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Author: search.filters.author.Ozkan, Burak

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    The relation of anthropometric measurements and insulin resistance in patients with polycystic kidney disease
    (2016-01-01) Esen, Bennur; Gokmen, Emel Saglam; Kaya, Mahmut; Ozkan, Burak; Atay, Ahmet Engin
    Objective: To examine the frequency of insulin resistance (IR) and its relation with anthropometric measurements in patients with autosomal dominant polycystic kidney disease (ADPKD). Material and Methods: Nonobese 82 patients with ADPKD and 58 age matched healthy controls were enrolled into the study. None of participants were diabetic or receiving renal replacement therapies (RRT). IR was determined by homeostasis model assessment of insulin resistance (HOMA-IR) formula. Tanita body composition analyzer was used for anthropometric measurements. Creatinine clearance of participant were assessed by the modification of diet in renal diseases (MDRD). Results: Patients with ADPKD had significantly higher level of urea and creatinine, microalbuminuria, and lower level of MDRD. Body fat distribution and HOMA-IR in both the groups were similar. Systolic and diastolic blood pressure of patients were higher than those of controls. Conclusion: We failed to determine a higher frequency of IR among patients with ADPKD.
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    Robotic-assisted partial nephrectomy without using ureteral stent: a single center experience
    (AVES, 2016-01-01) Ozkan, Burak; Coskuner, Enis Rauf; Yalcin, Veli
    Objective: To share our results of robotic assisted partial nephrectomy (RAPN) we performed without using ureteral stent in a single center from Turkey. Material and methods: Medical records of consecutive 45 patients (34 men and 11 women) who underwent RAPN for kidney lesions between March 2011 and December 2014 were retrieved, and evaluated. All the procedures were performed by a transperitoneal approach without using ureteral stent prior to surgery. Renal artery clamping was used in all cases and intraoperative ultrasonography was used in 2 cases. Results: Patients undergoing RAPN had a mean tumor size of 4.42 cm (2-8) and a mean renal nephrometry score of 5.82 (4-11). The mean estimated blood loss was 250 mL (150-450 ml) and the mean operative time was 195 minutes (150-300). There was no statistical difference between the preoperative and postoperative serum creatinine levels at the first follow-up visit (0.9 vs. 0.95, p= 0.087). Surgical margin positivity was not detected in any patient, and the mean surgical margin distance was calculated as 0.4 mm (0.2-10). In only 1 patient disease recurrence was detected at the 21st month of the the follow-up period, and no distant metastases was reported in our patients at a mean follow-up of 10 months (3-36 mos). Our complication rate was 11.1\% and according to the Clavien system complications were as
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    Premature Ejaculation and Endocrine Disorders: A Literature Review
    (KOREAN SOC SEXUAL MEDICINE \& ANDROLOGY, 2022-01-01) Coskuner, Enis Rauf; Ozkan, Burak
    Premature ejaculation (PE) is the most common male sexual dysfunction, with 30\% of men experiencing PE worldwide. According to the generally accepted classification, there are two types of PE: lifetime PE and acquired PE. Various biological and psychological causes are known to be involved in the etiology of PE. However, due to the incomplete definition and etiopathogenesis of PE, there is no effective treatment. Although clinical and animal studies indicate that hormones play a role in controlling the ejaculation process, the precise endocrine mechanisms are unclear. In addition, little is known about the role of endocrine disorders in PE etiology. However, there is evidence that diabetes mellitus (DM), obesity, metabolic syndrome (MetS), thyroid gland disorders, pituitary gland disorders, and vitamin D deficiency affect the prevalence of PE. Moreover, it has been reported that the prevalence of PE decreases with treatment of these endocrine disorders. In this review, the relationship between PE and DM, MetS, obesity, vitamin D deficiency, and thyroid and pituitary gland disorders is summarized.
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    Does ureteral stenting matter for stone size? A retrospective analyses of 1361 extracorporeal shock wave lithotripsy patients
    (POLISH UROLOGICAL ASSOC, 2015-01-01) Ozkan, Burak; Dogan, Cagatay; Can, Gulce Ecem; Tansu, Nejat; Erozenci, Ahmet; Onal, Bulent
    Introduction The aim of our study was to determine the efficacy of ureteral stents for extracorporeal shock wave lithotripsy (SWL) treatment of pelvis renalis stones and to compare the results and complications in stented and non-stented patients. Material and methods Between 1995 and 2011, 1361 patients with pelvis renalis stones were treated with SWL. Patients were subdivided into three groups according to stone burden: <= 1 cm(2) (group 1
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    Spontaneous Retroperitoneal Hemorrhage Due to Chromophobic Type Renal Cell Carcinoma Requiring Emergency Action: Case Report
    (ORTADOGU AD PRES \& PUBL CO, 2012-01-01) Coskuner, Enis Rauf; Ozkan, Burak; Yalcin, Veli
    Spontaneous retroperitoneal hemorrhage is a quite rare disease. Appropriate treatment should be done after the cause of the disease had been detected. A complete clinical information and detailed radiologic examination are required for accurate diagnosis. In this study, a 76-year-old female patient who was evaluated in the emergency department of our hospital and found to have an abruptly developed retroperitoneal hemorrhage and hemorrhagic shock due to a big renal mass is presented. The patient required immediate radical nephrectomy. Pathological diagnosis was chromophobe type renal cell carcinoma with an invasion into the perinephric fat (pT3a). Subsequent staging after the operation failed to indicate any metastaic disease and there was no local or distant metastates in the first year follow-up.
