Sunlight may increase the FDG uptake value in primary tumors of patients with non-small cell lung cancer

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dc.contributor.authorMutlu, Hasan
dc.contributor.authorBuyukcelik, Abdullah
dc.contributor.authorKaya, Eser
dc.contributor.authorKibar, Mustafa
dc.contributor.authorSeyrek, Ertugrul
dc.contributor.authorYavuz, Sinan
dc.contributor.authorCalikusu, Zuleyha
dc.date.accessioned2023-02-21T12:36:02Z
dc.date.available2023-02-21T12:36:02Z
dc.date.issued2013-01-01
dc.description.abstractCurrently, positron emission tomography with computerized tomography (PET-CT) is the most sensitive technique for detecting extracranial metastases in non-small cell lung cancer (NSCLC). It has been reported that there is a correlation between the maximal standardized uptake value (SUVmax) of primary tumors and prognosis in patients with NSCLC. The effect of sunlight exposure on PET-CT SUVmax value is not known. Therefore, we aimed to evaluate the effect of sunlight exposure on PET-CT SUVmax a value in patients with NSCLC. A total of 290 patients with NSCLC from two different regions of Turkey (Kayseri, n=168 and Adana, n=122) that have different climate and sunlight exposure intensity, were included in the study. Age, gender, histology of cancer, cancer stage, smoking status, comorbidity and SUVmax of the primary tumor area at the time of staging were evaluated as prognostic factors. In the multivariate analysis, we detected that the region was the only independent factor affecting SUVmax (P=0.019). We identified that warmer climate and more sunlight exposure significantly increases the SUVmax value of the primary tumor area in patients with NSCLC. Further studies are warranted to clarify the issue.
dc.description.issue3
dc.description.issueMAR
dc.description.pages773-776
dc.description.volume5
dc.identifier.doi10.3892/ol.2013.1112
dc.identifier.urihttps://hdl.handle.net/11443/2037
dc.identifier.urihttp://dx.doi.org/10.3892/ol.2013.1112
dc.identifier.wosWOS:000315423900008
dc.publisherSPANDIDOS PUBL LTD
dc.relation.ispartofONCOLOGY LETTERS
dc.subjectlung cancer
dc.subjectmaximal standardized uptake value
dc.subjectseason
dc.subjectpositron emission tomography
dc.titleSunlight may increase the FDG uptake value in primary tumors of patients with non-small cell lung cancer
dc.typeArticle
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