Browsing by Author "Ulubil, Arif"

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    Post Endolaryngeal Laser Surgery Carbon Granuloma
    (GALENOS YAYINCILIK, 2017-01-01) Ertas, Burak; Emre, Ismet Emrah; Aksoy, Elif; Ulubil, Arif; Guven, Melih Guven; Tanyeri, Hasan; Unal, Omer Faruk
    Aim: This study was performed to highlight the phenomenon of carbon granulation formation after laser vocal cord surgery. Emphasis was put on the fact that these granulomas closely resemble tumor recurrence and due to the similarity of appearance, histological evaluation is necessary for diagnosis. Methods: This study included 35 male patients presenting to the Acibadem University Hospital with early-stage laryngeal cancer between 2009 and 2013. All patients underwent laser-assisted interventions on the vocal cords. Patient follow-up was continued for two years and granuloma formation or tumor recurrence was noted. Results: During the two-year follow-up period, a total of five patients presented with new vocal cord lesions. One of the cases was determined to be a tumor recurrence. The remaining four were carbon granulomas that regressed during the follow-up period. Conclusion: Although carbon granuloma formation is not very common, it is still frequent enough to be thoroughly discussed in the literature. With laser surgery for early-stage laryngeal cancer becoming more popular every day, the incidence of carbon granulomas is likely to increase. An algorithm for this type of lesion without putting patients' health at risk will be a valuable tool in the near future.
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    The Healing Effects of Autologous Mucosal Grafts in Experimentally Injured Rabbit Maxillary Sinuses
    (KOREAN SOC OTORHINOLARYNGOL, 2016-01-01) Topdag, Murat; Kara, Ahmet; Konuk, Esma; Demir, Necdet; Ozturk, Murat; Caliskan, Sebla; Topdag, Deniz Ozlem; Ulubil, Arif; Keskin, Ibrahim Gurkan; Iseri, Mete
    Objectives. Healing processes of the nose and paranasal sinuses are quite complex, and poorly understood. In this study, we aimed to compare the effect of mucosal autologous grafts on the degenerated rabbit maxillary sinus mucosa with spontaneous wound healing. It is hypothesized that mucosal grafts will enhance ciliogenesis and improve the morphology of regenerated cilia. Methods. Ten female New Zealand rabbits were included in the study. They underwent external maxillary sinus surgery through a transcutaneous approach. A total of 20 maxillary sinuses were randomly divided into 2 groups: `spontaneous healing group' and `autologous graft group.' The animals were sacrificed at the 14th day after the surgery. Scanning electron microscope (SEM), and light microscope were used for the evaluation. Results. Cellular composition of the graft group is better than the spontaneous healing group. The graft group had larger areas covered with ciliary epithelium than the spontaneous healing group, and the mean length of the cilias were also longer. Additionally, there were wider cilia with abnormal morphology areas in the spontaneous healing group. Conclusion. In our opinion, covering of the denuded areas with a graft improves re-epithelization, and may prevent the early complications after sinus surgeries.