Browsing by Author "Sariguzel, Nevin"

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Association between renin-angiotensin-aldosterone system inhibitor treatment, neutrophil-lymphocyte ratio, D-Dimer and clinical severity of COVID-19 in hospitalized patients: a multicenter, observational study
(SPRINGERNATURE, 2021-01-01) Gormez, Selcuk; Ekicibasi, Erkan; Degirmencioglu, Aleks; Paudel, Ashok; Erdim, Refik; Gumusel, Hilal Kurtoglu; Eroglu, Elif; Tanboga, Ibrahim Halil; Dagdelen, Sinan; Sariguzel, Nevin; Kirisoglu, Ceyda Erel; Pamukcu, Burak
The aim of this study was to investigate the possible relationship between worse clinical outcomes and the use of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) in hospitalized COVID-19 patients. A total of 247 adult patients (154 males, 93 females
Atypical presentation of SARS-CoV-2 infection in male genitalia
(ELSEVIER SCIENCE INC, 2020-01-01) Ozveri, Hakan; Eren, Murat Tugrul; Kirisoglu, Ceyda Erel; Sariguzel, Nevin
During novel coronavirus 2019 (COVID-19) pandemic, patients usually present with several reports showing symptoms of severe systemic or respiratory illness and, although rare, some genital complaints such as scrotal discomfort can be seen. In the majority of patients, however, genital complaints seem not to be the initial or sole symptoms. In this article, we report an unusual presentation of a male case with severe external genital pain which was suspected to be the first clinical sign of COVID-19.
Comparison of hypertension prevalence and the use of renin-angiotensin-aldosterone system blockers in hospitalized patients with COVID-19 and non-COVID-19 viral pneumonia
(AVES, 2021-01-01) Gormez, Selcuk; Kirisoglu, Ceyda Erel; Ekicibasi, Mehmet Erkan; Degirmencioglu, Aleks; Paudel, Ashok; Akan, Gokce; Atalar, Fatmahan; Sariguzel, Nevin; Pamukcu, Burak
Objective: To compare the prevalence of hypertension and pre-existing use of renin-angiotensin-aldosterone system blockers in patients with coronavirus disease (COVID-19) and non-COVID-19 viral pneumonias. Methods: Real-time polymerase chain reaction confirmed COVID-19 and non-COVID-19 pneumonia patients were retrospectively analyzed. The presence of hypertension, coronary artery disease (CAD), and pre-existing use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) were compared between the groups. Results: A total of 103 COVID-19 and 91 non-COVID-19 hospitalized viral pneumonia patients were enrolled. Hypertension and CAD were more common in patients with non-COVID-19 viral pneumonia than in patients with COVID-19 (39.6\% vs 22.3\%, respectively, p=0.012 and 24.2\% vs 4.9\%, respectively, p<0.001). In our study, 2.9\% and 6.8\% of patients with COVID-19 were on ACEIs and ARBs, respectively, whereas 13.2\% and 19.8\% of patients with non-COVID-19 viral pneumonia were on ACEIs and ARBs, respectively (p=0.009 and p=0.013). Neutrophil-to-lymphocyte ratio (p<0.001) was prominent in patients with non-COVID-19 viral pneumonia compared with patients with COVID-19. Conclusion: Our study results indicate that hypertension and CAD are more common among patients with non-COVID-19 viral pneumonia than patients with COVID-19. The prevalence of ACEIs and ARBs use was not higher in patients with COVID-19. Our results support that the use of ACEIs and ARBs do not play a specific role in patients with COVID-19.
Dobrava Hantavirus Infection Complicated by Panhypopituitarism, Istanbul, Turkey, 2010
(CENTERS DISEASE CONTROL, 2012-01-01) Sariguzel, Nevin; Hofmann, Joerg; Canpolat, Alper Tunga; Turk, Ali; Ettinger, Jakob; Atmaca, Deniz; Akyar, Isin; Yucel, Serap; Arikan, Ender; Uyar, Yavuz; Caglayik, Dilek Y.; Kocagoz, Ayse Sesin; Kaya, Aysin; Kruger, Detlev H.
We identified Dobrava-Belgrade virus infection in Turkey (from a strain related to hantavirus strains from nearby countries) in a patient who had severe symptoms leading to panhypopituitarism, but no known risk for hantavirus. Our findings emphasize the need for increased awareness of hantaviruses in the region and assessment of symptomatic persons without known risk factors for infection.