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Permanent URI for this collectionhttps://hdl.handle.net/11443/932
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Item Clinical Significance of Serum NEDD9 Levels in Patients with Pancreatic Cancer(MDPI, 2018-01-01) Afsar, Cigdem Usul; Karabulut, Mehmet; Karabulut, Senem; Ozal, Safiye Tokgoz; Cikot, Murat; Serilmez, Murat; Tas, FarukIntroduction: Pancreatic cancer (PC) is a lethal malignancy. Various diagnostic, predictive, and prognostic biomarkers have been evaluated. This study was conducted to investigate the serum levels of neural precursor cell expressed developmentally downregulated protein 9 (NEDD9) in patients with PC and the relationship between tumor progression and known prognostic parameters. Materials and Methods: Serum samples were obtained on first admission before any treatment. Serum NEDD9 levels were determined using enzyme-linked immunosorbent assay (ELISA). Age- and sex-matched healthy controls were included in the analysis. Results: In a three year period, 32 patients with a pathologically-confirmed diagnosis of PC were enrolled in this study. The median age at diagnosis was 61 years, range 38 to 84 years