Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

dc.contributor.authorKoc, Esin
dc.contributor.authorDemirel, Nihal
dc.contributor.authorBas, Ahmet Yagmur
dc.contributor.authorIsik, Dilek Ulubas
dc.contributor.authorHirfanoglu, Ibrahim Murat
dc.contributor.authorTunc, Turan
dc.contributor.authorSari, Fatma Nur
dc.contributor.authorKaratekin, Guner
dc.contributor.authorOzdemir, Ramazan
dc.contributor.authorAltunhan, Huseyin
dc.contributor.authorCetinkaya, Merih
dc.contributor.authorOzcan, Beyza
dc.contributor.authorOzkiraz, Servet
dc.contributor.authorCalkavur, Sebnem
dc.contributor.authorTekgunduz, Kadir Serafettin
dc.contributor.authorTastekin, Ayhan
dc.contributor.authorOzlu, Ferda
dc.contributor.authorOzyurt, Banu Mutlu
dc.contributor.authorOzdemir, Ahmet
dc.contributor.authorCetinkaya, Bilin
dc.contributor.authorDemirelli, Yasar
dc.contributor.authorKoklu, Esad
dc.contributor.authorCelik, Ulker
dc.contributor.authorTarakci, Nuriye
dc.contributor.authorArmangil, Didem
dc.contributor.authorOkulu, Emel
dc.contributor.authorNarter, Fatma
dc.contributor.authorMutlu, Birgul
dc.contributor.authorMert, Mustafa Kurthan
dc.contributor.authorBulbul, Ali
dc.contributor.authorAsker, Huseyin Selim
dc.contributor.authorUygur, Ozgun
dc.contributor.authorUslu, Ilker Sait
dc.contributor.authorErtugrul, Sabahattin
dc.contributor.authorAydemir, Cumhur
dc.contributor.authorCelik, Hasan Tolga
dc.contributor.authorKucuktasci, Kazim
dc.contributor.authorArslan, Selda
dc.contributor.authorErgin, Hacer
dc.contributor.authorZenciroglu, Aysegul
dc.contributor.authorYurttutan, Sadik
dc.contributor.authorOrman, Aysen
dc.contributor.authorTuncer, Oguz
dc.contributor.authorYasa, Beril
dc.contributor.authorAcunas, Betul
dc.contributor.authorTakci, Sahin
dc.contributor.authorGokmen, Zeynel
dc.contributor.authorOzkan, Hilal
dc.contributor.authorComert, Serdar
dc.contributor.authorUstun, Nuran
dc.contributor.authorMutlu, Mehmet
dc.contributor.authorBayraktar, Bilge Tanyeri
dc.contributor.authorBilgin, Leyla
dc.contributor.authorTuzun, Funda
dc.contributor.authorAydemir, Ozge
dc.contributor.authorGursoy, Tugba
dc.contributor.authorAkdag, Arzu
dc.contributor.authorMemisoglu, Asli
dc.contributor.authorCan, Emrah
dc.contributor.authorTerek, Demet
dc.contributor.authorBeken, Serdar
dc.contributor.authorTuran, Ozden
dc.contributor.authorGuzoglu, Nilufer
dc.contributor.authorOrs, Rahmi
dc.contributor.authorKale, Yusuf
dc.contributor.authorHekimoglu, Berna
dc.contributor.authorAylanc, Hakan
dc.contributor.authorEroglu, Funda
dc.contributor.authorSahin, Suzan
dc.contributor.authorKonak, Murat
dc.contributor.authorSarici, Dilek
dc.contributor.authorKilic, Ilknur
dc.contributor.authorHakan, Nilay
dc.date.accessioned2023-02-21T12:43:09Z
dc.date.available2023-02-21T12:43:09Z
dc.date.issued2019-01-01
dc.description.abstractObjective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of.1500 g were collected for infants who survived. Results Data from 69 NICUs were obtained. The mean birth weight and gestational age were 1137 +/- 245 g and 29 +/- 2.4 weeks, respectively. During the study period, 78\% of VLBW infants survived to discharge and 48\% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7\% of infants, necrotizing enterocolitis in 9.1\%, blood culture proven late-onset sepsis (LOS) in 21.1\%, blood culture negative LOS in 21.3\%, severe intraventricular hemorrhage in 5.4\% and severe retinopathy of prematurity in 11.1\%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8\% of infants. Antenatal steroids were administered to 42.9\% of mothers. Conclusion The present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs.
dc.description.issue12
dc.description.issueDEC 18
dc.description.volume14
dc.identifier.doi10.1371/journal.pone.0226679
dc.identifier.urihttps://hdl.handle.net/11443/2882
dc.identifier.urihttp://dx.doi.org/10.1371/journal.pone.0226679
dc.identifier.wosWOS:000534242500056
dc.publisherPUBLIC LIBRARY SCIENCE
dc.relation.ispartofPLOS ONE
dc.titleEarly neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society
dc.typeArticle

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