Browsing by Author "Sonmez, Erkin"

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    Prognostic Impact of Histologic Subtype in Non-Small Cell Lung Cancer Patients Treated with Gamma Knife Radiosurgery: Retrospective Analysis of 104 Patients
    (TURKISH NEUROSURGICAL SOC, 2017-01-01) Aydemir, Fatih; Tufan, Kadir; Cekinmez, Melih; Kardes, Ozgur; Sarica, Feyzi Birol; Topkan, Erkan; Sonmez, Erkin; Alkan, Ozlem; Ugurluer, Gamze; Altinors, Nur
    AIM: In this study, factors affecting survival, local failure, distant brain failure, whole brain failure and whole-brain radiation therapy (WBRT) free survival according to histological subtypes were investigated in patients with brain metastases from non-small cell lung cancer (NSCLC). MATERIAL and METHODS: Patients with positive pathology reports for adenocarcinoma (ACA) and squamous cell carcinoma (SCC) were included in the study. Seventy-eight ACA and 26 SCC patients were included in the study. Patients with previous history of cerebral metastasis surgery and WBRT were excluded from the study. RESULTS: The median survival was calculated as 12.6 months for patients with ACA and 5.9 months for patients with SCC. One-year distant brain failure was calculated as 65.1\% in ACA patients and 39.6\% in SCC patients. One-year whole brain failure was calculated as 58.1\% in ACA patients and 39.6\% in SCC patients. The one-year freedom from WBRT rate was calculated as 72.8\% in ACA patients and 56.3\% in SCC patients. SCC histology was considered as a significant factor in deterioration of overall survival in multivariate analysis. SCC histology, the increase in the number of metastases and RPA class were factors that caused an increase in distant brain failure. Also, SCC histology, the increase in the number of metastases and RPA class were factors that caused an increase in whole brain failure. CONCLUSION: SCC histology may be an important prognostic factor for overall survival. Also, due to high distant brain failure rate in SCC histology, WBRT can be added to treatment early.
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    The Global Spine Care Initiative: care pathway for people with spine-related concerns
    (SPRINGER, 2018-01-01) Haldeman, Scott; Johnson, Claire D.; Chou, Roger; Nordin, Margareta; Cote, Pierre; Hurwitz, Eric L.; Green, Bart N.; Cedraschi, Christine; Acaroglu, Emre; Kopansky-Giles, Deborah; Ameis, Arthur; Adjei-Kwayisi, Afua; Ayhan, Selim; Blyth, Fiona; Borenstein, David; Brady, O'Dane; Brooks, Peter; Camilleri, Connie; Castellote, Juan M.; Clay, Michael B.; Davatchi, Fereydoun; Dunn, Robert; Goertz, Christine; Griffith, Erin A.; Hondras, Maria; Kane, Edward J.; Lemeunier, Nadege; Mayer, John; Mmopelwa, Tiro; Modic, Michael; Moss, Jean; Mullerpatan, Rajani; Muteti, Elijah; Mwaniki, Lillian; Ngandeu-Singwe, Madeleine; Outerbridge, Geoff; Randhawa, Kristi; Shearer, Heather; Sonmez, Erkin; Torres, Carlos; Torres, Paola; Verville, Leslie; Vlok, Adriaan; Watters III, William; Wong, Chung Chek; Yu, Hainan
    Purpose The purpose of this report is to describe the development of an evidence-based care pathway that can be implemented globally. Methods The Global Spine Care Initiative (GSCI) care pathway development team extracted interventions recommended for the management of spinal disorders from six GSCI articles that synthesized the available evidence from guidelines and relevant literature. Sixty-eight international and interprofessional clinicians and scientists with expertise in spine-related conditions were invited to participate. An iterative consensus process was used. Results After three rounds of review, 46 experts from 16 countries reached consensus for the care pathway that includes five decision steps: awareness, initial triage, provider assessment, interventions (e.g., non-invasive treatment
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    The Global Spine Care Initiative: classification system for spine-related concerns
    (SPRINGER, 2018-01-01) Haldeman, Scott; Johnson, Claire D.; Chou, Roger; Nordin, Margareta; Cote, Pierre; Hurwitz, Eric L.; Green, Bart N.; Kopansky-Giles, Deborah; Cedraschi, Christine; Aartun, Ellen; Acaroglu, Emre; Ameis, Arthur; Ayhan, Selim; Blyth, Fiona; Borenstein, David; Brady, O'Dane; Davatchi, Fereydoun; Goertz, Christine; Hajjaj-Hassouni, Najia; Hartvigsen, Jan; Hondras, Maria; Lemeunier, Nadege; Mayer, John; Mior, Silvano; Mmopelwa, Tiro; Modic, Michael; Mullerpatan, Rajani; Mwaniki, Lillian; Ngandeu-Singwe, Madeleine; Outerbridge, Geoff; Randhawa, Kristi; Sonmez, Erkin; Torres, Carlos; Torres, Paola; Watters III, William; Yu, Hainan
