Browsing by Author "Tosuner, Zeynep"
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Item A Rare Confusing Nevus Variant: Meyerson Nevus(AVES, 2018-01-01) Yildiz, Pelin; Kucuk, Ozlem Su; Tosuner, Zeynep; Arici, Belfin Nur; Dizman, Didem; Deveci, Ugur; Demirkesen, CuyanMeyerson nevus is a rare benign entity described by Meyerson et al in 1971 as a melanocytic nevus surrounded by inflammatory, eczematous eruption that resolves spontaneously or by topical steriod therapy (fluticasone propionate, Abdi Ibrahim Ilac San. ve Tic. A.S., Istanbul), but the nevus persists. This entity is not well known and there is limited information in the literature. Since the lesion may develop suspicion for malignancy, it is important to keep this entity in mind. In this article we present three Meyerson nevi, two of which belong to one patient.Item Evaluation of Langerhans Cell Density in Oral Lichen Planus and Squamous Cell Carcinoma(DUZCE UNIV, 2020-01-01) Yildiz, Pelin; Sonmez, Fatma Cavide; Tosuner, Zeynep; Aytugar, EmreObjective: Oral mucosa exposed to many external factors. It has been suggested that oral pathologies may be related to cell-mediated immunity. Dendritic cells are antigen presenting cells that initiate adaptive cellular response. Langerhans cells(LCs), an important member of this group. Oral lichen planus(OLP) is a common chronic mucocutaneous inflammatory disease of unknown etiology. The most common malignancy in the oral cavity is oral squamous cell carcinoma(OSCC). In this study, we aimed to understand the role of LCs in OLP and OSCC which has an important role in mucosal defense. Methods: A total of 74 biopsies taken from Dentistry Department between 2013-2016 were included into the study. The 74 casesItem Kromoblastomikozis, Olgu Sunumu(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2017-04-01) Tosuner, Zeynep; Yıldız, Pelin; Dizman, Didem; Su, Özlem; Can, Füsun; Demirkesen, CüyanÖZET Kromoblastomikozis, Dematiaceae familyasından mantarların sebep olduğu, genellikle tropik bölgelerde görülen kronik bir mantar enfeksiyonudur. Yetmiş beş yaşında erkek hastanın ayak sırtında bir buçuk aydır olan, ağrısız nodülden alınan biyopsi, histolojik ve konvansiyonel histokimyasal inceleme sonucunda kromoblastomikozis olarak değerlendirilmiştir. Olgu, beklenenin aksine sessiz bir kliniğe sahip olması ve nadir görülmesi nedeniyle sunulmuştur.Item Skin Biopsy Results of Geriatric Patients Over a 5-year Period and the Frequency of Skin Diseases Before and After COVID-19 Pandemic(GALENOS PUBL HOUSE, 2022-01-01) Ozkaya, Dilek Biyik; Erfan, Gamze; Okuturlar, Yildiz; Tosuner, Zeynep; Demircioglu, Deniz; Timurkaynak, OzgurObjective: The number of older adults has increased throughout the world. Aging affects all the organs and creates psychological, physiologic and anatomic changes. One of the most important organs of the human body is the skin, which shows the effects of aging the most. This study aims to determine whether age, gender, and season of biopsy play a significant role in skin biopsy results. Additionally, the study investigates whether the frequency of skin diseases differs before and after the coronavirus disease-2019 (COVID-19) pandemic. Methods: We conducted a retrospective study on the histopathology results of patients over 65 years old between June 2016 and September 2021. The histopathology results were obtained from the Acibadem Pathology Department. Results: Of the 677 patients, 310 (45.8\%) were male and 367 (54.2\%) were female. The most common disease in all patients were benign cutaneous neoplasms (23\%), followed by eczematous disease (18.5\%) and epithelial cutaneous cancers (16.8\%). We divided the results into 12 groups: group 1: Urticaria, erythema and purpuras, group 2: Papulosquamous and eczematous diseases, group 3: Infectious diseases, group 4: Rheumatologic diseases and alopecia, group 5: Benign cutaneous neoplasms, group 6: Precancerous lesions, group 7: Basal cell carcinoma, squamous cell carcinoma, group 8: Cutaneous metastasis and other skin cancers, group 9: Pigmentation disorders, group 10: Pschycology related dermatological disorders, group 11: Granulomatous dermatitis, group 12: Bullous dermatitis. Before the COVID-19 pandemic, the most prevalent results were group 2 (21.3\%), followed by group 5 (20.4\%) and group 7 (16.7\%) whereas, after the COVID-19 pandemic, the most frequent results were group 5 (28.4\%) followed by group 7 (17.1\%), and group 6 (14.9\%). In terms of seasons, the most common diseases were group 5 (24.1\%) in winter, group 2 (21.6\%) in spring, group 5 (30.0\%) in summer, and group 2 (18.9\%) in autumn. Before the COVID-19 pandemic, the most common result was group 2 (21.3\%), followed by group 5 (20.4\%) and group 7 (16.7\%), and during the COVID-19 pandemic, the most common result was group 5 (28.4\%), followed by group 7 (17.1\%), group 6 (14.9\%). Conclusion: Many skin diseases affect the geriatric population. Geriatric patients face challenges such as multiple drug use, comorbidities, mobility problems and cognitive disorders. In our study, the most common diseases in all patients were benign cutaneous neoplasms (23\%), followed by eczematous diseases (18.5\%), and epithelial cutaneous cancers (16.8\%). Knowing about the frequency of skin diseases is critical for the early detection of precancerous and cancerous lesions.