Browsing by Author "Alehan, Dursun"

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Clinical and electrophysiological evaluation of pediatric Wolff-Parkinson-White patients
(TURKISH SOC CARDIOLOGY, 2015-01-01) Yildirim, Isil; Ozer, Sema; Karagoz, Tevfik; Sahin, Murat; Ozkutlu, Suheyla; Alehan, Dursun; Celiker, Alpay
Objective: Wolff-Parkinson-White (WPW) syndrome presents with paroxysmal supraventricular tachycardia and is characterized by electro-cardiographic (ECG) findings of a short PR interval and a delta wave. The objective of this study was to evaluate the electrophysiological properties of children with WPW syndrome and to develop an algorithm for the management of these patients with limited access to electrophysiological study. Methods: A retrospective review of all pediatric patients who underwent electrophysiological evaluation for WPW syndrome was performed. Results: One hundred nine patients underwent electrophysiological evaluation at a single tertiary center between 1997 and 2011. The median age of the patients was 11 years (0.1-18). Of the 109 patients, 82 presented with tachycardia (median age 11 (0.1-18) years), and 14 presented with syncope (median age 12 (6-16) years)
Is transesophageal electrophysiologic study valuable in children with successful radiofrequency ablation of supraventricular tachycardia on follow-up for recurrence?
(TURKISH SOC CARDIOLOGY, 2016-01-01) Gulgun, Mustafa; Ozer, Sema; Karagoz, Tevfik; Akin, Alper; Aykan, Hayrettin Hakan; Ozkutlu, Suheyla; Alehan, Dursun; Celiker, Alpay
Objective: The aim of this study was to evaluate the efficacy of transesophageal electrophysiologic study (TEEPS) for the determination of supraventricular tachycardia (SVT) recurrences in symptomatic and asymptomatic children after successful radiofrequency ablation (RFA) for SVT. Methods: A total of 66 patients who underwent TEEPS after successful RFA were included. The demographic features, symptoms of the patients, and the characteristics of the recurrences induced by TEEPS were evaluated. The arrhythmia types induced during RFA were compared with those induced by TEEPS in terms of the compatibility of the diagnosis. Results: Forty-two (63.6\%) girls and 24 (36.4\%) boys with a mean age of 11.8 +/- 3.4 years were followed-up for 44.1 +/- 15.7 months. The average time between RFA and TEEPS was 5.2 +/- 5.9 months. The diagnoses during RFA were atrioventricular nodal reentrant tachycardia (AVNRT) in 47 of 66 patients, atrioventricular reentrant tachycardia (AVRT) in 18 of 66 patients, and ectopic atrial tachycardia in 1 of 66 patients. SVT was induced by TEEPS in 2 of 25 symptomatic and 5 of 41 asymptomatic patients. The SVT inducibility rate was 5.5\% (1/18) and 12.7\% (6/47) in patients with AVRT and AVNRT, respectively. In addition, 85.7\% (6/7) of all recurrences occurred within 3.5 months. The recurrences as AVNRT in 2 of 25 symptomatic patients occurred in the first month after RFA. AVNRT in 4 of 41 and AVRT in 1 of 41 asymptomatic patients were induced within 3.5 months and 15 months, respectively. Conclusion: TEEPS seems to be a valuable screening and diagnostic method for the determination of recurrence in symptomatic and asymptomatic children who underwent successful RFA.
