Browsing by Author "Erbey, Fatih"

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    Mesenchymal Stem Cell Treatment for Steroid Refractory Graft-versus-Host Disease in Children: A Pilot and First Study from Turkey
    (HINDAWI LTD, 2016-01-01) Erbey, Fatih; Atay, Didem; Akcay, Arzu; Ovali, Ercument; Ozturk, Gulyuz
    This study evaluated the efficacy of mesenchymal stem cells (MSCs) from bone marrow of a third-party donor for refractory aGVHD. We report the first experience using MSCs to treat refractory aGVHD in 33 pediatric patients undergoing allogeneic HSCT from Turkey. Totally, 68 doses of bone marrow derived MSCs were infused. The median dose of MSC was 1.18 x 10(6) cells per kg body weight. Overall, complete response (CR) was documented in 18 patients, partial response (PR) was documented in 7 patients, and no response (NR) was documented in 8 patients. The 2-year estimated probability of overall survival (OS) for patients achieving CR and PR/NR was 63.8\% and 29.4\%, respectively (p = 0.0002). While the cumulative incidence of transplant related mortality (TRM) at day 100 after first MSC infusion was 46.6\% in PR/NR patients, there was no any TRM at day 100 after first MSC infusion in CR patients (p = 0.001). Twelve patients developed chronic GVHD (cGVHD)
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    The Importance of Radiological Findings in Disseminated (Rhinocerebral and Pulmonary) Invasive Fungal İnfection with Childhood Acute Lymphoblastic Leukemia: Case Report.
    (Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2016-04-01) Erbey, Fatih; Bayram, İbrahim; Akgül, Erol; Tanyeli, Atila
    ABSTRACT The diagnosis of invasive fungal infection (IFI) is particularly difficult in immunocompromised patients. Clinical and radiological findings supporting the diagnosis of IFI are very important. We presented a case report to emphazise the radiological findings of IFI as a diagnostic tool in an acute lymphoblastic leukemia (ALL) patient with rhinocerebral and pulmonary IFI.