administration of topical ocular moxifloxacin for 1 week significantly reduces the nasal bacterial flora in addition to conjunctival flora.
The role of anterior segment optical coherence tomography in the management of an intra-corneal foreign body
(SPRINGER INTERNATIONAL PUBLISHING AG, 2016-01-01) Celebi, Ali Riza Cenk; Kilavuzoglu, Ayse Ebru; Altiparmak, Ugur Emrah; Cosar, C. Banu; Ozkiris, Abdullah
Introduction: Corneal foreign bodies are reported to be the second most common type of ocular injury. Anterior segment optical coherence tomography (AS-OCT) is a valuable tool for the early diagnosis and monitoring the progress of treatment in cases of ocular trauma. Herein we aimed to report on a patient with an intra-corneal foreign body and the role of AS-OCT in management. Case presentation: A 34-year-old male presented with foreign body sensation in his left eye. Slit-lamp biomicroscopic examination revealed a peripherally located intrastromally embedded foreign body with a free anterior edge extending outwards from the cornea. It was not possible to visualize the foreign body's entire route through the cornea because of localized corneal edema. AS-OCT showed shadowing of the corneal layers corresponding to the location of the corneal foreign body. A hyper-reflective lesion was observed close to the inside edge of the foreign body in the cornea, indicating that the foreign body had not completely penetrated the cornea. The foreign body was removed via the external route, as it had not completely penetrated the cornea. During the postoperative period the patient was asymptomatic, although the left eye's cornea healed with scar tissue. Discussion and Evaluation: AS-OCT facilitates non-invasive rapid imaging of ocular tissue at various depths, thereby providing accurate assessment of foreign body characteristics. The location of an intracorneal foreign body and the status of the surrounding ocular structure dictate the optimal surgical technique to be employed. Conclusions: AS-OCT in the present case facilitated localization and determination of the size of a corneal foreign body. In addition, AS-OCT findings assisted in selection of the appropriate surgical intervention.