Holmium laser enucleation of the prostate: surgical, functional, and quality-of-life outcomes upon extended follow-up

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dc.contributor.authorAlkan, Ilter
dc.contributor.authorOzveri, Hakan
dc.contributor.authorAkin, Yigit
dc.contributor.authorIpekci, Tumay
dc.contributor.authorAlican, Yusuf
dc.date.accessioned2023-02-21T12:38:02Z
dc.date.available2023-02-21T12:38:02Z
dc.date.issued2016-01-01
dc.description.abstractObjectives: To evaluate the long-term surgical, functional, and quality-of-life (QoL) outcomes after Holmium laser enucleation of the prostate (HoLEP) in patients with symptomatic benign prostatic hyperplasia (BPH). Materials and Methods: We retrospectively reviewed recorded data on patients who underwent HoLEP between June 2002 and February 2005. Ninety-six patients were enrolled. Demographic, perioperative, and postoperative data were recorded. On follow-up, International Prostate Symptom Scores (IPSSs), prostate-specific antigen (PSA) levels, QoL scores, peak uroflowmetric data (Q(max) values), and post-voiding residual urine volumes (PVR volumes), were recorded. Complications were scored using the Clavien system. Statistical significance was set at p<0.05. Results: The mean follow-up time was 41.8 +/- 34.6 months and the mean patient age 73.2 +/- 8.7 years. The mean prostate volume was 74.6 +/- 34.3mL. Significant improvements in Q(max) values, QoL, and IPSSs and decreases in PSA levels and PVR volumes were noted during follow-up (all p values=0.001). The most common complication was a requirement for re-catheterisation because of urinary retention. Two patients had concomitant bladder tumours that did not invade the muscles. Eight patients (8.3\%) required re-operations
dc.description.abstractthree had residual adenoma, three urethral strictures, and two residual prostate tissue in the bladder. Stress incontinence occurred in one patient (1\%). All complications were of Clavien Grade 3a. We noted no Clavien 3b, 4, or 5 complications during follow-up. Conclusions: HoLEP improved IPSSs, Q(max) values, PVR volumes, and QoL and was associated with a low complication rate, during extended follow-up. Thus, HoLEP can be a viable option to transurethral resection of the prostate.
dc.description.issue2
dc.description.issueMAR-APR
dc.description.pages293-301
dc.description.volume42
dc.identifier.doi10.1590/S1677-5538.IBJU.2014.0561
dc.identifier.urihttps://hdl.handle.net/11443/2328
dc.identifier.urihttp://dx.doi.org/10.1590/S1677-5538.IBJU.2014.0561
dc.identifier.wosWOS:000375604900017
dc.publisherBRAZILIAN SOC UROL
dc.relation.ispartofINTERNATIONAL BRAZ J UROL
dc.subjectProstatic Hyperplasia
dc.subjectHolmium
dc.subjectLaser Therapy
dc.subjectProstate
dc.subjectQuality of Life
dc.titleHolmium laser enucleation of the prostate: surgical, functional, and quality-of-life outcomes upon extended follow-up
dc.typeArticle
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