Browsing by Author "Kisacik, Halil Lutfi"
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Item Association of Prediabetes with Diffuse Coronary Narrowing and Small-Vessel Disease(2013-01-01) Gul, Murat; Ertan, Cagatay; Ozeke, Ozcan; Aras, Dursun; Topaloglu, Serkan; Kisacik, Halil Lutfi; Demir, Ahmet Duran; Aydogdu, Sinan; Ozin, BulentItem Association of prediabetes with diffuse coronary narrowing and small-vessel disease(ELSEVIER, 2014-01-01) Ertan, Cagatay; Ozeke, Ozcan; Gul, Murat; Aras, Dursun; Topaloglu, Serkan; Kisacik, Halil Lutfi; Demir, Ahmet Duran; Aydogdu, Sinan; Ozin, BulentBackground: A significant number of patients may not benefit from conventional techniques of myocardial revascularization due to diffuse coronary artery disease (CAD) or small coronary arterial sizes because of smaller arteries causing anastomotic technical difficulties and poor run-off. Diabetic patients have a more severe and diffuse coronary atherosclerosis with smaller coronary arteries limiting the possibility to perform a successful and complete revascularization, but this has not been examined in prediabetics. Objective: To evaluate whether there is an association between prediabetes and the coronary arterial size. Methods: We prospectively studied 168 consecutive patients with CAD and 172 patients with normal coronary artery anatomy (NCA). Patients were divided into three groups according to hemoglobin (Hb) A1c levels as ``normal,{''} ``prediabetic,{''} and ``diabetic{''} groups, and the coronary artery sizes and Gensini scores were analyzed. Results: There were 78 female patients and 90 male patients in the CAD group, and 87 female patients and 85 male patients in the NCA group. There was a statistically significant difference in distal and proximal total coronary arterial size among the CAD and NCA groups for both genders. There was a positive correlation between the HbA1c subgroups and Gensini score (Spearman's rho: 0.489, p < 0.001 in female group