Browsing by Author "Seckin, Kerem Doga"

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Ovarian reserve assessment in crohn patients of reproductive age
(VIA MEDICA, 2021-01-01) Kadirogullari, Pinar; Bahat, Pinar Yalcin; Selcuki, Fitnat Topbas; Irak, Kader; Seckin, Kerem Doga
Objectives: Crohn's disease (CD) is a repeating bowel disease characterized by remission and exacerbation periods. The disease mostly affects adults of reproductive age. Women with desires to conceive are concerned about the effects of CD on their fertility. To demonstrate the relationship between ovarian reserve and CD anti-Mullerian hormone (AMH) levels, antral follicle count (AFC) and ovarian volume were evaluated. Material and methods: The prospective case-controlled study was conducted at a tertiary referral center in Istanbul between March-August 2019. Ovarian functions were evaluated in 50 patients with CD and in 95 healthy women. Serum gonadotropin and AMH levels were determined. AFCs and ovarian volumes were calculated for all subjects. Results: AMH levels were significantly lower in CD patients (2.1 +/- 0.8) compared to the control group (3.3 +/- 0.9) (P = 0.001). Serum AMH levels were significantly lower in patients with active CD (2.1 +/- 0.6) than the CD patients in remission (2.6 +/- 0.8) (p = 0.002). Ovarian volumes and AFC values were significantly lower in both ovaries in CD patients compared to the controls (p < 0.05). Conclusions: AMH levels, ovarian volume and AFC counts, and thus ovarian reserve was shown to be decreased in CD patients of reproductive age compared to healthy control subjects. Because possible effects of inflammatory damage may be seen in newly diagnosed female CD patients who desire to have a child, we believe that CD patients should be comprehensively assessed for ovarian reserve.
Sclerosing stromal tumor: a rare ovarian neoplasm
(GALENOS PUBL HOUSE, 2022-01-01) Kadirogullari, Pinar; Seckin, Kerem Doga
Sclerosing stromal tumor (SST) is an extremely rare and distinctive sex cord stromal tumor, which occurs predominantly in the second and third decades of life. SSTs make up 2-6\% of ovarian sex-cord stromal tumors. Due to the solid and distinct vascular structure of the tumor, it can be mistaken as a number of malignant ovarian tumors. As this specific neoplasm is very rare, it is not always possible to diagnose the tumor preoperatively with clinical and ultrasonographic findings. Furthermore, histopathological and immunohistochemical analysis does not always confirm the diagnosis. In this case report, clinical findings, histopathological features, and macroscopic appearance during laparoscopy of an SST are presented in a 20-year-old woman with pelvic pain. SST should be considered among the differential diagnosis of women with adnexal masses.
The Manchester procedure combined with laparoscopic sacrohysteropexy by retroperitoneal tunneling
(GALENOS PUBL HOUSE, 2022-01-01) Seckin, Kerem Doga; Kadirogullari, Pinar; Kiyak, Hueseyin; Dogan, Ali Riza; Tapisiz, Oemer Luetfi
This video will demonstrate a minimally invasive technique, in which the Manchester procedure was combined with laparoscopic sacrohysteropexy by retroperitoneal tunneling in patients with uterine prolapse and cervical elongation who wished to preserve the uterus. The principle steps and techniques to complete the operation are dictated in the video. The prolapse surgery was performed uneventfully, and the uterus was restored to its anatomical position. During the two years of follow-up, there were no complications from the prolapse or mesh-related events. No prolapse recurrence was observed. This technique facilitates uterine-sparing surgery, results in less bleeding and shorter operative time, and we believe that it may reduce the recurrence of prolapse due to the elongation of the cervix. (J Turk Ger Gynecol Assoc 2022