Midterm experience with implantable cardioverter-defibrillators in children and young adults(dagger)
(OXFORD UNIV PRESS, 2010-01-01) Celiker, Alpay; Olgun, Hasim; Karagoz, Tevfik; Ozer, Sema; Ozkutlu, Suheyla; Alehan, Dursun
This single-centre study was undertaken to review our experience with implantable cardioverter-defibrillator (ICD) implantation in children with relatively different aetiologies. We retrospectively reviewed the records of the paediatric patients who underwent ICD implantation between October 2001 and December 2008. The data of these patients were collected by reviewing the patients' medical records and computerized departmental pacemaker databases. A total of 28 patients who underwent ICD implantation during this period were included in this study. The median age was 12 years and median weight was 32 kg. Most of the patients had ion-channel diseases (n = 13) or cardiomyopathy (n = 11). Devices were implanted for either secondary (n = 22) or primary (n = 6) prevention. The selected ICD generator type was single chamber in 22 patients, dual chamber in 5 patients, and biventricular in 1. Nineteen patients received 122 shocks. Fifteen of 22 patients (68.2\%) from the secondary prevention group and 2 of 6 patients (33.3\%) from the primary prevention group experienced at least one appropriate shock during a median period of 11.3 months (range: 4 days-6.5 years). Forty-two inappropriate shocks were delivered in seven (31.8\%) patients from the secondary prophylaxis group during a median period of 11.3 months. The most important reason for inappropriate shocks was T-wave oversensing. In six patients, lead-related acute or chronic complications occurred. The ICD was safe and effective in interrupting malignant arrhythmias in children and adolescents with a high risk of sudden cardiac death. However, the occurrence of lead complications is significant. The incidence of therapies delivered by the device, with appropriate and inappropriate shocks, was high and interfered with the quality of life. The most important reason for inappropriate shocks was T-wave oversensing. Careful programming is mandatory to reduce the inappropriate shocks.
Sağ Taraf Kardiyovasküler Yapılara Stent Uygulanması
(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2014-04-01) Şahin, Murat; Yıldırım, Işıl; Karagöz, Tevfik; Özkutlu, Süheyla; Özer, Sema; Alehan, Dursun; Çeliker, Alpay
ÖZET Amaç: Konjenital kalp hastalıklarında damar ve konduit darlıkları önemli bir sorundur. Merkezimizde sağ taraf kardiyovasküler yapılardaki darlıklara stent uygulanmış olan olguların klinik özellikleri ve sonuçları gözden geçirildi. Yöntemler: 1999-2010 yılları arasında merkezimizde sağ taraf kardiyovasküler yapılara 17 hastaya 18 stent implantasyonu yapıldı. Hastaların yaşı, geçirilmiş cerrahi öyküsü, darlık bölgesinin anatomisi, ölçülebilen hastalarda darlık distal ve proksimali arandaki basınç farkı belirlendi. Pulmoner arter dallarına, sağ ventrikül-pulmoner arter (RV-PA) arasına, Fontan konduitine ve sağ ventrikül çıkış yoluna balon ile genişletilebilir stent yerleştirilmiş olan hastalar çalışmaya dahil edildi. Klinik olarak siyanozu olmayan on üç hasta asiyanotik grup, siyanozu olan 4 hasta siyanotik grup olarak sınıflandırıldı. Bulgular: Olguların median yaşları 5 yıl (5 gün-17 yaş), vücut ağırlıkları 18 kg (3.2-65 kg) idi. Asiyanotik grupta stent implantasyonu öncesi ve sonrası median sistolik basınç farkı (mmHg) RV-PA arasında 103’den 73’e; Fontan dolaşımında ve pulmoner arter dallarında 8 mmHg’dan 1 mmHg’ya düştü. Asiyanotik grupta darlık çapında 2.4 kat artış, siyanotik grupta oksijen saturasyonun median %45’den %80’e yükseldiği gözlendi, klinik olarak hastaların siyanozunda belirgin düzelme gözlendi. İzlem sırasında altı hastada stentte daralma görüldü. Asiyanotik grupta bulunan hastalardan dördüne stent implantasyonu sonrası cerrahi girişim yapıldı. Cerrahi girişim nedeni bir hastada stentte kırılma iken diğer hastalarda restenozdu. Sonuç: Konjenital veya edinsel darlıkları olan ve balon anjiyoplastiye yanıt alınamayan çocuklarda stent implantasyonu cerrahi tedaviye alternatif etkili ve güvenli bir yöntemdir. Somatik büyüme, neointimal proliferasyon ya da rezidüel darlık nedeniyle redilatasyon veya cerrahi girişim gerekebileceği akılda tutulmalıdır. Konjenital kalp hastalıklarında ağır hipoksi varlığında ve/veya cerrahi şansının düşük olduğu durumlarda darlık bölgesine koroner stent uygulaması hayat kurtarıcı olabilir.