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    Utilization of biological variation data in the interpretation of laboratory test results - survey about clinicians' opinion and knowledge
    (CROATIAN SOC MEDICAL BIOCHEMISTRY \& LABORATORY MEDICINE, 2021-01-01) Emre, Humeyra Ozturk; Karpuzoglu, Fatma Hande; Coskun, Cihan; Sezer, Ebru Demirel; Ozturk, Ozlem Goruroglu; Ucar, Fatma; Cubukcu, Hikmet Can; Arslan, Fatma Demet; Deniz, Levent; Senes, Mehmet; Serteser, Mustafa; Yazici, Cevat; Yucel, Dogan; Coskun, Abdurrahman
    Introduction: To interpret test results correctly, understanding of the variations that affect test results is essential. The aim of this study is: 1) to evaluate the clinicians' knowledge and opinion concerning biological variation (BV), and 2) to investigate if clinicians use BV in the interpretation of test results. Materials and methods: This study uses a questionnaire comprising open-ended and close-ended questions. Questions were selected from the real-life numerical examples of interpretation of test results, the knowledge about main sources of variations in laboratories and the opinion of clinicians on BV. A total of 399 clinicians were interviewed, and the answers were evaluated using a scoring system ranked from A (clinician has the highest level of knowledge and the ability of using BV data) to D (clinician has no knowledge about variations in laboratory). The results were presented as number (N) and percentage (\%). Results: Altogether, 60.4\% of clinicians have knowledge of pre-analytical and analytical variations