Survival by self-destruction: A role for autophagy in the placenta?

dc.contributor.authorBildirici, I.
dc.contributor.authorLongtine, M. S.
dc.contributor.authorChen, B.
dc.contributor.authorNelson, D. M.
dc.date.accessioned2023-02-21T12:33:17Z
dc.date.available2023-02-21T12:33:17Z
dc.date.issued2012-01-01
dc.description.abstractAutophagy is a burgeoning area of research from yeast to humans. Although previously described as a death pathway, autophagy is now considered an important survival phenomenon in response to environmental stressors to which most organs are exposed. Despite an ever expanding literature in non-placental cells, studies of autophagy in the placenta are lagging. We review the regulation of autophagy, summarize available placental studies of autophagy, and highlight potential areas for future research. We believe that such studies will yield novel insights into how placentas protect the survival of the species by ``self-eating{''}. (C) 2012 Elsevier Ltd. All rights reserved.
dc.description.issue8
dc.description.issueAUG
dc.description.pages591-598
dc.description.volume33
dc.identifier.doi10.1016/j.placenta.2012.04.011
dc.identifier.urihttps://hdl.handle.net/11443/1445
dc.identifier.urihttp://dx.doi.org/10.1016/j.placenta.2012.04.011
dc.identifier.wosWOS:000306447500001
dc.publisherW B SAUNDERS CO LTD
dc.relation.ispartofPLACENTA
dc.subjectPlacenta
dc.subjectTrophoblast
dc.subjectAutophagy
dc.subjectApoptosis
dc.subjectmTOR
dc.subjectATG genes
dc.titleSurvival by self-destruction: A role for autophagy in the placenta?
dc.typeArticle

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