    Purpose The purpose of this report is to describe the development of a classification system that would apply to anyone with a spine-related concern and that can be used in an evidence-based spine care pathway. Methods Existing classification systems for spinal disorders were assembled. A seed document was developed through round-table discussions followed by a modified Delphi process. International and interprofessional clinicians and scientists with expertise in spine-related conditions were invited to participate. Results Thirty-six experts from 15 countries participated. After the second round, there was 95\% agreement of the proposed classification system. The six major classifications included: no or minimal symptoms (class 0)
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    The Global Spine Care Initiative: methodology, contributors, and disclosures
    (SPRINGER, 2018-01-01) Johnson, Claire D.; Haldeman, Scott; Nordin, Margareta; Chou, Roger; Cote, Pierre; Hurwitz, Eric L.; Green, Bart N.; Kopansky-Giles, Deborah; Randhawa, Kristi; Cedraschi, Christine; Ameis, Arthur; Acaroglu, Emre; Aartun, Ellen; Adjei-Kwayisi, Afua; Ayhan, Selim; Aziz, Amer; Bas, Teresa; Blyth, Fiona; Borenstein, David; Brady, O'Dane; Brooks, Peter; Camilleri, Connie; Castellote, Juan M.; Clay, Michael B.; Davatchi, Fereydoun; Dudler, Jean; Dunn, Robert; Eberspaecher, Stefan; Emmerich, Juan; Farcy, Jean Pierre; Fisher-Jeffes, Norman; Goertz, Christine; Grevitt, Michael; Griffith, Erin A.; Hajjaj-Hassouni, Najia; Hartvigsen, Jan; Hondras, Maria; Kane, Edward J.; Laplante, Julie; Lemeunier, Nadege; Mayer, John; Mior, Silvano; Mmopelwa, Tiro; Modic, Michael; Moss, Jean; Mullerpatan, Rajani; Muteti, Elijah; Mwaniki, Lillian; Ngandeu-Singwe, Madeleine; Outerbridge, Geoff; Rajasekaran, Shanmuganathan; Shearer, Heather; Smuck, Matthew; Sonmez, Erkin; Tavares, Patricia; Taylor-Vaisey, Anne; Torres, Carlos; Torres, Paola; van der Horst, Alexander; Verville, Leslie; Vialle, Emiliano; Kumar, Gomatam Vijay; Vlok, Adriaan; Watters III, William; Wong, Chung Chek; Wong, Jessica J.; Yu, Hainan; Yuksel, Selcen
    Purpose The purpose of this report is to describe the Global Spine Care Initiative (GSCI) contributors, disclosures, and methods for reporting transparency on the development of the recommendations. Methods World Spine Care convened the GSCI to develop an evidence-based, practical, and sustainable healthcare model for spinal care. The initiative aims to improve the management, prevention, and public health for spine-related disorders worldwide
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    The Global Spine Care Initiative: model of care and implementation
    (SPRINGER, 2018-01-01) Johnson, Claire D.; Haldeman, Scott; Chou, Roger; Nordin, Margareta; Green, Bart N.; Cote, Pierre; Hurwitz, Eric L.; Kopansky-Giles, Deborah; Acaroglu, Emre; Cedraschi, Christine; Ameis, Arthur; Randhawa, Kristi; Aartun, Ellen; Adjei-Kwayisi, Afua; Ayhan, Selim; Aziz, Amer; Bas, Teresa; Blyth, Fiona; Borenstein, David; Brady, O'Dane; Brooks, Peter; Camilleri, Connie; Castellote, Juan M.; Clay, Michael B.; Davatchi, Fereydoun; Dudler, Jean; Dunn, Robert; Eberspaecher, Stefan; Emmerich, Juan; Farcy, Jean Pierre; Fisher-Jeffes, Norman; Goertz, Christine; Grevitt, Michael; Griffith, Erin A.; Hajjaj-Hassouni, Najia; Hartvigsen, Jan; Hondras, Maria; Kane, Edward J.; Laplante, Julie; Lemeunier, Nadege; Mayer, John; Mior, Silvano; Mmopelwa, Tiro; Modic, Michael; Moss, Jean; Mullerpatan, Rajani; Muteti, Elijah; Mwaniki, Lillian; Ngandeu-Singwe, Madeleine; Outerbridge, Geoff; Rajasekaran, Shanmuganathan; Shearer, Heather; Smuck, Matthew; Sonmez, Erkin; Tavares, Patricia; Taylor-Vaisey, Anne; Torres, Carlos; Torres, Paola; van der Horst, Alexander; Verville, Leslie; Vialle, Emiliano; Kumar, Gomatam Vijay; Vlok, Adriaan; Watters III, William; Wong, Chung Chek; Wong, Jessica J.; Yu, Hainan; Yuksel, Selcen
    Purpose Spine-related disorders are a leading cause of global disability and are a burden on society and to public health. Currently, there is no comprehensive, evidence-based model of care for spine-related disorders, which includes back and neck pain, deformity, spine injury, neurological conditions, spinal diseases, and pathology, that could be applied in global health care settings. The purposes of this paper are to propose: (1) principles to transform the delivery of spine care