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Permanent URI for this collectionhttps://hdl.handle.net/11443/932

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Author: search.filters.author.Bulut, ErdoganSubject: search.filters.subject.microscopy

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    A New Hypothesis on the Frequency Discrimination of the Cochlea
    (AVES, 2017-01-01) Bulut, Erdogan; Uzun, Cem; Ozturk, Levent; Turan, Pinar; Kanter, Mehmet; Arbak, Serap
    OBJECTIVE: Medial olivocochlear efferent (MOCE) neurons innervate outer hair cells (OHCs) of the cochlea, which in turn leads to basilar membrane motion. We hypothesized that MOCE-induced alterations in basilar membrane motion, independent of traveling waves, is responsible for the cochlear frequency discrimination of sound. MATERIALS and METHODS: Eleven guinea pigs underwent bilateral otoscopic and audiologic evaluations under general anesthesia. The study comprised two parts. Part I (n=11) included spontaneous otoacoustic emission (SOAE) recordings with or without contralateral pure-tone acoustic stimuli (1 and 8 kHz) at 60 dB sound pressure level (SPL). Part II involved pure-tone (1 or 8 kHz) acoustic trauma in the right ears of two randomly selected subgroups (G1: 1 kHz