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External Validation of the DynPG for Kidney Transplant Recipients
(LIPPINCOTT WILLIAMS \& WILKINS, 2021-01-01) Lenain, Remi; Dantan, Etienne; Giral, Magali; Foucher, Yohann; Asar, Ozgur; Naesens, Maarten; Hazzan, Marc; Fournier, Marie-Cecile
Background. In kidney transplantation, dynamic prediction of patient and kidney graft survival (DynPG) may help to promote therapeutic alliance by delivering personalized evidence-based information about long-term graft survival for kidney transplant recipients. The objective of the current study is to externally validate the DynPG. Methods. Based on 6 baseline variables, the DynPG can be updated with any new serum creatinine measure available during the follow-up. From an external validation sample of 1637 kidney recipients with a functioning graft at 1-year posttransplantation from 2 European transplantation centers, we assessed the prognostic performance of the DynPG. Results. As one can expect from an external validation sample, differences in several recipient, donor, and transplantation characteristics compared with the learning sample were observed. Patients were mainly transplanted from deceased donors (91.6\% versus 84.8\%