Sunlight may increase the FDG uptake value in primary tumors of patients with non-small cell lung cancer
Sunlight may increase the FDG uptake value in primary tumors of patients with non-small cell lung cancer
Tarih
2013-01-01
Yazarlar
Mutlu, Hasan
Buyukcelik, Abdullah
Kaya, Eser
Kibar, Mustafa
Seyrek, Ertugrul
Yavuz, Sinan
Calikusu, Zuleyha
Süreli Yayın başlığı
Süreli Yayın ISSN
Cilt Başlığı
Yayınevi
SPANDIDOS PUBL LTD
Dergi Adı
ONCOLOGY LETTERS
Özet
Currently, positron emission tomography with computerized tomography (PET-CT) is the most sensitive technique for detecting extracranial metastases in non-small cell lung cancer (NSCLC). It has been reported that there is a correlation between the maximal standardized uptake value (SUVmax) of primary tumors and prognosis in patients with NSCLC. The effect of sunlight exposure on PET-CT SUVmax value is not known. Therefore, we aimed to evaluate the effect of sunlight exposure on PET-CT SUVmax a value in patients with NSCLC. A total of 290 patients with NSCLC from two different regions of Turkey (Kayseri, n=168 and Adana, n=122) that have different climate and sunlight exposure intensity, were included in the study. Age, gender, histology of cancer, cancer stage, smoking status, comorbidity and SUVmax of the primary tumor area at the time of staging were evaluated as prognostic factors. In the multivariate analysis, we detected that the region was the only independent factor affecting SUVmax (P=0.019). We identified that warmer climate and more sunlight exposure significantly increases the SUVmax value of the primary tumor area in patients with NSCLC. Further studies are warranted to clarify the issue.
Açıklama
Anahtar kelimeler
lung cancer, maximal standardized uptake value, season, positron emission tomography