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Permanent URI for this collectionhttps://hdl.handle.net/11443/932

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Now showing 1 - 6 of 6
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    Study of epidemiological behaviour of malaria and its control in the Purulia district of West Bengal, India (2016-2020)
    (NATURE PORTFOLIO, 2022-01-01) Pradhan, Sayantan; Hore, Samrat; Maji, Suman Kumar; Manna, Simi; Maity, Abhijit; Kundu, Pratip Kumar; Maity, Krishna; Roy, Stabak; Mitra, Saptarshi; Dam, Paulami; Mondal, Rittick; Ghorai, Suvankar; Jawed, Junaid Jibran; Dutta, Subhadeep; Das, Sandip; Mandal, Sukhendu; Mandal, Sanjib; Kati, Ahmet; Sinha, Sangram; Maity, Amit Bikram; Dolai, Tuphan Kanti; Mandal, Amit Kumar; Ince, Ikbal Agah
    Purulia is a malaria-prone district in West Bengal, India, with approximately half of the blocks defined as malaria endemic. We analyzed the malaria case in each block of the Purulia district from January 1, 2016, to December 31, 2020. As per the API, 20 blocks of Purulia were assigned to four different categories (0-3) and mapped using ArcGIS software. An exponential decay model was fitted to forecast the trend of malaria cases for each block of Purulia (2021-2025). There was a sharp decrease in total malaria cases and API from 2016 to 2020 due to the mass distribution of LLINs. The majority of cases (72.63\%) were found in >= 15-year age group. Males were more prone to malaria (60.09\%). Malaria was highly prevalent among Scheduled Tribes (48.44\%). Six blocks were reported in Category 3 (high risk) and none in Category 0 (no risk) in 2016, while no blocks were determined to be in Category 3, and three blocks were in Category 0 in 2020. The exponential decay model prediction is oriented towards gaining malaria-free status in thirteen blocks of Purulia by 2025. This study will incite the government to uphold and strengthen the current efforts to meet the malaria elimination goals.
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    Comprehensive annotation of Glossina pallidipes salivary gland hypertrophy virus from Ethiopian tsetse flies: a proteogenomics approach
    (MICROBIOLOGY SOC, 2016-01-01) Abd-Alla, Adly M. M.; Kariithi, Henry M.; Cousserans, Franc Ois; Parker, Nicolas J.; Ince, Ikbal Agah; Scully, Erin D.; Boeren, Sjef; Geib, Scott M.; Mekonnen, Solomon; Vlak, Just M.; Parker, Andrew G.; Vreysen, Marc J. B.; Bergoin, Max
    Glossina pallidipes salivary gland hypertrophy virus (GpSGHV
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    Invertebrate Iridoviruses: A Glance over the Last Decade
    (MDPI, 2018-01-01) Ince, Ikbal Agah; Ozcan, Orhan; Ilter-Akulke, Ayca Zeynep; Scully, Erin D.; Ozgen, Arzu
    Members of the family Iridoviridae (iridovirids) are large dsDNA viruses that infect both invertebrate and vertebrate ectotherms and whose symptoms range in severity from minor reductions in host fitness to systemic disease and large-scale mortality. Several characteristics have been useful for classifying iridoviruses
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    Genomic Clues of a Multidrug-Resistant Bacterium from Cultured Domestic Silkworm (Bombyx mori L.)
    (AMER SOC MICROBIOLOGY, 2022-01-01) Mandal, Amit Kumar; Sarkar, Biraj; Mandal, Hrisikesh; Chakraborty, Arka Pratim; Das Mohapatra, Pradeep Kumar; Dam, Paulami; Mondal, Rittick; Some, Sudip; Sadat, Abdul; Ghati, Amit; Neog, Kartik; Mandal, Sukhendu; Ince, Ikbal Agah
    Enterobacter sp. strain ASE was isolated from the gut of an infected domestic silkworm (Bombyx mori L
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    Arthrobacter pityocampae sp nov., isolated from Thaumetopoea pityocampa (Lep., Thaumetopoeidae)
    (MICROBIOLOGY SOC, 2014-01-01) Ince, Ikbal Agah; Demirbag, Zihni; Kati, Hatice
    A bacterium (strain Tp2(T)) was isolated from a caterpillar of the pine processionary moth, Thaumetopoea pityocampa (Den. \& Schiff.) (Lepidoptera: Thaumetopoeidae), a destructive pine forest pest. The bacterium is a Gram-stain-positive, red-pigmented coccus, oxidase-negative, nitrate-reducing, non-motile and non-spore-forming. Strain Tp2(T) was subjected to a taxonomic study using polyphasic approach that included morphological and biochemical characterizations, 16S rRNA gene sequence analysis, DNA DNA hybridization, DNA G + C content analysis, comparative fatty acid profiles, and analyses of quinones and polar lipids. The 16S rRNA gene sequence of strain Tp2(T) revealed that Arthrobacter agilis DSM 20550(T) was the closest known strain (98\% 16S rRNA gene sequence similarity). DNA DNA hybridization of A. agilis DSM 20550(T) and strain Tp2(T) resulted in a DNA DNA relatedness value of 11.9\% (20.2\% reciprocal). The DNA base composition of strain Tp2(T) was 69.5 mol\%, which is consistent with the other recognized members of Actinobacteria that have a high G+C content in their genome. The polar lipid pattern of strain Tp2(T) consisted of diphosphatidylglycerol (major), phosphatidylglycerol and phosphatidylinositol and unknown glycolipids. The cellular fatty acids were anteiso C-15:0 and anteiso 0170 and the major menaquinone was MK-9(II-H-2). The peptidoglycan type was A3 alpha with an L-Lys L-Thr L-Ala(3) interpeptide bridge. The above-mentioned characterization qualifies strain Tp2(T) as genotypically and phenotypically distinct from closely related species of the genus Arthrobacter with validly published names. Strain Tp2(T) is therefore proposed to represent a novel species of the genus Arthrobacter, described as Arthrobacter pityocampae sp. nov. The type strain is Tp2(T) (=DSM 21719(T)=NCCB 100254(T)).
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    Temporal proteomic analysis and label-free quantification of viral proteins of an invertebrate iridovirus
    (MICROBIOLOGY SOC, 2015-01-01) Ince, Ikbal Agah; Boeren, Sjef; van Oers, Monique M.; Vlak, Just M.
    Invertebrate iridescent virus 6 (IIV-6) is a nucleocytoplasmic virus with a similar to 212 kb linear dsDNA genome that encodes 215 putative ORFs. The IIV-6 virion-associated proteins consist of at least 54 virally encoded proteins. One of our previous findings showed that most of these proteins are encoded by genes from the early transcriptional class. This indicated that these structural proteins may not only function in the formation of the virion, but also in the initial stage of viral infection. In the current study, we followed the protein expression profile of IIV-6 over time in Drosophila S2 cells by label-free quantification using a proteomic approach. A total of 95 virally encoded proteins were detected in infected cells, of which 37 were virion proteins. The expressed IIV-6 virion proteins could be categorized into three main clusters based on their expression profiles: proteins with stably low expression levels during infection, proteins with exponentially increasing expression levels during infection and proteins that were initially highly abundant, but showed slightly reduced levels after 48 h post-infection. We thus provided novel information on the kinetics of virion and infected cell-specific protein levels that assists in our understanding of gene regulation in this lesser-known DNA virus model.