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Permanent URI for this collectionhttps://hdl.handle.net/11443/932

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    The Effects of Adjuvant Chemoradiotherapy on Survival in Patients with Primary Laryngeal Cancer with Close Surgical Margins and Positive Surgical Margins
    (KARE PUBL, 2020-01-01) Inanc, Berrin; Inanc, Kubilay; Bilici, Suat; Cakir, Mustafa; Yigit, Ozgur
    OBJECTIVE The gold standard treatment for squamous cell carcinoma of the larynx is a resection of the primary tumour with negative surgical margins. In this study, we retrospectively investigated the effects of adjuvant concurrent chemoradiation on the survival rates of laryngeal cancer with close surgery margins and patients with positive surgery margin. METHODS A total of 40 patients treated with concurrent chemoradiation were included in this study. All of these patients had surgery for laryngeal cancer and had received 66 Gy (2Gy/fr) of radiotherapy and concurrent weekly cisplatin. Patients were stratified into two groups according to surgical margin status. Members of group 1 had a positive surgery margin
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    Relation between Histopathology of Head and Neck Cancers and FDG-PET/CT Parameters
    (KARE PUBL, 2021-01-01) Bilici, Suat; Gundogan, Cihan; Sunter, Ahmet Volkan; Misir, Esra; YigiT, Ozgur
    OBJECTIVE To analyse the relationship between histology of head and neck cancers and maximum standardized uptake value (SUVmax) and metabolic tumor volume (MTV). METHODS Positron-emission tomography (PET)/computed tomography (CT) examinations of patients with head and neck squamous cell carcinoma (SCC) and non-squamous cell carcinoma (non-SCC) tumors with 52 patients reviewed from 2007 to 2019 retrospectively. MTV and SUVmax values of primary tumor were measured in PET/CT and both groups were statistically compared. RESULTS The median SUVmax value was 17.88 (3-52) and MTV was 5.40 (0-329). No significant difference was established between the groups in terms of age, gender and MTV (p=0.948, p=0.166 and p=0.189) respectively. SUVmax value in SCC group was significantly higher (p=0.003) than the non-SCC group. CONCLUSION Head and neck squamous cell carcinomas (HNSCC) have higher SUVmax values than non SCC tumors. No significant difference was established between the groups in terms of MTV.