Browsing by Author "Yalin, Aymelek"

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    Early Onset of Atherosclerosis of The Carotid Bifurcation in Newborn Cadavers
    (PREMCHAND SHANTIDEVI RESEARCH FOUNDATION, 2016-01-01) Uslu, Bahar; Cakmak, Yusuf Ozgur; Sehirli, Umit; Keskinoz, Elif Nedret; Cosgun, Erdal; Arbak, Serap; Yalin, Aymelek
    Introduction: The anatomy of arterial bifurcations affects blood flow and has a significant role in the development of vascular disease. Therefore, it is important to know the structural characteristics of the Common Carotid Artery (CCA) and its branches for early onset of atherosclerosis in newborns. Aim: The present study was conducted to evaluate the characteristics of CCA in newborn cadavers. Materials and Methods: Eight carotid arteries obtained from newborn cadavers were used. The outflow to inflow area ratios was calculated to evaluate vessel diameters. Additionally, scanning electron and light microscopic investigations were conducted with tissue samples. The brachial artery of each cadaver was used as controls. Correlation between area ratios and atherosclerotic endothelial damage was determined. Results: Light microscopic investigations demonstrated that control group sections showed no positivity for Oil red O staining, while carotid bifurcation regions depicted widespread occurrence of intimal lipid accumulations. Scanning electron microscopic examination of control group sections presented regular endothelial topography, while carotid bifurcation region topography exhibited numerous blood cells and separated endothelial cells. Fibrin accumulation on endothelial surface in low area ratios was another important finding in the examination of its endothelial surface degeneration. The above-mentioned morphological findings seemed to be quite parallel to outflow to inflow area ratio data favouring low area and degeneration. Conclusion: The correlation between area ratios and the histological characteristic of cerebral vessels of newborn cadavers indicate that early stages of atherosclerosis began in early embryologic life.
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    Morphologic Characteristics of Meniscofemoral Ligaments
    (ORTADOGU AD PRES \& PUBL CO, 2011-01-01) Sozmen, Aycan Guclu; Yalin, Aymelek; Uzun, Ibrahim; Sehirli, Umit Suleyman
    Objective: The aim of this study was to describe the presence, lengths, widths, attachment sites, course of the fibers, histological properties and the sizes of the attachment sites of the meniscofemoral ligaments to the lateral meniscus. Material and Methods: Forty fresh frozen knees obtained from 22 human cadavers were examined. The knee was dissected by posterior approach and the anterior and posterior meniscofemoral and posterior cruciate ligaments were measured after exposing them. The sections of ligaments were stained with the Mason trichrome stain and under light microscope. Results: At least one of the meniscofemoral ligaments was present in 37 (92.5\%) cases. Twenty (50\%) were anterior meniscofemoral ligaments and 24(60\%) were posterior. In seven cases (17.5\%) both anterior and posterior meniscofemoral ligaments were present. The oblique fibers of the posterior cruciate ligament were observed in 11 (27.5\%) cases. A separating membrane between the meniscofemoral ligaments and the posterior cruciate ligament was observed. The mean lengths of the posterior and anterior meniscofemoral ligaments were 23.82 +/- 1.51 mm and 21.55 +/- 0.97 mm, respectively. The mean widths of the anterior and posterior meniscofemoral ligaments were 3.43 +/- 0.57 mm and 4.09 +/- 0.77 mm, respectively. The mean lengths of the attachment sites of posterior and anterior meniscofemoral ligaments to lateral meniscus were 11.30 +/- 1.85 mm and 6.19 +/- 1.23 mm respectively and the mean widths were 3.39 +/- 0.92 mm and 4.88 +/- 0.96 mm, respectively. Conclusion: Details concerning the dimensions and histological properties of the meniscofemoral ligaments, their relation to the posterior cruciate ligament and lateral meniscus will contribute to a clear understanding of the biomechanics of the knee as well as the radiologic diagnosis and the treatment of knee problems.