Could the Long-Term Oncological Safety of Laparoscopic Surgery in Low-Risk Endometrial Cancer also Be Valid for the High-Intermediate- and High-Risk Patients? A Multi-Center Turkish Gynecologic Oncology Group Study Conducted with 2745 Endometrial Cancer Cases. (TRSGO-End-001)
dc.contributor.author | Vardar, Mehmet Ali | |
dc.contributor.author | Guzel, Ahmet Baris | |
dc.contributor.author | Taskin, Salih | |
dc.contributor.author | Gungor, Mete | |
dc.contributor.author | Ozgul, Nejat | |
dc.contributor.author | Salman, Coskun | |
dc.contributor.author | Kucukgoz-Gulec, Umran | |
dc.contributor.author | Khatib, Ghanim | |
dc.contributor.author | Taskiran, Cagatay | |
dc.contributor.author | Duender, Ilkkan | |
dc.contributor.author | Ortac, Firat | |
dc.contributor.author | Yuce, Kunter | |
dc.contributor.author | Terek, Cosan | |
dc.contributor.author | Simsek, Tayup | |
dc.contributor.author | Ozsaran, Aydin | |
dc.contributor.author | Onan, Anil | |
dc.contributor.author | Coban, Gonca | |
dc.contributor.author | Topuz, Samet | |
dc.contributor.author | Demirkiran, Fuat | |
dc.contributor.author | Takmaz, Ozguc | |
dc.contributor.author | Kose, M. Faruk | |
dc.contributor.author | Gocmen, Ahmet | |
dc.contributor.author | Seydaoglu, Gulsah | |
dc.contributor.author | Gumurdulu, Derya | |
dc.contributor.author | Ayhan, Ali | |
dc.date.accessioned | 2023-02-21T12:41:31Z | |
dc.date.available | 2023-02-21T12:41:31Z | |
dc.date.issued | 2021-01-01 | |
dc.description.abstract | This study was conducted to compare the long-term oncological outcomes of laparotomy and laparoscopic surgeries in endometrial cancer under the light of the 2016 ESMO-ESGO-ESTRO risk classification system, with particular focus on the high-intermediate- and high-risk categories. Using multicentric databases between January 2005 and January 2016, disease-free and overall survivals of 2745 endometrial cancer cases were compared according to the surgery route (laparotomy vs. laparoscopy). The high-intermediate- and high-risk patients were defined with respect to the 2016 ESMO-ESGO-ESTRO risk classification system, and they were analyzed with respect to differences in survival rates. Of the 2745 patients, 1743 (63.5\%) were operated by laparotomy, and the remaining were operated with laparoscopy. The total numbers of high-intermediate- and high-risk endometrial cancer cases were 734 (45\%) patients in the laparotomy group and 307 (30.7\%) patients in the laparoscopy group. Disease-free and overall survivals were not statistically different when compared between laparoscopy and laparotomy groups in terms of low-, intermediate-, high-intermediate- and high-risk endometrial cancer. In conclusion, regardless of the endometrial cancer risk category, long-term oncological outcomes of the laparoscopic approach were found to be comparable to those treated with laparotomy. Our results are encouraging to consider laparoscopic surgery for high-intermediate- and high-risk endometrial cancer cases. | |
dc.description.issue | 6 | |
dc.description.issue | DEC | |
dc.description.pages | 4328-4340 | |
dc.description.volume | 28 | |
dc.identifier.doi | 10.3390/curroncol28060368 | |
dc.identifier.uri | https://hdl.handle.net/11443/2727 | |
dc.identifier.uri | http://dx.doi.org/10.3390/curroncol28060368 | |
dc.identifier.wos | WOS:000747043700001 | |
dc.publisher | MDPI | |
dc.relation.ispartof | CURRENT ONCOLOGY | |
dc.subject | high-risk endometrial cancer | |
dc.subject | laparoscopic surgery | |
dc.subject | survival | |
dc.title | Could the Long-Term Oncological Safety of Laparoscopic Surgery in Low-Risk Endometrial Cancer also Be Valid for the High-Intermediate- and High-Risk Patients? A Multi-Center Turkish Gynecologic Oncology Group Study Conducted with 2745 Endometrial Cancer Cases. (TRSGO-End-001) | |
dc.type | Article |
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