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Permanent URI for this collectionhttps://hdl.handle.net/11443/932

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Author: search.filters.author.Ozcan, Umit Aksoy

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    Solving the preoperative breast MRI conundrum: design and protocol of the MIPA study
    (SPRINGER, 2020-01-01) Sardanelli, Francesco; Trimboli, Rubina M.; Houssami, Nehmat; Gilbert, Fiona J.; Helbich, Thomas H.; Alvarez Benito, Marina; Balleyguier, Corinne; Bazzocchi, Massimo; Bult, Peter; Calabrese, Massimo; Camps Herrero, Julia; Cartia, Francesco; Cassano, Enrico; Clauser, Paola; de Andrade, Danubia A.; de Lima Docema, Marcos F.; Depretto, Catherine; Forrai, Gabor; Girometti, Rossano; Harms, Steven E.; Hilborne, Sarah; Ienzi, Raffaele; Lobbes, Marc B. I.; Losio, Claudio; Mann, Ritse M.; Montemezzi, Stefania; Obdeijn, Inge-Marie; Ozcan, Umit Aksoy; Pediconi, Federica; Preibsch, Heike; Raya-Povedano, Jose L.; Sacchetto, Daniela; Scaperrotta, Gianfranco P.; Schlooz, Margrethe; Szabo, Botond K.; Ulus, Ozden S.; Taylor, Donna B.; Van Goethem, Mireille; Veltman, Jeroen; Weigel, Stefanie; Wenkel, Evelyn; Zuiani, Chiara; Di Leo, Giovanni
    Despite its high diagnostic performance, the use of breast MRI in the preoperative setting is controversial. It has the potential for personalized surgical management in breast cancer patients, but two of three randomized controlled trials did not show results in favor of its introduction for assessing the disease extent before surgery. Meta-analyses showed a higher mastectomy rate in women undergoing preoperative MRI compared to those who do not. Nevertheless, preoperative breast MRI is increasingly used and a survey from the American Society of Breast Surgeons showed that 41\% of respondents ask for it in daily practice. In this context, a large-scale observational multicenter international prospective analysis (MIPA study) was proposed under the guidance of the European Network for the Assessment of Imaging in Medicine (EuroAIM). The aims were (1) to prospectively and systematically collect data on consecutive women with a newly diagnosed breast cancer, not candidates for neoadjuvant therapy, who are offered or not offered breast MRI before surgery according to local practice
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    Whole-Body MRI Screening in Asymptomatic Subjects
    (INT SCIENTIFIC INFORMATION INC, 2016-01-01) Ulus, Sila; Suleyman, Erdogan; Ozcan, Umit Aksoy; Karaarslan, Ercan
    Background: The aim of this study is to describe the technique and to evaluate the results of whole-body magnetic resonance imaging in an asymptomatic population. Material/Methods: Between March 2009 and December 2011, 118 consecutive subjects undergoing thorough medical check-up were prospectively included in the study. MRI was performed with a 205-cm moving table, parallel imaging and automatic image composing software. Results: In 83 subjects (70\%), 103 benign lesions were detected. Two malignant (adrenal and renal carcinoma) lesions and one precancerous (pancreatic mucinous carcinoma) lesion were detected. The most common lesions were renal cysts, liver hemangiomas, liver cysts, thyroid nodules, and uterine leiomyomas. Conclusions: WB-MRI is able to cover area from head to toes in one diagnostic work-up, and besides the anatomic regions evaluated by conventional radiological modalities, i.e. brain parenchyma, bones and extremities, can be evaluated in one examination.
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    The Great Mimicker: Zona Zoster at the Mastectomy Site Causing Contralateral Intramammary Lymph Node Enlargement
    (HINDAWI LTD, 2012-01-01) Ozcan, Umit Aksoy; Tezcanli, Evrim; Yildirim, Yesim; Garipagaoglu, Melahat
    Zona zoster is rarely observed in patients with malignancy
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    Space Occupying Lesions in the Fetal Chest Evaluated by MRI
    (KOWSAR PUBL, 2012-01-01) Ozcan, Umit Aksoy; Altun, Ersan; Abbasoglu, Latif
    Background: The most common space occupying lesions of the fetal thorax are congenital diaphragmatic hernia (CDH), congenital cystic adenomatoid malformation (CCAM), and bronchopulmonary sequestration (BPS). Although applications of prenatal MRI have been vastly improved in the recent years, its use in the assessment of space occupying lesions of the fetal chest differs among centers. Objectives: To evaluate MRI findings in the diagnosis and follow-up of space-occupying lesions in the fetal chest with the review of relevant literature. Patients and Methods: The fetuses with space-occupying lesions of the chest were retrieved from our 1.5T fetal MRI database of 347 patients. MRI features including the shape, signal characteristics, feeding artery, margin, mass effect, affected organ parts and anatomic location were reviewed. The results were correlated with the pathology results, follow-up and surgical findings. Results: Nineteen MR images of 17 fetuses (mean gestational age, 23.8 weeks) with space-occupying lesions (5 CCAMs including one involuted case), 2 BPSs, 2 hybrid lesions, 8 CDH) were evaluated. One case of CCAM completely involuted in utero, four newborns were operated, and the resulting 12 fetuses were terminated. The surgical and pathological findings were in accordance with MRI findings. Conclusion: MRI can reliably differentiate CDH from CCAM and BPS in utero. Follow-up is of utmost importance as lesions may involute or progress in utero. Prenatal MRI findings help postnatal decision-making, surgical planning and parental counseling. Copyright (C) 2012, Tehran University of Medical Sciences and Iranian Society of Radiology. Published by Kowsar Corp. All rights reserved.
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    Ultrasound-Guided Fine Needle Aspiration (USFNA) of Thyroid Nodules
    (KOWSAR PUBL, 2015-01-01) Ozcan, Umit Aksoy; Atahan, Safak
    Background: The goal of ultrasound guided fine-needle aspiration (USFNA) is to obtain most cellular specimen that represents the nodule. However, there is substantial variability in specimen cellularity depending on the obtaining techniques. While performing USFNA, it is not clear whether the needle tip should be placed at hypovascular or hypervascular site of the nodule to obtain more cells for cytological analysis. Objectives: The aim of the study was to assess whether USFNA of the hypovascular or hypervascular site of a thyroid nodule would reveal more cells for cytological analysis. Patients and Methods: Twenty-three consecutive patients with solid thyroid nodules larger than 2 cm were aspirated under color Doppler sonography guidance. First pass was from the hypovascular site and the second pass from the hypervascular site. The aspirates were scored from 1-3 by cytologist according to number of cell groups. Results: When only hypervascular site was used, adequate sampling was limited to 65\% of the cases. When both sites were evaluated together, overall adequate sampling was 91\%. Adding a sample from the hypervascular site to hypovascular aspirate increased the adequate sampling by 8\%. The highest pathological score was achieved when both hypo-and hypervascular site aspirates were evaluated together. Conclusions: The aspirates from the hypovascular and hypervascular sites of solid nodules are complementary and should be performed consecutively.