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    Acute appendicitis coexisting with acute pyelonephritis causing diagnostic dilemma: a case report
    (SPRINGER, 2021-01-01) Ozkan, Burak; Ustun, Cemal; Coskuner, Enis Rauf
    Background Acute appendicitis and acute pyelonephritis are the most common diseases admitted to emergency departments. Both conditions have common symptoms such as flank pain, abdominal pain, and fever. Patients' history, physical examination, laboratory evaluation, and imaging methods are used to differentiate these two conditions. Diverticulitis, colitis, gynecological pathologies, and ureteral stones that mimic acute appendicitis should be kept in mind as differential diagnoses. Cases of pyelonephritis mimicking acute appendicitis have been reported in the literature, but there has not been a reported case in which acute appendicitis occurs during management of acute pyelonephritis. In this article, a case report which can cause such a diagnostic dilemma has been presented. Case presentation A 42-year-old female patient presented with clinical features suggestive of acute appendicitis that developed after a diagnosis of acute pyelonephritis. She underwent laparoscopic appendectomy on account of acute appendicitis during medical treatment for acute pyelonephritis. Physical examination showed only right costovertebral tenderness without any rebound tenderness at McBurney's point at the first admission, but during treatment rebound tenderness at McBurney's point was also detected. The Alvarado score of the patient was 5 at the first admission and 7 when acute appendicitis was diagnosed. The patient fully recovered and was discharged after both diseases were completely treated. Conclusions As seen in this case, it should be remembered that both diseases can be seen together which causes a diagnostic dilemma. If clinical or biochemical progression is detected in a patient under treatment, imaging methods should be repeated and additional ones with higher resolutions should be used.
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    The Role of Partial Nephrectomy without Arterial Embolization in Giant Renal Angiomyolipoma
    (HINDAWI LTD, 2012-01-01) Coskuner, Enis Rauf; Ozkan, Burak; Yalcin, Veli
    Angiomyolipoma is a benign neoplasm composed of varying admixtures of blood vessels, smooth muscle cells, and adipose tissue. Because of an increased risk of spontaneous haemorrhage, surgical approach is needed greater than 4-8 cm size. We here report our partial nephrectomy experience in the 24 cm size giant angiomyolipoma. 26-year-old woman referred to our clinic with a 24 cm size angiomyolipoma in her lower pole of right kidney. The inferior vena cava was deviated to the left by the mass. All the blood tests were normal and we offered her the choices of partial nephrectomy or nephrectomy. Right subcostal approach was used. The patient underwent resection of the mass with a safety region of 1 cm. Frozen section evaluation was consistent with angiomyolipoma and free for surgical margin. Warm ischemia time was 35min. and intraoperative bleeding volume was 200 cc. Postoperative 2nd day the drain was taken and hospital stay was 4 days. In literature we observed very rare angiomyolipoma cases with such a large dimension treated by partial nephrectomy without arterial embolization. If technically suitable partial nephrectomy is the main chioce in this kind of benign lesions in young patients.
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    Radical Prostatectomy in the Robotic Era. Comparison of Three Different Methods: Retropubic, Robotic and Perineal
    (2022-01-01) Ozkan, Burak; Coskuner, Enis Rauf
    Prostate cancer is the second most prevalent cancer among men and is the 6th cancer type leading to death. Starting with the use of PSA screening, there has been a steep increase in the number of cases diagnosed with and treated for localized prostate cancer. Radical prostatectomy use has increased following the increase in the number of cases and has become the golden standard for surgical procedures for their treatment. For over 50 years, while open retropubic and perineal methods have been used separately, advantages and disadvantages of each method have been expressed in official and unofficial grounds. The use of nerve-sparing radical prostatectomy that began particularly after the clearer definition of the neurovascular bundles and the anatomy of the prostate by Walsh and the improvements in continence and potency has proved open radical retropubic prostatectomy (RRP) more advantageous. The da Vinci Surgical System (Intuitive Surgical, Sunnyvale, CA, USA), developed to qualify disadvantages of laparoscopy in radical prostatectomy, came into use in 2000. With Abbou's identification of first robotic assisted radical prostatectomy (RARP), it finds increasing areas of application. Still there is need for further comparison of especially the three methods (RPP, RRP, and RARP) in prostate cancer treatment with more patients and longer follow-up periods. The objective of the first part of this paper is to provide a brief comparison of RRP and RARP results and in the second part we will discuss the perineal radical prostatectomy.