Araştırma Makaleleri
Permanent URI for this collectionhttps://hdl.handle.net/11443/548
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Item Assessment of the Relationship between University Students’ Food Consumption and Anthropometric Measurements and Phase Angle(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2022-01-01) Ekici, Merve; Arıtıcı Çolak, GözdeABSTRACT Purpose: This study was carried out to assess the relationship between university students’ food consumption and anthropometric measurements, and phase angle (PA). Methods: The study was conducted with a total of 240 students between the ages of 18-25 studying at the Department of Nutrition and Dietetics at Agri Ibrahim Cecen University Health School. Research data were collected using a questionnaire that included about demographic information and questions about physical activity levels and three day food consumption record was taken. Lastly, anthropometric measurements of the students were performed by the researcher in person. Results: The study’s findings revealed that the students’ energy intake was lower than their energy expenditures. The body mass indexes (BMI), and waist circumferences of female and male students were calculated as 21.8 ± 3.2 kg/m2 and 23 ± 3.4 kg/m2 , and 75.2 ± 8.1 cm and 85 ± 10 cm, respectively. The PA was 5.7 ± 0.5º in female students and 6.7 ± 0.5º in male students (p<0.05). Conclusion: The study’s findings revealed that male students had significantly higher PA values. The PA values of female students were found to have increased with BMI, waist circumference, and body muscle mass values. There was also no significant relationship between students’ PA values and and food consumption levels regardless of gender.Item The Efficacy of Low-Dose Enoxaparin in Psoriasis(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2022-01-01) Demircioğlu, Deniz; Atakan, NilgünABSTRACT Psoriasis is a frequently encountered inflammatory skin disease with unclear etiology and no curative therapy. Enoxaparin is a low-molecular weight heparin analogue. Heparin and its analogues in low doses have antiproliferative and immunomodulatory effects. Low-dose enoxaparin has inhibitory effects on T cell-mediated immune reactions. T lymphocytes play a key role in the immunopathogenesis of psoriasis. The aim of this study was to evaluate the efficacy of low-dose enoxaparin in the treatment of psoriasis. Twenty-three patients with chronic plaque and guttate psoriasis were enrolled in an open study. Patients were given subcutaneous injections of 5 mg enoxaparin once weekly for a total of 6 weeks. There was a statistically significant difference between the PASI (Psoriasis Area and Severity Index) scores at the beginning and at the 6th week follow up (p=0.008). Four out of 23 patients (17%) showed marked improvement (≥50% reduction in PASI score), 8 patients (35%) showed moderate improvement (25-49% reduction in PASI score), 5 patients (22%) were unchanged (<25% reduction in PASI score). Six patients (26%) experienced worsening with a corresponding increase in the PASI scores. Based on these findings, 52% of patients were considered to get benefit from enoxaparin treatment. No systemic side-effects due to enoxaparin were observed. The only local side-effect recorded in 7 patients (30%) was ecchymosis at the injection site. Low-dose enoxaparin, which appears to be safe, is a candidate to become a future alternative in the treatment of psoriasis. Further studies assessing the optimum dose and duration of treatment, as well as patient subgroups that will benefit most from enoxaparin treatment are warranted. In addition, efficacy of enoxaparin in psoriasis should be compared to those of standard therapeutic modalities.Item Effects of Anemia on Clinical Outcomes in Hospitalized Patients with COVID-19 Pneumonia(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2022-01-01) Kurtoğlu Gümüşel, Hilal; Görmez, Selçuk; Özçağlayan, Ömer; Pamukçu, BurakBSTRACT Objective: We aimed to examine the role of anemia on clinical outcomes including intensive care unit (ICU) admission and mechanical ventilation (MV) in coronavirus disease 2019 (COVID-19) patients. Materials and methods: Totally 175 hospitalized COVID-19 patients were retrospectively included. Patients with a hemoglobin level of <12 g/dL in women and <13 g/dL in men constituted the anemic group, while COVID-19 patients with normal hemoglobin levels constituted the non-anemic group. A logistic regression analysis was performed to investigate the role of anemia and serum ferritin value for prediction of ICU and MV requirement. Results: Of patients, 46 (45.7%, 21 men) had anemia and 129 (68.2%, 88 men) had normal hemoglobin levels. The ICU requirement and MV rates were significantly higher in anemic group compared to non-anemic group (30.4% vs. 15.5%, respectively; p=0.028 and 23.9% vs. 10.9%, respectively; p=0.030). Median length of hospital and ICU stay was longer in patients with anemia (10.5 days vs. 8 days, respectively; p=0.047 and 0 days vs. 0 days, respectively; p=0.027). Anemia and ferritin were significant risk factors for ICU admission in univariate model and multivariate model [OR: 2.384 (95% CI: 1.084-5.246), p=0.031] vs. [OR: 2.738 (95% CI: 1.130-6.635), p=0.026] and [OR: 5.058 (95% CI: 1.968-12.998), p=0.001] vs. [OR: 4.218 (95% CI: 1.521-11.697), p=0.006]. Anemia was also a risk factor for MV [OR: 2.582 (95% CI: 1.075-6.197), p=0.034]. Conclusion: Requirement for therapy in ICU and MV were high among anemic COVID-19 patients. Anemia is also associated with prolonged length of stay in hospital and ICU.