Browsing by Author "Gurel, Emre"

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Apical transverse motion is associated with speckle-tracking radial dyssynchrony in patients with non-ischemic dilated cardiomyopathy
(TURKISH SOC CARDIOLOGY, 2015-01-01) Gurel, Emre; Tigen, Kursat; Karaahmet, Tansu; Dundar, Cihan; Guler, Ahmet; Basaran, Yelda
Objective: Apical transverse motion (ATM) is a new parameter for assessing left ventricular (LV) dyssynchrony. Speckle-tracking radial strain analysis seems to be the best method to identify potential responders to cardiac resynchronization therapy. The aim of our study was to investigate the association between ATM and radial dyssynchrony assessed by speckle-tracking echocardiography in patients with non-ischemic dilated cardiomyopathy (NDC). Methods: We examined 35 NDC patients (mean age 49.2 +/- 28.1 years
Right ventricular function in hypertrophic cardiomyopathy: A speckle tracking echocardiography study
(TURKISH SOC CARDIOLOGY, 2015-01-01) Cincin, Altug; Tigen, Kursat; Karaahmet, Tansu; Dundar, Cihan; Gurel, Emre; Bulut, Mustafa; Sunbul, Murat; Basaran, Yelda
Objective: The aim of this study was to explore right ventricular (RV) mechanical function in patients with hypertrophic cardiomyopathy (HCM) by 2-D speckle tracking echocardiography (2-D-STE). Methods: Forty-three patients with HCM (mean age 48, 17 females) and 40 healthy subjects were consecutively included in this cross-sectional study. The diagnosis of HCM was based on the presence of typical clinical, electrocardiographic (ECG), and echocardiographic features. Patients with LV systolic impairment, significant valvular disease, history of coronary artery disease, hypertension, malignancy, and chronic obstructive pulmonary disease were excluded. Right and left ventricular (LV) function was assessed by tissue Doppler imaging (TDI) and 2-D-STE. Hypertrophic cardiomyopathy patients were divided into two groups according to ACC/ESC guidelines (LVOT gradient below and above 30 mm Hg). Student t-test was used to compare differences between groups. Non-parametric tests (Mann-Whitney U) were used in cases of abnormal distribution. Results: Hypertrophic cardiomyopathy patients had a significantly larger right atrium and RV diameters compared to controls. Mean pulmonary artery pressures (mPAB) were significantly higher in HCM patients (19.01 +/- 13.09 mm Hg vs. 8.40 +/- 4.50 mm Hg
The effect of myocardial fibrosis on left ventricular torsion and twist in patients with non-ischemic dilated cardiomyopathy
(VIA MEDICA, 2013-01-01) Karaahmet, Tansu; Gurel, Emre; Tigen, Kursat; Guler, Ahmet; Dundar, Cihan; Fotbolcu, Hakan; Basaran, Yelda
Background: Left ventricular (LV) rotation, twist, and torsion are important aspects of the cardiac performance. Myocardial fibrosis can be identified as the late gadolinium enhancement (LGE) in cardiac magnetic resonance (CMR). In this study, we investigated the association between myocardial fibrosis and LV rotational parameters in patients with nonischemic dilated cardiomyopathy (NDC). Methods: Twenty-two NDC patients were enrolled. LV dimensions, volumes and ejection fraction (EF) were measured, conventional tissue Doppler imaging data was acquired. Speckle tracking imaging was performed to measure LV deformation, LV rotational parameters. Blood samples were obtained for NT-proBNP. Late gadolinium enhanced cardiac magnetic resonance (LGE-CMR) was used to assess cardiac fibrosis index. Results: Myocardial deformation was similar between LGE+ and LGE-groups. LGE+ patients have significantly higher basal and lower apical systolic rotation, lower twist and torsion when compared to LGE-patients. However, untwisting rate was similar between the groups. Torsion was significantly correlated with LVEF and MR-index. Patients with reversed apical systolic rotation had significantly greater NT-proBNP values, basal systolic rotation and significantly lower apical systolic rotation, torsion, and MR-index. Conclusions: Cardiac fibrosis index is closely related with myocardial torsion and LV systolic function and may be used for the evaluation of cardiac condition. Reversed apical systolic rotation indicated more extensive cardiac fibrosis as it may reflect severe LV dyssynchrony and poor LV performance.