Relationships between Vitamin B12, Folate Levels and Clinical Features in Attention Deficit Hyperactivity Disorder and Attention Deficit Hyperactivity Disorder-Not Otherwise Specified

dc.contributor.authorOzturk, Yusuf
dc.contributor.authorTopal, Zehra
dc.contributor.authorDemir, Nuran
dc.contributor.authorTufan, Ali Evren
dc.date.accessioned2023-02-21T12:37:34Z
dc.date.available2023-02-21T12:37:34Z
dc.date.issued2020-01-01
dc.description.abstractAim: In this study, we aimed to compare the levels of vitamin 812 and folate in children with Attention Deficit and Hyperactivity Disorder (ADHD) and Attention Deficit and Hyperactivity Disorder-Not Otherwise Specified (ADHD-NOS). Materials and Methods: This study was planned as a cross-sectional, retrospective study. Patients were recruited between January 2012 and January 2013 and 205 case records were evaluated. The ADHD and ADHA-NOS groups were compared according to vitamin B12 and folate levels. Symptom severity was evaluated by the Turgay DSM-IV-Based Child and Adolescent Behavior Disorders Screening and Rating scale. Anxiety symptom severity was assessed by The Screen for Anxiety Related Emotional Disorders. Results: The average age of the children in the ADHD group was 10.88 +/- 3.02 (n=99) years, and the average age of the children in the ADHD-NOS group was 9.93 +/- 2.49 (n=106) years. There was no statistically significant difference between two groups in terms of Vitamin B12 level and folate level (p>0.05). A statistically significant negative correlation between the total number of diagnoses of a child and vitamin 812 levels was found. Folate levels correlated significantly with anxiety total scores generalized anxiety subscale. Conclusion: Vitamin B12 levels may be affected in children with impairing ADHD symptoms and increased comorbidities. The results of the study should be supported by future studies.
dc.description.issue3
dc.description.issueSEP
dc.description.pages257-263
dc.description.volume7
dc.identifier.doi10.4274/jpr.galenos.2019.45822
dc.identifier.urihttps://hdl.handle.net/11443/2263
dc.identifier.urihttp://dx.doi.org/10.4274/jpr.galenos.2019.45822
dc.identifier.wosWOS:000544838900013
dc.publisherGALENOS PUBL HOUSE
dc.relation.ispartofJOURNAL OF PEDIATRIC RESEARCH
dc.subjectADHD
dc.subjectvitamin B12
dc.subjectfolate
dc.titleRelationships between Vitamin B12, Folate Levels and Clinical Features in Attention Deficit Hyperactivity Disorder and Attention Deficit Hyperactivity Disorder-Not Otherwise Specified
dc.typeArticle

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