WOS

Permanent URI for this collectionhttps://hdl.handle.net/11443/932

Browse

Author: search.filters.author.Elpen, Pinar

Search Results

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    The effect of femoral nerve block on fracture healing via expressions of growth factors and beta-catenin
    (VIA MEDICA, 2016-01-01) Uslu, Serap; Irban, Arzu Gercek; Gereli, Arel; Aydinlar, Elif Ilgaz; Elpen, Pinar; Ince, Umit
    Introduction. Many patients of all ages are admitted to hospital due to bone fractures. The etiology of fracture has a very wide spectrum, ranging from motor accidents to pathological conditions such as tumors, osteoporosis, and others. Bone fracture healing is a well-programmed and well-organized process, but is also long and intractable. The outcome of this process is therefore affected by many factors, such as the patient's age, ethnicity, nutritional status, and extent of the fracture. At present, regional analgesic techniques are frequently applied in order to avoid the complications of systemic opioid administration, central block applications. Femoral block is one of the regional analgesic techniques frequently applied by anesthesiologists when the lower extremities are involved. In this study, we evaluated the effect of femoral nerve block on the healing of an experimental non-stabilized femur fracture via expression of TGF-beta, VEGF, and beta-catenin and bone histomorphometry in rats. Material and methods. In the control group, only the femoral fracture was performed and the bone was not fixated, similarly as in other groups. In the One-Day Block group, a one-time femoral nerve block was applied after the femoral fracture. In the Three-Day Block group, a daily femoral nerve block was performed for three days after the femoral fracture. On Days 4, 7, and 13, femurs were excised. The bone sections were stained with hematoxylin-eosin to evaluate bone tissue and Safranin O to assess callus tissue, cartilaginous tissue, and new bone areas. TGF-beta, VEGF, and beta-catenin were assessed by immunohistochemistry. Results. Histomorphometric analysis revealed that femoral block application had a positive impact on bone healing. TGF-beta expression in the One-Day and Three-Day Block Groups was significantly higher than in the control group at all times, as was also the case with VEGF expression. On day 13, beta-catenin expression was significantly higher in the Three-Day Block group than the others. Conclusions. The results of the study suggests that the applications of a femoral nerve block for perioperative analgesia, for either one day or three days, resulted in better and more rapid bone healing.
  • No Thumbnail Available
    Item
    ISA New Technical Mode in Mammography: Self-Compression Improves Satisfaction
    (AVES, 2019-01-01) Ulus, Sila; Kovan, Ozge; Arslan, Aydan; Elpen, Pinar; Aribal, Erkin
    Objective: We aimed to evaluate the mammography experience of patients using a manually controlled self-compression tool compared to their previous experience based on technician performed breast compression by a questionnaire survey study. Materials and Methods: The survey studies of 365 patients who underwent screening or diagnostic mammography between April 2017 and July 2017 at our center were reviewed retrospectively. Each patient had completed a 12-item questionnaire following mammography examinations. Women who never had a mammography before or who had a previous mammography examination more than 2 years ago or who did not want to use the self-compression device were excluded from the study. 106 women were included in the study. Results: Patient satisfaction was high. Regarding the comparison of the experience of the exam to previous ones, 70.8\% said it was a better experience. The examination was found comfortable by 85.4\% of the participants and 75.5\% found the examination more comfortable compared to previous ones. Only 11.3\% were anxious and 52.8\% declared they were less anxious compared to previous examinations. Regarding the attractiveness of the new design, 66.9\% declared they found the new design attractive, 39.7\% found it more attractive than previous examinations, and 27.3\% said the new design decreased anxiety. In the evaluation of impact of patient-assisted compression (PAC) on comfort, 80.2\% said that they found it more comfortable and 64.2\% said that PAC decreased anxiety. Furthermore, 72.6\% said the exam was shorter. Conclusion: Self-compression technique decreases pain and anxiety of women during mammography examinations and promises to enhance compliance of clients and patients with follow-up mammography recommendations.