An Uncommon Cause of Hypernatremia in Very Low Birth Weight Premature Infants: Idiopathic Central Diabetes Insipidus

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dc.contributor.authorAktas, Selma
dc.contributor.authorKazanci, Ebru
dc.contributor.authorSemiz, Serap
dc.contributor.authorKorkmaz, Ayse
dc.date.accessioned2023-02-21T12:32:16Z
dc.date.available2023-02-21T12:32:16Z
dc.date.issued2021-01-01
dc.description.abstractCentral diabetes insipidus (CDI) is a water homeostasis disorder characterized by an inability to concentrate urine because of insufficient production of antidiuretic hormone. Dehydration with hypernatremia can occur during the neonatal period in preterm neonates in association with insensible water loss, high urine output, and reduced sodium excretion. A high index of suspicion is required to diagnose CDI in preterm neonates. We report two cases, who presented persistent hypernatremia with polyuria despite increased fluid supply and low sodium intake. CDI diagnosis was confirmed by the therapeutic test with oral vasopressin analog. Investigations were all normal
dc.description.abstractCDI was considered idiopathic. Persistent hypernatremia despite increased fluid intake with polyuria, hyposthenuria, low urine output, and high plasma osmolality is the key point for the diagnosis.
dc.description.issue2
dc.description.issueJUN
dc.description.pages177-179
dc.description.volume6
dc.identifier.doi10.5152/cjms.2021.3261
dc.identifier.urihttps://hdl.handle.net/11443/934
dc.identifier.urihttp://dx.doi.org/10.5152/cjms.2021.3261
dc.identifier.wosWOS:000672859300013
dc.publisherAVES
dc.relation.ispartofCYPRUS JOURNAL OF MEDICAL SCIENCES
dc.subjectCentral diabetes insipidus
dc.subjectpremature infants
dc.titleAn Uncommon Cause of Hypernatremia in Very Low Birth Weight Premature Infants: Idiopathic Central Diabetes Insipidus
dc.typeArticle
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