Ovarian reserve parameters and IVF outcomes in 510 women with poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP)
dc.contributor.author | Cakiroglu, Yigit | |
dc.contributor.author | Yuceturk, Aysen | |
dc.contributor.author | Karaosmanoglu, Ozge | |
dc.contributor.author | Kopuk, Sule Yildirim | |
dc.contributor.author | Korun, Zeynep Ece Utkan | |
dc.contributor.author | Herlihy, Nola | |
dc.contributor.author | Scott, Richard T. | |
dc.contributor.author | Tiras, Bulent | |
dc.contributor.author | Seli, Emre | |
dc.date.accessioned | 2023-02-21T12:37:40Z | |
dc.date.available | 2023-02-21T12:37:40Z | |
dc.date.issued | 2022-01-01 | |
dc.description.abstract | The aim of the current study was to characterize ovarian reserve parameters and IVF outcomes in women with a history of poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP). Reproductive age women (N=510 | |
dc.description.abstract | age range 30-45yo) diagnosed with POR based on Poseidon criteria were included in the study. PRP treatment resulted in higher AFC, higher serum AMH, lower serum FSH, and a higher number of mature oocytes and cleavage and blastocyst stage embryos. After PRP injection, 22 women (4.3\%) conceived spontaneously, 14 (2.7\%) were lost to follow up, and 474 (92.9\%) attempted IVF. Among women who attempted IVF, 312 (65.8\%) generated embryos and underwent embryo transfer, 83 (17.5\%) achieved a pregnancy, and 54 (11.4\%) achieved sustained implantation/live birth (SI/LB). In total, of the 510 women with POR and mean age of 40.3, PRP resulted in improvement of ovarian reserve parameters, a pregnancy rate of 20.5\% and SI/LB rate of 12.9\%. Our findings suggest that PRP treatment may be considered in women with POR. For wider clinical application, its clinical efficacy will need to be demonstrated in prospective randomized clinical trials. | |
dc.description.issue | 6 | |
dc.description.issue | MAR 31 | |
dc.description.pages | 2513-2523 | |
dc.description.volume | 14 | |
dc.identifier.uri | https://hdl.handle.net/11443/2277 | |
dc.identifier.wos | WOS:000782645200008 | |
dc.publisher | IMPACT JOURNALS LLC | |
dc.relation.ispartof | AGING-US | |
dc.subject | poor ovarian response | |
dc.subject | platelet rich plasma | |
dc.subject | in vitro fertilization | |
dc.title | Ovarian reserve parameters and IVF outcomes in 510 women with poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP) | |
dc.type | Article |
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