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Permanent URI for this collectionhttps://hdl.handle.net/11443/932

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Author: search.filters.author.Ugur, EsraHas files: No

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    Within- and between-subject biological variation data for serum zinc, copper and selenium obtained from 68 apparently healthy Turkish subjects
    (WALTER DE GRUYTER GMBH, 2022-01-01) Coskun, Abdurrahman; Carobene, Anna; Aarsand, Aasne K.; Aksungar, Fehime B.; Serteser, Mustafa; Sandberg, Sverre; Diaz-Garzon, Jorge; Fernandez-Calle, Pilar; Karpuzoglu, Fatma H.; Coskun, Cihan; Kizilkaya, Emine; Fidan, Damla; Jonker, Niels; Ugur, Esra; Unsal, Ibrahim; Chem, European Federation Clinical; Database, Task Grp Biol Variation
    Objectives Trace elements (TrEL) are nutritionally essential components in maintaining health and preventing diseases. There is a lack of reliable biological variation (BV) data for TrELs, required for the diagnosis and monitoring of TrEL disturbances. In this study, we aimed to provide updated within- and between-subject BV estimates for zinc (Zn), copper (Cu) and selenium (Se). Methods Weekly serum samples were drawn from 68 healthy subjects (36 females and 32 males) for 10 weeks and stored at -80 degrees C prior to analysis. Serum Zn, Cu and Se levels were measured using inductively-coupled plasma mass spectrometry (ICP-MS). Outlier and variance homogeneity analyses were performed followed by CV-ANOVA (Roraas method) to determine BV and analytical variation estimates with 95\% CI and the associated reference change values (RCV) for all subjects, males and females. Results Significant differences in mean concentrations between males and females were observed, with absolute and relative (\%) differences for Zn at 0.5 mu mol/L (3.5\%), Cu 2.0 mu mol/L (14.1\%) and Se 0.06 mu mol/L (6.0\%). The within-subject BV (CVI {[}95\% CI]) estimates were 8.8\% (8.2-9.3), 7.8\% (7.3-8.3) and 7.7\% (7.2-8.2) for Zn, Cu and Se, respectively. Within-subject biological variation (CVI) estimates derived for male and female subgroups were similar for all three TrELs. Marked individuality was observed for Cu and Se. Conclusions The data of this study provides updated BV estimates for serum Zn, Cu and Se derived from a stringent protocol and state of the art methodologies. Furthermore, Cu and Se display marked individuality, highlighting that population based reference limits should not be used in the monitoring of patients.
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    Relation Between The Trait Anger and Anger Expression Styles of The Nurses Working in Intensive Care and Palliative Care Units
    (ISTANBUL UNIV-CERRAHAPASA, 2017-01-01) Kocatepe, Vildan; Ugur, Esra; Karabacak, Ukke
    Aim: The study was conducted in order to determine the relation between the trait anger and anger expression styles and the care behaviour of the nurses working in intensive care and palliative care units. Method: 64 nurses working in 2nd and 3nd level intensive care and palliative care units of a research and training hospital was formed the sample of the definitive study. ``Trait Anger - Anger Expression Style Scales{''}, ``Caring Behaviors Inventory-24{''} and ``Personal Identification For{''} were used as data collection tools. The analysis of the data was made by using the SPSS 15.0 package software with number, percentage, average, standard deviation, correlation analyses, Kruskal Walli analyses, Mann Whitney U test, t test. Results: The nurses' continuous anger scores were found 20.32 +/- 4.98