Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
Tarih
2015-01-01
Yazarlar
Basaran, Recep
Kaksi, Mustafa
Onoz, Mustafa
Balkuv, Ece
Sav, Aydin
Süreli Yayın başlığı
Süreli Yayın ISSN
Cilt Başlığı
Yayınevi
HINDAWI LTD
Dergi Adı
CASE REPORTS IN NEUROLOGICAL MEDICINE
Özet
Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenchyma, and spinal cord. Case. A 67-year-old male patient with progressive lower extremity weakness, urinary urgency, and sexual dysfunction has been admitted to our hospital. On his lumbar MRI, we detected an intradural lesion posterior to the L3 vertebral corpus. We resected the lesion by L3 total laminectomy. Immunohistological findings revealed strong and diffuse immunopositivity with vimentin, CD34, and bcl-2. Ki-67 proliferation index was 5-8\%. We did not detect any recurrence 12 months after his operation. Conclusion. SFT is mostly seen in young and middle-aged patients and should be considered among differential diagnosis in cases suffering from pain, hypoesthesia, and urinary dysfunction. Gross total resection should be primary treatment. Tumors that have high Ki-67 labeling should be followed up for potential recurrences.