Browsing by Author "Demirci, Gulsen Tukenmez"

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A Case of Eccrine Porocarcinoma Accompanying Renal Cell Carcinoma
(GALENOS YAYINCILIK, 2021-01-01) Mansur, Ayse Tulin; Karsiyakali, Nejdet; Demirci, Gulsen Tukenmez; Koseoglu, Hikmet; Akman, Yavuz; Yildiz, Semsi
In this case report, we present the coexistence of eccrine porocarcinoma (EPC) and renal cell carcinoma (RCC) in a 69-year-old male patient whose surgical resection pathology of the skin lesion in the right gluteal region was reported as EPC and concurrent radical nephrectomy pathology of the right renal mass was reported as RCC.
A case of elephantiasis nostras verrucosa treated successfully by a new type of compressive garment
(WILEY, 2020-01-01) Mansur, A. Tulin; Ozker, Emre; Demirci, Gulsen Tukenmez
Elephantiasis nostras verrucosa (ENV) is a clinical manifestation composed of hyperkeratotic, verrucous, and papillomatous lesions and dermal fibrosis, which complicate chronic lymphedema. There is currently no cure for ENV, however, several measures have been used to reduce lymphedema and the resultant pseudoepidermal hyperplasia. Supportive dressings and compression therapy still constitute an important part of the treatment. In this report, we present a 69-year-old male patient with ENV developed due to chronic lymphedema caused by venous insufficiency. After failure of healing with conventional two- and three-layered bandages, and elastic stockings, he was successfully treated by a new type of compression garment. We recommend this user friendly garment for prevention of frictional trauma, contact dermatitis, and secondary infection, which all may complicate compression treatments.
An unusual lesion on the nose: microvenular hemangioma
(INT DERMOSCOPY SOCIETY, 2018-01-01) Mansur, A. Tulin; Demirci, Gulsen Tukenmez; Koc, Eltaf A. Ozbal; Yildiz, Semsi
Microvenular hemangioma (MVH) is an acquired, benign type of hemangioma that usually manifests itself as a solitary, slowly growing, red to violaceous, asymptomatic papule, plaque or nodule. It is typically located on the trunk or extremities of young adults. It can be difficult to differentiate MVH from other types of hemangioma and Kaposi sarcoma. Herein we report a case of MVH unusual for its location, age of onset, and morphologic features. A 62-year-old man complained of an asymptomatic, bluish-red discoloration on the tip of his nose that had been present for two years. Dermatologic examination showed a violaceous patch 2 x 2 cm in diameter with indistinct borders. Incisional biopsy revealed irregularly branched small or mediumsized vascular spaces lined with benign endothelial cells, positive for CD34 and negative for HHV-8. MVH is a rare lesion, and less than 70 cases have been published to date. A review of 40 reported cases revealed that 15\% of MVH patients were over 40 years of age and only 3\% of the cases showed macules or patches. A literature survey showed only two cases of MVH located on the facial region, one on the chin and the other on the cheek. Our case was unique for its location and interesting for other rarely encountered features. MVH should be considered in the differential diagnoses of vascular lesions on nasal skin.
Hepatitis C and hepatitis B virus infections in the etiopathogenesis of pemphigus
(SOC BRASILEIRA DERMATOLOGIA, 2014-01-01) Demirci, Gulsen Tukenmez; Aydingoz, Ikbal Esen; Mansur, Ayse Tulin; Atis, Guldehan; Altunay, Ilknur Kivanc
BACKGROUND: Previous studies have shown that some viral infections may be triggers for autoimmune diseases. The role of viral infections in the etiopathogenesis of pemphigus has also been investigated. OBJECTIVES: To investigate the relationship between pemphigus and the hepatitis B and C virus infections. METHODS: This retrospective study included 62 patients with pemphigus and 50 healthy controls of matching ages and genders. The control group included relatives who accompanied the orthopedic patients to the hospital but had no history of systemic and/or autoimmune diseases. RESULTS: The group of patients with pemphigus was composed of 43 (69.3\%) females and 19 (29.7\%) males, and the mean age was 48.08 +/- 15.38. The hepatitis C virus antibody was negative in all of the patients. Hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (HBsAb), or both, were studied in 44 of the 62 patients. Two (4.3\%) of these patients were positive for HBsAg and found to have HBV infection. Fourteen of them were HBsAb positive. Two (4\%) of the 50 control subjects showed hepatitis C virus antibody positivity, while only 1 (2\%) patient with pemphigus displayed HBsAg positivity. There was no statistically significant difference between the two groups for hepatitis B and C virus infections. CONCLUSIONS: This study does not support an association between pemphigus and hepatitis B and/or C virus infections.
Rapid onset acquired progressive kinking of the hair: Scanning electron microscopic findings in a woman
(SCIENTIFIC SCHOLAR LLC, 2021-01-01) Civas, Ekrem; Demirci, Gulsen Tukenmez
Risk Factors in Pemphigus
(DERI ZUHREVI HASTALIKLAR DERNEGI, 2011-01-01) Demirci, Gulsen Tukenmez; Mansur, Ayse Tulin; Aydingoz, Ikbal Esen
Background and Design: There have been reports suggesting the involvement of environmental factors in the disease process of pemphigus. In this study, we aimed to find out the risk factors which could play role in the etiopathogenesis in our pemphigus patients. Material and method: A total of 42 patients (15 male and 27 female) who were diagnosed as pemphigus with histopathological and direct immunoflurosence examinations in our clinic between the years 1998-2004, were interviewed for assessment of regarding with the subjects of the demographic properties, occupational groups, educational level, the number of pregnancies, stressfull life events, diet habits, smoking and alcohol consumption before the onset of the disease and the results were compared to 42 age and gender-matched controls with similar socioeconomic circumstances. Results: Working in agriculture and livestock, multi-parity, absence of smoking and stressfull life events were found to be statistically significant in pemphigus patients than in controls. Conclusion: Working in agriculture and livestock, multi-parity, absence of smoking and stressfull life events were assumed to play role in the etiopathogenesis and course of pemphigus. (Turkderm 2011