Browsing by Author "Kurtulmus, Neslihan"

Filter results by typing the first few letters
Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    BRAF(V600E) Mutation: Has It a Role in Cervical Lymph Node Metastasis of Papillary Thyroid Cancer?
    (KARGER, 2016-01-01) Kurtulmus, Neslihan; Ertas, Burak; Saglican, Yesim; Kaya, Hakan; Ince, Umit; Duren, Mete
    Background: The BRAF(V600E) mutation is common in papillary thyroid cancer (PTC). Lymph node metastasis (LNM) may be associated with poor prognosis. However, the LNM mechanism remains unclear. Objectives: Our aim was to evaluate the prevalence of the BRAF(V600E) mutation in primary tumors and accompanying LNM at the time of diagnosis. Methods: This retrospective study included 51 PTC patients (40 women, 11 men
  • No Thumbnail Available
    Item
    Coexisting atrial fibrillation and paralysis as a result of hypokalemia in a Caucasian man with Graves' disease
    (ELSEVIER SCIENCE BV, 2013-01-01) Kurtulmus, Neslihan; Celik, Seden Erten
    A 29-year-old Caucasian man with a history of Graves' disease for 6 weeks presented to our emergency department at midnight with muscle weakness. He had woken up after 1e2 hours of sleep with weakness in his lower extremities. Electrocardiography (ECG) showed atrial fibrillation. His potassium level was 2.6 mEq/L. His ECG was monitored, and potassium chloride mixed with a normal saline infusion (20 mEq/L) was given for 1 hour. After his potassium level returned to normal (4.63 mEq/L), clinical improvement was noted. The ECG showed sinus rhythm. Clinicians should consider thyrotoxic periodic paralysis in patients with hypokalemia and paralysis, even though it is rare in Caucasians. Copyright (C) 2013, Taiwan Society of Emergency Medicine. Published by Elsevier Taiwan LLC. All rights reserved.
  • No Thumbnail Available
    Item
    Expression of vascular endothelial growth factor in follicular cell-derived lesions of the thyroid: Is NIFTP benign or precancerous?
    (TURKISH SURGICAL ASSOC, 2022-01-01) Kurtulmus, Neslihan; Tokat, Fatma; Duren, Mete; Kaya, Hakan; Ertas, Burak; Ince, Umit
    Objective: Vascular endothelial growth factor (VEGF) is an angiogenic factor that plays an important role in physiological and pathological angiogenesis of the thyroid. The aim of the current study was to determine the expression characteristics of VEGF in follicular cell-derived lesions of the thyroid and to assess whether a new entity noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is precancerous. Material and Methods: Patients diagnosed with 33 follicular adenomas (FA), 41 invasive follicular variant papillary thyroid cancer (IN-FVPTC), and 40 NIFTP in surgical resection materials were evaluated retrospectively. Immunostaining was performed on 5-mu m paraffin tissue sections. The percentages of immunostaing for VEGF were evaluated on pathological materials. We used a percentage of labeled thyrocytes score (0, no labeling