Browsing by Author "Yilmaz, Mehmet"

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Comparison of outcomes of Holmium enucleation of the prostate for small- and moderate-sized prostates
(WILEY, 2021-01-01) Yilmaz, Sercan; Yalcin, Serdar; Yilmaz, Mehmet; Acikgoz, Onur; Aybal, Halil cagri; Gazel, Eymen; Kaya, Engin; Tunc, Lutfi
There is an ongoing discussion in the literature on the surgical treatment option for small prostate size benign prostate hyperplasia (BPH) patients. This study aimed to evaluate the efficacy of Holmium laser enucleation of the prostate (HoLEP) surgery in small (<30 ml) and moderate (30-80 ml) prostate size as accepted in European Association of Urology guideline. We retrospectively analysed our database between May 2016 and May 2019 and patients who underwent HoLEP surgery. Patients who have prostate size <80 ml were included the study. These patients were divided into two group: group 1 with prostate size <30 ml (n: 64) and group 2 with prostate size 30-80 ml (n: 101). Enucleation time (ET), morcellation time (MT), total operation time (OT), enucleation efficiency (EE), morcellation efficiency (ME), intra- and post-operative complications were analysed. While EE and Hb drop were better in favour of group 2
Decellularization of Trachea With Combined Techniques for Tissue-Engineered Trachea Transplantation
(KOREAN SOC OTORHINOLARYNGOL, 2019-01-01) Batioglu-Karaaltin, Aysegul; Ovali, Ercument; Karaaltin V, Mehmet; Yener, Murat; Yilmaz, Mehmet; Epupoglu, Fatma; Yilmaz, Yetkin Zeki; Bozkurt, Erol Rustu; Demir, Necdet; Konuk, Esma; Bozdag, Ergun Sureyya; Yigit, Ozgur; Cansiz, Harun
Objectives. The purpose of this study is to shorten the decellularization time of trachea by using combination of physical, chemical, and enzymatic techniques. Methods. Approximately 3.5-cm-long tracheal segments from 42 New Zealand rabbits (3.5 +/- 0.5 kg) were separated into seven groups according to decellularization protocols. After decellularization, cellular regions, matrix and strength and endurance of the scaffold were followed up. Results. DNA content in all groups was measured under 50 ng/mg and there was no significant difference for the glycosaminoglycan content between group 3 (lyophilization+deoxycholic acid+de-oxyribonuclease method) and control group (P=0.46). None of the decellularized groups was different than the normal trachea in tensile stress values (P>0.05). Glucose consumption and lactic acid levels measured from supernatants of all decellularized groups were close to group with cells only (76 mg/dl, and 53 mg/L). Conclusion. Using combination methods may reduce exposure to chemicals, prevent the excessive influence of the matrix, and shorten the decellularization time.
Impact of diabetes mellitus on urinary continence after holmium laser enucleation of the prostate due to lower urinary tract symptoms: a retrospective study
(POLISH UROLOGICAL ASSOC, 2021-01-01) Acikgoz, Onur; Yilmaz, Mehmet; Aybal, Halil Cagri; Yilmaz, Sercan; Gazer, Eymen; Yalcin, Serdar; Duvarci, Mehmet; Kaya, Engin; Miernik, Arkadiusz; Tunc, Lutfi
Introduction Diabetes mellitus (DM) is known as a risk factor of stress urinary incontinence after Holmium laser enucleation of the prostate (HoLEP). We aimed to compare the postoperative continence status of patients with and without DM, after HoLEP surgery. Material and methods A total of 214 patients who underwent HoLEP between January 2017 and January 2020 were retrospectively assessed. Functional outcomes, perioperative total operation time (TOT) (min), enucleation time (ET)(min), enucleation efficiency (EE)(g/min), enucleated tissue weight (ETW)(g), morcellation efficiency (ME)(g/min), morcellation time (MT)(min), continence status, intraoperative and postoperative complications according to Clavien-Dindo classification were recorded. Results A total of 96 patients had DM additional to benign prostate hyperplasia (BPH) (Group 1), while 118 patients had only benign prostate hyperplasia without DM (Group 2). When comparing preoperative and postoperative functional outcomes, a statistically significant improvement was observed in both groups from baseline to the 1st and 6th month follow-up (p <= 0.001). There were no statistically significant differences between groups in postoperative stress urinary incontinence at postoperative months 1 and 6 (1.7\% vs 2.1\%, p = 1 and 0.8\% vs 1\%, p = 1
Laser enucleation for prostates larger than 100 mL: Comparison of HoLEP and ThuLEP
(WILEY, 2021-01-01) Kaya, Engin; Yilmaz, Sercan; Acikgoz, Onur; Aybal, Halil Cagri; Yilmaz, Mehmet; Gazel, Eymen; Yalcin, Serdar; Suarez-Ibarrola, Rodrigo; Tunc, Lutfi
Recently, with the advancements in laser technology, Holmium laser enucleation of the prostate (HoLEP) and Thulium laser enucleation of the prostate (ThuLEP) have come to the fore in the surgical treatment of benign prostatic hyperplasia (BPH). We aimed to evaluate and compare the outcomes of HoLEP and ThuLEP in patients with >100 ml prostate volume. Patients who underwent HoLEP and ThuLEP between July 2017 and March 2020 were reviewed retrospectively. The patients were divided into two groups as HoLEP (Group 1, n = 121) and ThuLEP (Group 2, n = 104). Perioperative parameters, functional outcomes, continence status, intra and post-operative complications were compared between groups in the post-operative 1st and 6th month. No significant difference was found in terms of total laser energy (TLE), morcellation efficiency (ME), enucleated tissue weight (ETW), complication rates (CR) and continence status of patients between both groups (p > .05). In favour of ThuLEP group, there were statistically significant differences regarding total operation time (TOT), laser efficiency (LE), enucleation time (ET) and enucleation efficiency (EE) between groups (p <= .05). HoLEP and ThuLEP can be used safely and effectively in prostates larger than 100 ml.