Browsing by Author "Tiras, Bulent"

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    Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency
    (IMPACT JOURNALS LLC, 2020-01-01) Cakiroglu, Yigit; Saltik, Ayse; Yuceturk, Aysen; Karaosmanoglu, Ozge; Kopuk, Sule Yildirim; Scott Jr., Richard T.; Tiras, Bulent; Seli, Emre
    We aimed to determine whether intraovarian injection of autologous platelet rich plasma (PRP) improves response to ovarian stimulation and in vitro fertilization (IVF) outcome in women with primary ovarian insufficiency (PO1). Women (N=311
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    Germline cells in ovarian surface epithelium of mammalians: a promising notion
    (BMC, 2012-01-01) Celik, Onder; Celik, Ebru; Turkcuoglu, Ilgin; Yilmaz, Ercan; Simsek, Yavuz; Tiras, Bulent
    It is a long held doctrine in reproductive biology that women are born with a finite number of oocytes and there is no oogenesis during the postnatal period. However, recent evidence challenges this by showing the presence of germ line stem cells in the human ovarian surface epithelium (OSE), which can serve as a source of germ cells, and differentiate into oocyte like structures. Postnatal renewal of oocytes may have enormous therapeutic potential especially in women facing the risk of premature ovarian failure idiopathically or iatrogenically after exposure to gonadotoxic chemotherapy and radiation for cancer therapy. This article reviews current knowledge on germ line stem cells in human OSE.
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    Ovarian reserve parameters and IVF outcomes in 510 women with poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP)
    (IMPACT JOURNALS LLC, 2022-01-01) Cakiroglu, Yigit; Yuceturk, Aysen; Karaosmanoglu, Ozge; Kopuk, Sule Yildirim; Korun, Zeynep Ece Utkan; Herlihy, Nola; Scott, Richard T.; Tiras, Bulent; Seli, Emre
    The aim of the current study was to characterize ovarian reserve parameters and IVF outcomes in women with a history of poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP). Reproductive age women (N=510