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    HIF-1 alpha Levels in patients receiving chemoradiotherapy for locally advanced non-small cell lung carcinoma
    (ASSOC MEDICA BRASILEIRA, 2019-01-01) Afsar, Cigdem Usul; Uysal, Pelin
    AIM: To examine the relationship between treatment response and hypoxia-inducible factor-1 alpha (HIF-1 alpha) levels in patients with locally advanced non-small cell lung cancer (NSCLC) who received chemoradiotherapy (CRT). METHODS: Eighty patients with NSCLC were included in the study and treated at Acibadem Mehmet Ali Aydinlar University Medical Faculty. HIF-1 alpha levels were measured before and after CRT by the enzyme-linked immunosorbent assay (ELISA) method. RESULTS: Patients' stages were as follows