Evaluation of serum 25-hidroxy vitamin D and zinc levels in asthmatic patients
Date
2018-01-01
Journal Title
Journal ISSN
Volume Title
Publisher
WALTER DE GRUYTER GMBH
Abstract
Introduction: We aimed to investigate the impact of serum zinc, and vitamin D levels on the development of asthma, and its clinical characteristics. Methods: In our cross-sectional study
50 patients who were diagnosed as atopic asthma and 70 healthy children consisted the control group. In both groups levels of vitamin D, and zinc were analyzed. Results: A statistically significant intergroup difference was not detected as for age, gender, body height (percentile), and weight (percentile) of the patients (p > 0.05). Mean vitamin D levels in the asthmatic patient, and control groups were 32.61 +/- 9.48 nmol/L, and 42.55 +/- 15.42 nmol/L, respectively. Between two groups a statistically significant difference was found (p = 0.001). Zinc levels were higher in the control group without any statistically significant difference between groups (p = 0.25). A statistically significant negative correlation (-0.635) was found between vitamin D levels, and severity of asthma in the patient group. As the level of vitamin D increased, a decrease in severity of asthma was seen (p = 0.04). Conclusion: Though larger series are needed to arrive at definitive conclusions, we think that vitamin D deficiency rather than zinc deficiency, might convey importance in the emergence, and exacerbation of asthma.
50 patients who were diagnosed as atopic asthma and 70 healthy children consisted the control group. In both groups levels of vitamin D, and zinc were analyzed. Results: A statistically significant intergroup difference was not detected as for age, gender, body height (percentile), and weight (percentile) of the patients (p > 0.05). Mean vitamin D levels in the asthmatic patient, and control groups were 32.61 +/- 9.48 nmol/L, and 42.55 +/- 15.42 nmol/L, respectively. Between two groups a statistically significant difference was found (p = 0.001). Zinc levels were higher in the control group without any statistically significant difference between groups (p = 0.25). A statistically significant negative correlation (-0.635) was found between vitamin D levels, and severity of asthma in the patient group. As the level of vitamin D increased, a decrease in severity of asthma was seen (p = 0.04). Conclusion: Though larger series are needed to arrive at definitive conclusions, we think that vitamin D deficiency rather than zinc deficiency, might convey importance in the emergence, and exacerbation of asthma.
Description
Keywords
Asthma, Child, Level, Vitamin D, Zinc