An Overview to Cytokeratin Pattern of Cholesteatoma

dc.contributor.authorKoç, Ahmet
dc.contributor.authorEmre, Emrah
dc.date.accessioned2023-02-13T13:04:33Z
dc.date.available2023-02-13T13:04:33Z
dc.date.issued2015-04-01
dc.description.abstractABSTRACT Cholesteatoma is a destructive pathology characterized with progressive and chronic infiltration of keratinized squamous epithelium that can be seen the middle ear and mastoid regions of temporal bone. It has serious intra and extracranial complications which can be difficult to manage. Embryologic remnants of squamous epithelium, squamous metaplasia of middle ear epithelium, migration of epidermal cells from external ear canal and tympanic membrane and cell seeding because of middle ear surgery or trauma were all stated as causes of cholesteatoma. Cytokeratins are important markers of cell differentiation. The patterns of cytokeratin expression correlate well with the state of keratinocyte proliferation, migration and differentiation. These patterns are known to be affected during the formation of cholesteatoma. Increasing our knowledge about cytokeratin patterns may help us understand the unknown formation of cholesteatoma. In this review article, a literature survey was done about cytokeratin patterns of cholesteatoma.
dc.identifier.issn1309-470X
dc.identifier.issn1309-5994
dc.identifier.urihttps://hdl.handle.net/11443/422
dc.language.isoen
dc.publisherAcıbadem Mehmet Ali Aydınlar Üniversitesi
dc.titleAn Overview to Cytokeratin Pattern of Cholesteatoma
dc.typeArticle

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
An Overview to Cytokeratin Pattern of Cholesteatoma
Size:
86.22 KB
Format:
Adobe Portable Document Format

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed to upon submission
Description:

Collections