Browsing by Author "Topcu, Deniz Ilhan"

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    Comparison of classical and clustering based reference interval calculations for Aspartate Aminotransferase, Alanine Aminotransferase and Gamma-Glutamyl Transferase in serum
    (WALTER DE GRUYTER GMBH, 2015-01-01) Cosgun, Erdal; Topcu, Deniz Ilhan; Laleli, Yahya
    Objective: There are fixed rules applied to determine the reference intervals (RIs) of the biochemical tests. However, these rules lack for identifying subgroups within the reference population. Therefore, we suggest the clustering method, which determines the sub-groups by taking the correlations between the variables into account in the RIs calculations. In our study, it is aimed to compare the results of the RIs based on the clusters analysis with the results of the conventional method. Methods: The individuals who applied Ankara Duzen Laboratory for the check-up with normal Ultra Sono Grafi (USG) in 2012-2014 and who have had Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT) and G-Glutamyl Transferase (GGT)