WOS
Permanent URI for this collectionhttps://hdl.handle.net/11443/932
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Item Tumor necrosis factor-alpha induced caspase-3 activation-related iNOS gene expression in ADP-activated platelets(TUBITAK SCIENTIFIC \& TECHNICAL RESEARCH COUNCIL TURKEY, 2017-01-01) Cevik, Ozge; Adiguzel, Zelal; Baykal, Ahmet Tarik; Sener, AzizePlatelets are sensitive cells and are easily activated by different stimulants in the circulation system. It is known that tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine and plays a role in inflammation. The role of TNF-a in the apoptotic process in blood platelets is unknown. In order to study the formation of apoptosis in platelets after incubation with TNF-alpha and/or ADP, several biomarkers were chosen: phosphatidylserine (PS) exposure and P-selectin binding